IRIS

Sfoglia per Autore  

Opzioni
Mostrati risultati da 1 a 20 di 35
Titolo Data di pubblicazione Autore(i) File
Discovery and development of novel salicylate synthase (MbtI) furanic inhibitors as antitubercular agents 1-gen-2018 Chiarelli, Laurent R; Mori, Matteo; Barlocco, Daniela; Beretta, Giangiacomo; Gelain, Arianna; Pini, Elena; Porcino, Marianna; Mori, Giorgia; Stelitano, Giovanni; Costantino, Luca; Lapillo, Margherita; Bonanni, Davide; Poli, Giulio; Tuccinardi, Tiziano; Villa, Stefania; Meneghetti, Fiorella
Multi-target antitubercular drugs: identification of novel dual MbtI and MptpB inhibitors. 1-gen-2019 Mori, M; Villa, S; Chiarelli, Lr; Stelitano, G; Gelain, A; Tuccinardi, T; Bellinzoni, M.; Meneghetti, F.
Exploring the role of the heterocyclic moiety of 5-(4-nitrophenyl)-2-furoic acid, a promising inhibitor of MbtI from Mycobacterium tuberculosis. 1-gen-2019 Mori, M; Chiarelli, Lr; Stelitano, G; Gelain, A; Tuccinardi, T; Bellinzoni, M.; Meneghetti, F; Villa, S.
Structural insights for the development of novel antituberculars targeting the iron uptake pathway. 1-gen-2019 Mori, M; Villa, S; Chiarelli, Lr; Stelitano, G; Gelain, A; Tuccinardi, T; Bellinzoni, M.; Meneghetti, F
Targeting iron uptake pathway for the development of novel antitubercular drugs. 1-gen-2019 Stelitano, G; Mori, M; Sammartino, J C; Gelain, A; Tuccinardi, T; Villa, S; Meneghetti, F; Chiarelli, LAURENT ROBERT
New insight into structure-activity of furan-based salicylate synthase (MbtI) inhibitors as potential antitubercular agents 1-gen-2019 Chiarelli, Laurent R; Mori, Matteo; Beretta, Giangiacomo; Gelain, Arianna; Pini, Elena; Sammartino, Josè Camilla; Stelitano, Giovanni; Barlocco, Daniela; Costantino, Luca; Lapillo, Margherita; Poli, Giulio; Caligiuri, Isabella; Rizzolio, Flavio; Bellinzoni, Marco; Tuccinardi, Tiziano; Villa, Stefania; Meneghetti, Fiorella
Investigating the inhibition mechanism and catalytic cycle of MbtI, the salicylate synthase from Mycobacterium tuberculosis. 1-gen-2020 Mori, M.; Villa, S.; Gelain, A; Pini, E. R. E.; Stelitano, G.; Chiarelli, L. R.; Tuccinardi, T.; Bellinzoni, M.; Meneghetti, F.
A dual-target approach in anti-tuberculosis therapy: new MptpB/MbtI. 1-gen-2020 Cazzaniga, G; Mori, M; Gelain, A; Pini, E; Stelitano, G; Chiarelli, Lr; Meneghetti, F; Villa, S.
Structural and biochemical investigations into the binding mode of furan-based inhibitors of MbtI from M. tuberculosis. 1-gen-2020 Mori, M.; Villa, S.; Chiarelli, L. R.; Stelitano, G.; Gelain, A.; Tuccinardi, T.; Bellinzoni, M.; Meneghetti, F.
Multitargeting Compounds: A Promising Strategy to Overcome Multi-Drug Resistant Tuberculosis 1-gen-2020 Stelitano, Giovanni; Sammartino, José Camilla; Chiarelli, Laurent Roberto
Shedding X-ray light on the role of magnesium in the activity of M. tuberculosis salicylate synthase (MbtI) for drug design 1-gen-2020 Mori, Matteo; Stelitano, Giovanni; Gelain, Arianna; Pini, Elena; Chiarelli, Laurent R; Sammartino, Josè Camilla; Poli, Giulio; Tuccinardi, Tiziano; Beretta, Giangiacomo; Porta, Alessio; Bellinzoni, Marco; Villa, Stefania; Meneghetti, Fiorella
A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis MbtI and MPtpB 1-gen-2021 Stelitano, G; Cazzaniga, G; Mori, M; Villa, S; Meneghetti, F; Chiarelli, Lr.
Synthesis, characterization, and biological evaluation of new derivatives targeting MbtI as antitubercular agents 1-gen-2021 Mori, M.; Stelitano, G.; Chiarelli, L. R.; Cazzaniga, G.; Gelain, A.; Barlocco, D.; Pini, E.; Meneghetti, F.; Villa, S.
Structural and Activity Relationships of 6-Sulfonyl-8-Nitrobenzothiazinones as Antitubercular Agents 1-gen-2021 Fan, Dongguang; Wang, Bin; Stelitano, Giovanni; Savková, Karin; Shi, Rui; Huszár, Stanislav; Han, Quanquan; Mikušová, Katarína; Chiarelli, Laurent R; Lu, Yu; Qiao, Chunhua
Phagocyte-targeting polymersomes as intracellular delivery carriers for enzymatic inhibitors with antitubercular activity. 1-gen-2022 Cazzaniga, G; Mori, M; Meneghetti, F; Chiarelli, Lr; Stelitano, G; Di Gugliemo, C; Batalha, Il; Battaglia, G; Villa, S.
Targeting the mycobactin biosynthesis pathway in M. tuberculosis: a step towards the improvement of the anti-virulence activity of MbtI inhibitors. 1-gen-2022 Mori, M; Villa, S; Chiarelli, Lr; Stelitano, G; Gelain, A; Cazzaniga, G; Bellinzoni, M; Rizzello, L; Scarpa, E; Griego, A; Fumagalli, A; Meneghetti, F.
Polymersomes as selective drug delivery carriers for innovative anti-TB agents. 1-gen-2022 Cazzaniga, G; Mori, M; Meneghetti, F; Chiarelli, Lr; Stelitano, G; Batalha, Il; Battaglia, G; Villa, S.
The Veterinary Anti-Parasitic Selamectin Is a Novel Inhibitor of the Mycobacterium tuberculosis DprE1 Enzyme 1-gen-2022 Ezquerra-Aznarez, J. M.; Degiacomi, G.; Gasparovic, H.; Stelitano, G.; Sammartino, J. C.; Kordulakova, J.; Governa, P.; Manetti, F.; Pasca, M. R.; Chiarelli, L. R.; Ramon-Garcia, S.
Functional investigation of the antitubercular drug target Decaprenylphosphoryl-β-D-ribofuranose-2-epimerase DprE1/DprE2 complex 1-gen-2022 Sammartino, Josè Camilla; Morici, Martino; Stelitano, Giovanni; Degiacomi, Giulia; Riccardi, Giovanna; Chiarelli, Laurent Roberto
Synthesis and assessment of the in vitro and ex vivo activity of salicylate synthase (Mbti) inhibitors as new candidates for the treatment of mycobacterial infections 1-gen-2022 Mori, M; Stelitano, G; Griego, A; Chiarelli, Lr; Cazzaniga, G; Gelain, A; Pini, E; Camera, M; Canzano, P; Fumagalli, A; Scarpa, E; Cordiglieri, C; Rizzello, L; Villa, S; Meneghetti, F.
Mostrati risultati da 1 a 20 di 35
Legenda icone

  •  file ad accesso aperto
  •  file disponibili sulla rete interna
  •  file disponibili agli utenti autorizzati
  •  file disponibili solo agli amministratori
  •  file sotto embargo
  •  nessun file disponibile