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Facing the limits of the genetic algorithms for covariate selection 1-gen-2022 Ronchi, D.; Tosca, E. M.; Ravasi, I.; Bartolucci, R.; Magni, P.
First-order longitudinal population model of FEV1 data: single-trial modeling and meta-analysis 1-gen-2013 Marostica, Eleonora; S., Yang; Russu, Alberto; DE NICOLAO, Giuseppe; S., Zamuner; M., Beerahee
Global sensitivity analysis of a physiologically based pulmonary absorption model 1-gen-2019 Melillo, N.; Grandoni, S.; Cesari, N.; Brogin, G.; Puccini, P.; Magni, P.
In vitro-in vivo correlation (IVIVC) population modeling for the in silico bioequivalence of a long-acting release formulation of Progesterone 1-gen-2018 Tosca, E. M.; De Nicolao, G.; Rochetti, M.; Magni, P.; Perez, E.; Nieto, C.; Bettica, P.; Moscoso del Prado, J.
Integrating Reinforcement Learning and PK-PD modelling to enable precision dosing: a multi-objective optimization for the treatment of Polycithemia Vera patients with Givinostat 1-gen-2023 De Carlo, A.; Tosca, E. M.; Magni, P.
Integration of response, tolerability and dropout in flexible-dose trials: a case study in depression 1-gen-2011 Russu, Alberto; Marostica, Eleonora; DE NICOLAO, Giuseppe; A. C., Hooker; Poggesi, Italo; R., Gomeni; S., Zamuner
Landscape on technical and conceptual requirements in Drug/Disease Modelling & Simulation 1-gen-2012 G., Vlasakakis; E., Comets; A., Drescher; I., Gueorguieva; Magni, Paolo; Terranova, Nadia; O., Della Pasqua; E. C., de Lange; C., Kloft
Mathematical models of tumor growth inhibition in xenograft mice after administration of anticancer agents given in combination 1-gen-2013 Terranova, Nadia; Germani, MASSIMILIANO ENRICO; DEL BENE, Francesca; Magni, Paolo
Mechanistic multi-scale systems pharmacokinetics model applied for the anticancer drug Gemcitabine in pancreatic cancer 1-gen-2017 Garcia Cremades, M.; Melillo, Nicola; Magni, Paolo; Troconiz, I. F.
Methods and tools for multiscale modelling in Systems Pharmacology: a review 1-gen-2016 Borella, Elisa; Carrara, Letizia; Lavezzi, SILVIA MARIA; Massaiu, Ilaria; Sauta, Elisabetta; Tosca, ELENA MARIA; Vitali, Francesca; Zucca, Susanna; Pasotti, Lorenzo; DE NICOLAO, Giuseppe; Magni, Paolo
Model Description Language (MDL) - a standard for model communication and interoperability 1-gen-2016 Smith, Mk; Moodie, S; Bizzotto, R; Blaudez, E; Borella, Elisa; Carrara, Letizia; Chan, P; Chenel, M; Comets, E; Gieschke, R; Harling, K; Harnisch, L; Hartung, N; Hooker, A; Karlsson, Mo; Kaye, R; Kloft, C; Kokash, N; Lavielle, M; Magni, Paolo; Mari, A; Mentre, F; Muselle, C; Nordgren, R; Nyberg, H; Parra Guillen, Zp; Pasotti, Lorenzo; Rode Kristensen, N; Smith, G; Swat, Mj; Terranova, Nadia; Yvon, F; Holford, NICHOLAS HUGH GEORGE
Model-based analysis of patient-derived organoids for evaluating anticancer drugs 1-gen-2023 Ronchi, D.; Tosca, E. M.; De Siervi, S.; Turato, C.; Lolicato, M. G.; Magni, P.
A model-based approach to extrapolate drug-drug interactions from rats to humans 1-gen-2017 Piana, C.; Mazzei, P.; Smania, Giovanni; Magni, Paolo; Lecci, A.; Capriati, A.; Pellacani, A.
Model-based comparison of alternative study designs in paediatric trials 1-gen-2015 Smania, Giovanni; Baiardi, P.; Cella, M.; Magni, Paolo
Modelling of protozoa dynamics and drug effects in a murine model of malaria infection 1-gen-2012 Terranova, Nadia; M. B., Jimenez Diaz; I., Angulo Barturen; Magni, Paolo; O., Della Pasqua
Modelling the effect of Sunitinib given alone and in combination with CPT-11 on the tumor growth in xenografted mice 1-gen-2015 Carrara, Letizia; Ribba, B.; Tod, M.; Wei, M.; You, B.; Freyer, G.; Magni, Paolo
Multiscale mechanistic models in Systems Pharmacology: development of a model describing Atorvastatin pharmacokinetics through integration of metabolic network in Physiologically Based Pharmacokinetic models 1-gen-2017 Melillo, Nicola; Pasotti, Lorenzo; Magni, Paolo
Optimal design for informative protocols in xenograft tumor growth inhibition models 1-gen-2015 Lestini, Giulia; Mentré, F.; Magni, Paolo
Optimal design of paediatric clinical trials: the Macitentan case study 1-gen-2019 Bartolucci, R.; Magni, P.
Paediatric trial design optimization using prior knowledge in combination with modelling & simulations 1-gen-2017 Borella, Elisa; Oosterholt, S.; Magni, Paolo; Della Pasqua, O.
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