Sfoglia per Autore
DprE1, a new taxonomic marker in mycobacteria.
2013-01-01 Incandela, Ml; Perrin, E; Fondi, M; de Jesus Lopes Ribeiro, Al; Mori, Giorgia; Moiana, A; Gramegna, M; Fani, R; Riccardi, Giovanna; Pasca, MARIA ROSALIA
Synthesis of 3-heteryl substituted pyrrolidine-2,5-diones via catalytic Michael reaction and evaluation of their inhibitory activity against InhA and Mycobacterium tuberculosis
2014-01-01 Matviiuk, T; Mori, Giorgia; Lherbet, C; Rodriguez, F; Pasca, MARIA ROSALIA; Gorichko, M; Guidetti, B; Voitenko, Z; Baltas, M.
Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis.
2014-01-01 Albesa Jove, D; Chiarelli, Laurent; Makarov, V; Pasca, MARIA ROSALIA; Urresti, S; Mori, Giorgia; Salina, E; Vocat, A; Comino, N; Mohorko, E; Ryabova, S; Pfeiffer, B; Lopes Ribeiro, Al; Rodrigo Unzueta, A; Tersa, M; Zanoni, Giuseppe; Buroni, Silvia; Altmann, Kh; Hartkoorn, Rc; Glockshuber, R; Cole, St; Riccardi, Giovanna; Guerin, M. E.
Pyridine-3,4-dicarboximide as starting material for the total synthesis of the natural product eupolauramine and its isomer iso-eupolauramine endowed with anti-tubercular activities
2015-01-01 Perdigao, G; Deraeve, C; Mori, Giorgia; Pasca, MARIA ROSALIA; Pratviel, G; Bernardes Genisson, V.
2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1.
2015-01-01 Neres, J; Hartkoorn, Rc; Chiarelli, Laurent; Gadupudi, R; Pasca, MARIA ROSALIA; Mori, Giorgia; Venturelli, A; Savina, S; Makarov, V; Kolly, Gs; Molteni, E; Binda, Claudia; Dhar, N; Ferrari, S; Brodin, P; Delorme, V; Landry, V; de Jesus Lopes Ribeiro, Al; Farina, D; Saxena, P; Pojer, F; Carta, A; Luciani, R; Porta, Alessio; Zanoni, G; DE ROSSI, Edda; Costi, Mp; Riccardi, Giovanna; Cole, S. T.
Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG.
2015-01-01 Mori, Giorgia; Chiarelli, Laurent; Esposito, Marta; Makarov, V; Bellinzoni, M; Hartkoorn, Rc; Degiacomi, Giulia; Boldrin, F; Ekins, S; DE JESUS LOPES RIBEIRO, ANA LUISA; Marino, Lb; Centárová, I; Svetlíková, Z; Blaško, J; Kazakova, E; Lepioshkin, A; Barilone, N; Zanoni, Giuseppe; Porta, Alessio; Fondi, M; Fani, R; Baulard, Ar; Mikušová, K; Alzari, Pm; Manganelli, R; de Carvalho, Lp; Riccardi, Giovanna; Cole, St; Pasca, MARIA ROSALIA
Design, synthesis and evaluation of new GEQ derivatives as inhibitors of InhA enzyme and Mycobacterium tuberculosis growth.
2015-01-01 Chollet, A; Mori, Giorgia; Menendez, C; Rodriguez, F; Fabing, I; Pasca, MARIA ROSALIA; Madacki, J; Korduláková, J; Constant, P; Quémard, A; Bernardes Génisson, V; Lherbet, C; Baltas, M.
Pyrrolidinone and pyrrolidine derivatives: Evaluation as inhibitors of InhA and Mycobacterium tuberculosis.
2016-01-01 Matviiuk, T; Madacki, J; Mori, Giorgia; Orena, BEATRICE SILVIA; Menendez, C; Kysil, A; André Barrès, C; Rodriguez, F; Korduláková, J; Mallet Ladeira, S; Voitenko, Z; Pasca, MARIA ROSALIA; Lherbet, C; Baltas, M.
Evaluation of the inhibitory activity of (aza)isoindolinone-type compounds: Towards in vitro InhA action, Mycobacterium tuberculosis growth and mycolic acid biosynthesis.
2016-01-01 Chollet, A; Stigliani, Jl; Pasca, MARIA ROSALIA; Mori, Giorgia; Lherbet, C; Constant, P; Quémard, A; Bernadou, J; Pratviel, G; Bernardes Génisson, V.
Design, Syntheses, and Anti-TB Activity of 1,3-Benzothiazinone Azide and Click Chemistry Products Inspired by BTZ043
2016-01-01 Tiwari, R.; Miller, P. A.; Chiarelli, Laurent; Mori, Giorgia; Šarkan, M.; Centárová, I.; Cho, S.; Mikušová, K.; Franzblau, S. G.; Oliver, A. G.; Miller, M. J.
Triazolophthalazines: Easily Accessible Compounds with Potent Antitubercular Activity.
2016-01-01 Veau, D; Krykun, S; Mori, Giorgia; Orena, BEATRICE SILVIA; Pasca, MARIA ROSALIA; Frongia, C; Lobjois, V; Chassaing, S; Lherbet, C; Baltas, M.
New and old hot drug targets in tuberculosis
2016-01-01 Chiarelli, Laurent; Mori, Giorgia; Esposito, Marta; Orena, BEATRICE SILVIA; Pasca, MARIA ROSALIA
New prodrugs against tuberculosis
2017-01-01 Mori, Giorgia; Chiarelli, Laurent; Riccardi, Giovanna; Pasca, MARIA ROSALIA
A phenotypic based target screening approach delivers new antitubercular CTP synthetase inhibitors
2017-01-01 Esposito, Marta; Szadocka, Sára; Degiacomi, Giulia; Orena, BEATRICE SILVIA; Mori, Giorgia; Piano, Valentina; Boldrin, Francesca; Zemanova, Julia; Huszár, Stanislav; Barros, David; Ekins, Sean; Lelièvre, Joël; Manganelli, Riccardo; Mattevi, Andrea; Pasca, MARIA ROSALIA; Riccardi, Giovanna; Ballell, Lluis; Mikušová, Katarína; Chiarelli, Laurent
Mechanochemical Synthesis and Biological Evaluation of Novel Isoniazid Derivatives with Potent Antitubercular Activity.
2017-01-01 Oliveira, Pfm; Guidetti, B; Chamayou, A; André Barrès, C; Madacki, J; Korduláková, J; Mori, Giorgia; Orena, BEATRICE SILVIA; Chiarelli, Laurent; Pasca, MARIA ROSALIA; Lherbet, C; Carayon, C; Massou, S; Baron, M; Baltas, M.
Discovery and development of novel salicylate synthase (MbtI) furanic inhibitors as antitubercular agents
2018-01-01 Chiarelli, Laurent R; Mori, Matteo; Barlocco, Daniela; Beretta, Giangiacomo; Gelain, Arianna; Pini, Elena; Porcino, Marianna; Mori, Giorgia; Stelitano, Giovanni; Costantino, Luca; Lapillo, Margherita; Bonanni, Davide; Poli, Giulio; Tuccinardi, Tiziano; Villa, Stefania; Meneghetti, Fiorella
The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase
2018-01-01 Mori, G; Orena, Bs; Franch, C; Mitchenall, La; Godbole, Aa; Rodrigues, L; Aguilar-Pérez, C; Zemanová, J; Huszár, S; Forbak, M; Lane, Tr; Sabbah, M; Deboosere, N; Frita, R; Vandeputte, A; Hoffmann, E; Russo, R; Connell, N; Veilleux, C; Kumar, R; Kumar, P; Freundlich, Js; Brodin, P; Aínsa, Ja; Nagaraja, V; Maxwell, A; Mikušová, K; Pasca, Mr; Ekins, S.
A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK
2018-01-01 Chiarelli, L; Mori, G; Orena, Bs; Esposito, M; Lane, T; de Lopes Jesus Ribeiro, Al; Degiacomi, G; Zemanova, J; Szadocka, S; Huszar, S; Palcekova, Z; Manfredi, M; Gosetti, F; Lelievre, J; Ballell, L; Kazakova, E; Makarov, V; Marengo, E; Mikusova, K; Cole, St; Riccardi, G; Ekins, S; Pasca, Mr
Shifts of Faecal Microbiota During Sporadic Colorectal Carcinogenesis
2018-01-01 Mori, G; Rampelli, S; Orena, Bs; Rengucci, C; De Maio, G; Barbieri, G; Passardi, A; Casadei Gardini, A; Frassineti, Gl; Gaiarsa, S; Albertini, Am; Ranzani, Gn; Calistri, D; Pasca, Mr
Gut Microbiota Analysis in Postoperative Lynch Syndrome Patients
2019-01-01 Mori, G; Orena, Bs; Cultrera, I; Barbieri, G; Albertini, Am; Ranzani, Gn; Carnevali, I; Tibiletti, Mg; Pasca, Mr
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| DprE1, a new taxonomic marker in mycobacteria. | 1-gen-2013 | Incandela, Ml; Perrin, E; Fondi, M; de Jesus Lopes Ribeiro, Al; Mori, Giorgia; Moiana, A; Gramegna, M; Fani, R; Riccardi, Giovanna; Pasca, MARIA ROSALIA | |
| Synthesis of 3-heteryl substituted pyrrolidine-2,5-diones via catalytic Michael reaction and evaluation of their inhibitory activity against InhA and Mycobacterium tuberculosis | 1-gen-2014 | Matviiuk, T; Mori, Giorgia; Lherbet, C; Rodriguez, F; Pasca, MARIA ROSALIA; Gorichko, M; Guidetti, B; Voitenko, Z; Baltas, M. | |
| Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis. | 1-gen-2014 | Albesa Jove, D; Chiarelli, Laurent; Makarov, V; Pasca, MARIA ROSALIA; Urresti, S; Mori, Giorgia; Salina, E; Vocat, A; Comino, N; Mohorko, E; Ryabova, S; Pfeiffer, B; Lopes Ribeiro, Al; Rodrigo Unzueta, A; Tersa, M; Zanoni, Giuseppe; Buroni, Silvia; Altmann, Kh; Hartkoorn, Rc; Glockshuber, R; Cole, St; Riccardi, Giovanna; Guerin, M. E. | |
| Pyridine-3,4-dicarboximide as starting material for the total synthesis of the natural product eupolauramine and its isomer iso-eupolauramine endowed with anti-tubercular activities | 1-gen-2015 | Perdigao, G; Deraeve, C; Mori, Giorgia; Pasca, MARIA ROSALIA; Pratviel, G; Bernardes Genisson, V. | |
| 2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1. | 1-gen-2015 | Neres, J; Hartkoorn, Rc; Chiarelli, Laurent; Gadupudi, R; Pasca, MARIA ROSALIA; Mori, Giorgia; Venturelli, A; Savina, S; Makarov, V; Kolly, Gs; Molteni, E; Binda, Claudia; Dhar, N; Ferrari, S; Brodin, P; Delorme, V; Landry, V; de Jesus Lopes Ribeiro, Al; Farina, D; Saxena, P; Pojer, F; Carta, A; Luciani, R; Porta, Alessio; Zanoni, G; DE ROSSI, Edda; Costi, Mp; Riccardi, Giovanna; Cole, S. T. | |
| Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG. | 1-gen-2015 | Mori, Giorgia; Chiarelli, Laurent; Esposito, Marta; Makarov, V; Bellinzoni, M; Hartkoorn, Rc; Degiacomi, Giulia; Boldrin, F; Ekins, S; DE JESUS LOPES RIBEIRO, ANA LUISA; Marino, Lb; Centárová, I; Svetlíková, Z; Blaško, J; Kazakova, E; Lepioshkin, A; Barilone, N; Zanoni, Giuseppe; Porta, Alessio; Fondi, M; Fani, R; Baulard, Ar; Mikušová, K; Alzari, Pm; Manganelli, R; de Carvalho, Lp; Riccardi, Giovanna; Cole, St; Pasca, MARIA ROSALIA | |
| Design, synthesis and evaluation of new GEQ derivatives as inhibitors of InhA enzyme and Mycobacterium tuberculosis growth. | 1-gen-2015 | Chollet, A; Mori, Giorgia; Menendez, C; Rodriguez, F; Fabing, I; Pasca, MARIA ROSALIA; Madacki, J; Korduláková, J; Constant, P; Quémard, A; Bernardes Génisson, V; Lherbet, C; Baltas, M. | |
| Pyrrolidinone and pyrrolidine derivatives: Evaluation as inhibitors of InhA and Mycobacterium tuberculosis. | 1-gen-2016 | Matviiuk, T; Madacki, J; Mori, Giorgia; Orena, BEATRICE SILVIA; Menendez, C; Kysil, A; André Barrès, C; Rodriguez, F; Korduláková, J; Mallet Ladeira, S; Voitenko, Z; Pasca, MARIA ROSALIA; Lherbet, C; Baltas, M. | |
| Evaluation of the inhibitory activity of (aza)isoindolinone-type compounds: Towards in vitro InhA action, Mycobacterium tuberculosis growth and mycolic acid biosynthesis. | 1-gen-2016 | Chollet, A; Stigliani, Jl; Pasca, MARIA ROSALIA; Mori, Giorgia; Lherbet, C; Constant, P; Quémard, A; Bernadou, J; Pratviel, G; Bernardes Génisson, V. | |
| Design, Syntheses, and Anti-TB Activity of 1,3-Benzothiazinone Azide and Click Chemistry Products Inspired by BTZ043 | 1-gen-2016 | Tiwari, R.; Miller, P. A.; Chiarelli, Laurent; Mori, Giorgia; Šarkan, M.; Centárová, I.; Cho, S.; Mikušová, K.; Franzblau, S. G.; Oliver, A. G.; Miller, M. J. | |
| Triazolophthalazines: Easily Accessible Compounds with Potent Antitubercular Activity. | 1-gen-2016 | Veau, D; Krykun, S; Mori, Giorgia; Orena, BEATRICE SILVIA; Pasca, MARIA ROSALIA; Frongia, C; Lobjois, V; Chassaing, S; Lherbet, C; Baltas, M. | |
| New and old hot drug targets in tuberculosis | 1-gen-2016 | Chiarelli, Laurent; Mori, Giorgia; Esposito, Marta; Orena, BEATRICE SILVIA; Pasca, MARIA ROSALIA | |
| New prodrugs against tuberculosis | 1-gen-2017 | Mori, Giorgia; Chiarelli, Laurent; Riccardi, Giovanna; Pasca, MARIA ROSALIA | |
| A phenotypic based target screening approach delivers new antitubercular CTP synthetase inhibitors | 1-gen-2017 | Esposito, Marta; Szadocka, Sára; Degiacomi, Giulia; Orena, BEATRICE SILVIA; Mori, Giorgia; Piano, Valentina; Boldrin, Francesca; Zemanova, Julia; Huszár, Stanislav; Barros, David; Ekins, Sean; Lelièvre, Joël; Manganelli, Riccardo; Mattevi, Andrea; Pasca, MARIA ROSALIA; Riccardi, Giovanna; Ballell, Lluis; Mikušová, Katarína; Chiarelli, Laurent | |
| Mechanochemical Synthesis and Biological Evaluation of Novel Isoniazid Derivatives with Potent Antitubercular Activity. | 1-gen-2017 | Oliveira, Pfm; Guidetti, B; Chamayou, A; André Barrès, C; Madacki, J; Korduláková, J; Mori, Giorgia; Orena, BEATRICE SILVIA; Chiarelli, Laurent; Pasca, MARIA ROSALIA; Lherbet, C; Carayon, C; Massou, S; Baron, M; Baltas, M. | |
| Discovery and development of novel salicylate synthase (MbtI) furanic inhibitors as antitubercular agents | 1-gen-2018 | Chiarelli, Laurent R; Mori, Matteo; Barlocco, Daniela; Beretta, Giangiacomo; Gelain, Arianna; Pini, Elena; Porcino, Marianna; Mori, Giorgia; Stelitano, Giovanni; Costantino, Luca; Lapillo, Margherita; Bonanni, Davide; Poli, Giulio; Tuccinardi, Tiziano; Villa, Stefania; Meneghetti, Fiorella | |
| The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase | 1-gen-2018 | Mori, G; Orena, Bs; Franch, C; Mitchenall, La; Godbole, Aa; Rodrigues, L; Aguilar-Pérez, C; Zemanová, J; Huszár, S; Forbak, M; Lane, Tr; Sabbah, M; Deboosere, N; Frita, R; Vandeputte, A; Hoffmann, E; Russo, R; Connell, N; Veilleux, C; Kumar, R; Kumar, P; Freundlich, Js; Brodin, P; Aínsa, Ja; Nagaraja, V; Maxwell, A; Mikušová, K; Pasca, Mr; Ekins, S. | |
| A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK | 1-gen-2018 | Chiarelli, L; Mori, G; Orena, Bs; Esposito, M; Lane, T; de Lopes Jesus Ribeiro, Al; Degiacomi, G; Zemanova, J; Szadocka, S; Huszar, S; Palcekova, Z; Manfredi, M; Gosetti, F; Lelievre, J; Ballell, L; Kazakova, E; Makarov, V; Marengo, E; Mikusova, K; Cole, St; Riccardi, G; Ekins, S; Pasca, Mr | |
| Shifts of Faecal Microbiota During Sporadic Colorectal Carcinogenesis | 1-gen-2018 | Mori, G; Rampelli, S; Orena, Bs; Rengucci, C; De Maio, G; Barbieri, G; Passardi, A; Casadei Gardini, A; Frassineti, Gl; Gaiarsa, S; Albertini, Am; Ranzani, Gn; Calistri, D; Pasca, Mr | |
| Gut Microbiota Analysis in Postoperative Lynch Syndrome Patients | 1-gen-2019 | Mori, G; Orena, Bs; Cultrera, I; Barbieri, G; Albertini, Am; Ranzani, Gn; Carnevali, I; Tibiletti, Mg; Pasca, Mr |
Legenda icone
- file ad accesso aperto
- file disponibili sulla rete interna
- file disponibili agli utenti autorizzati
- file disponibili solo agli amministratori
- file sotto embargo
- nessun file disponibile