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Clinical Isolates of Mycobacterium tuberculosis in Four European Hospitals are Uniformly Susceptible to Benzothiazinones 1-gen-2010 Pasca, MARIA ROSALIA; Degiacomi, Giulia; Ribeiro, Al; Zara, Francesca; De Mori, P; Heym, B; Mirrione, M; Brerra, Roberto; Pagani, Laura; Pucillo, L; Troupioti, P; Makarov, V; Cole, St; Riccardi, Giovanna
Decaprenylphosphoryl-beta-D-ribose 2’-epimerase from Mycobacterium tuberculosis is a magic drug target. 1-gen-2010 Buroni, Silvia; Manina, Giulia; Pasca, MARIA ROSALIA; DE JESUS LOPES RIBEIRO, ANA LUISA; Degiacomi, Giulia; DE ROSSI, Edda; Riccardi, Giovanna
Biological and structural characterization of theMycobacterium smegmatis nitroreductase NfnB, and its rolein benzothiazinone resistance 1-gen-2010 Manina, Giulia; Bellinzoni, M; Pasca, MARIA ROSALIA; Neres, J; Milano, Anna; DE JESUS LOPES RIBEIRO, Al; Buroni, Silvia; Škovierová, H; Dianišková, P; Mikušová, K; Marák, J; Makarov, V; Giganti, D; Haouz, A; Lucarelli, ANNA PAOLA; Degiacomi, Giulia; Piazza, Aurora; Chiarelli, Laurent; DE ROSSI, Edda; Salina, E; Cole, St; Alzari, Pm; Riccardi, Giovanna
Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis 1-gen-2011 De Jesus Lopes Ribeiro, Al; Degiacomi, Giulia; Ewann, F; Buroni, Silvia; Incandela, Ml; Chiarelli, Laurent; Mori, G; Kim, J; Contreras Dominguez, M; Park, Ys; Han, Sj; Brodin, P; Valentini, Giovanna; Rizzi, M; Riccardi, Giovanna; Pasca, MARIA ROSALIA
Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis. 1-gen-2012 Neres, J; Pojer, F; Molteni, Elisabetta; Chiarelli, Laurent; Dhar, N; Boy Röttger, S; Buroni, Silvia; Fullam, E; Degiacomi, Giulia; Lucarelli, Ap; Read, Rj; Zanoni, Giuseppe; Edmondson, De; DE ROSSI, Edda; Pasca, MARIA ROSALIA; Mckinney, Jd; Dyson, Pj; Riccardi, Giovanna; Mattevi, Andrea; Cole, St; Binda, Claudia
GarA is an essential regulator of metabolism in mycobacterium tuberculosis 1-gen-2013 Ventura, M.; Rieck, B.; Boldrin, F.; Degiacomi, G.; Bellinzoni, M.; Barilone, N.; Alzaidi, F.; Alzari, P. M.; Manganelli, R.; O'Hare, H. M.
The phosphatidyl-myo-inositol mannosyltransferase PimA is essential for Mycobacterium tuberculosis growth in vitro and in vivo 1-gen-2014 Boldrin, F.; Ventura, M.; Degiacomi, G.; Ravishankar, S.; Sala, C.; Svetlikova, Z.; Ambady, A.; Dhar, N.; Kordulakova, J.; Zhang, M.; Serafini, A.; Vishwas, V. G.; Kolly, G. S.; Kumar, N.; Palu`, G.; Guerin, M. E.; Mikusova, K.; Cole, K. M.; Manganelli, R.
Whole cell screen based identification of spiropiperidines with potent antitubercular properties 1-gen-2015 Tantry, S. J.; Degiacomi, G.; Sharma, S.; Jena, L. K.; Narayan, A.; Guptha, S.; Shanbhag, G.; Menasinakai, S.; Mallya, M.; Awasthy, D.; Balakrishnan, G.; Kaur, P.; Bhattacharjee, D.; Narayan, C.; Reddy, J.; Naveen Kumar, C. N.; Shandil, R.; Boldrin, F.; Ventura, M.; Manganelli, R.; Hartkoorn, R. C.; Cole, S. T.; Panda, M.; Markad, S. D.; Ramachandran, V.; Ghorpade, S. R.; Dinesh, N.
Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG. 1-gen-2015 Mori, Giorgia; Chiarelli, Laurent; Esposito, Marta; Makarov, V; Bellinzoni, M; Hartkoorn, Rc; Degiacomi, Giulia; Boldrin, F; Ekins, S; DE JESUS LOPES RIBEIRO, ANA LUISA; Marino, Lb; Centárová, I; Svetlíková, Z; Blaško, J; Kazakova, E; Lepioshkin, A; Barilone, N; Zanoni, Giuseppe; Porta, Alessio; Fondi, M; Fani, R; Baulard, Ar; Mikušová, K; Alzari, Pm; Manganelli, R; de Carvalho, Lp; Riccardi, Giovanna; Cole, St; Pasca, MARIA ROSALIA
Micrococcin P1 – A bactericidal thiopeptide active against Mycobacterium tuberculosis 1-gen-2016 Degiacomi, G.; Personne, Y.; Mondesert, G.; Ge, X.; Mandava, C. S.; Hartkoorn, R. C.; Boldrin, F.; Goel, P.; Peisker, K.; Benjak, A.; Barrio, M. B.; Ventura, M.; Brown, A. C.; Leblanc, V.; Bauer, A.; Sanyal, S.; Cole, S. T.; Lagrange, S.; Parish, T.; Manganelli, R.
The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis 1-gen-2017 Rosado, L. A.; Wahni, K.; Degiacomi, G.; Pedre, B.; Young, D.; De la Rubia, A. G.; Boldrin, F.; Martens, E.; Marcos-Pascual, L.; Sancho-Vaello, E.; Albesa-Jove, D.; Provvedi, R.; Martin, C.; Makarov, V.; Versees, W.; Verniest, G.; Guerin, M. E.; Mateos, L. M.; Manganelli, R.; Messens, J.
Essentiality of mmpL3 and impact of its silencing on Mycobacterium tuberculosis gene expression 1-gen-2017 Degiacomi, G.; Benjak, A.; Madacki, J.; Boldrin, F.; Provvedi, R.; Palu, G.; Kordulakova, J.; Cole, S. T.; Manganelli, R.
A phenotypic based target screening approach delivers new antitubercular CTP synthetase inhibitors 1-gen-2017 Esposito, Marta; Szadocka, Sára; Degiacomi, Giulia; Orena, BEATRICE SILVIA; Mori, Giorgia; Piano, Valentina; Boldrin, Francesca; Zemanova, Julia; Huszár, Stanislav; Barros, David; Ekins, Sean; Lelièvre, Joël; Manganelli, Riccardo; Mattevi, Andrea; Pasca, MARIA ROSALIA; Riccardi, Giovanna; Ballell, Lluis; Mikušová, Katarína; Chiarelli, Laurent
PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis 1-gen-2017 Rieck, B.; Degiacomi, G.; Zimmermann, M.; Cascioferro, A.; Boldrin, F.; Lazar-Adler, N. R.; Bottrill, A. R.; le Chevalier, F.; Frigui, W.; Bellinzoni, M.; Lisa, M. -N.; Alzari, P. M.; Nguyen, L.; Brosch, R.; Sauer, U.; Manganelli, R.; O'Hare, H. M.
Promoter mutagenesis for fine-tuning expression of essential genes in Mycobacterium tuberculosis 1-gen-2018 Boldrin, F.; Degiacomi, G.; Serafini, A.; Kolly, G. S.; Ventura, M.; Sala, C.; Provvedi, R.; Palu, G.; Cole, S. T.; Manganelli, R.
A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK 1-gen-2018 Chiarelli, L; Mori, G; Orena, Bs; Esposito, M; Lane, T; de Lopes Jesus Ribeiro, Al; Degiacomi, G; Zemanova, J; Szadocka, S; Huszar, S; Palcekova, Z; Manfredi, M; Gosetti, F; Lelievre, J; Ballell, L; Kazakova, E; Makarov, V; Marengo, E; Mikusova, K; Cole, St; Riccardi, G; Ekins, S; Pasca, Mr
Mycobacterium abscessus, an Emerging and Worrisome Pathogen among Cystic Fibrosis Patients. 1-gen-2019 Degiacomi, G; Sammartino, Jc; Chiarelli, Lr; Riabova, O; Makarov, V; Pasca, Mr.
Promiscuous Targets for Antitubercular Drug Discovery: The Paradigm of DprE1 and MmpL3 1-gen-2020 Degiacomi, Giulia; Belardinelli, Juan Manuel; Pasca, Maria Rosalia; De Rossi, Edda; Riccardi, Giovanna; Chiarelli, Laurent R
New insights into the mechanism of action of the thienopyrimidine antitubercular prodrug TP053 1-gen-2020 Chiarelli, Lr; Salina, Eg; Mori, G; Azhikina, T; Riabova, O; Lepioshkin, A; Grigorov, A; Forbak, M; Madacki, J; Orena, Bs; Manfredi, M; Gosetti, F; Buzzi, A; Degiacomi, G; Sammartino, Jc; Marengo, E; Korduláková, J; Riccardi, G; Mikušová, K; Makarov, V; Pasca, Mr.
First triclosan-based macrocyclic inhibitors of InhA enzyme 1-gen-2020 Rodriguez, F; Saffon, N; Sammartino, Jc; Degiacomi, G; Pasca, Mr; Lherbet, C.
Mostrati risultati da 1 a 20 di 41
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