Sfoglia per Rivista PAGE
Global sensitivity analysis of a physiologically based pulmonary absorption model
2019-01-01 Melillo, N.; Grandoni, S.; Cesari, N.; Brogin, G.; Puccini, P.; Magni, P.
Impact of sampling procedure on individual pharmacokinetic parameter estimation methods
2024-01-01 Cuquerella-Gilabert, M.; Sanchez Herrero, S.; Merino Sanjuan, M.; Tosca, E. M.; Mangas Sanjuan, V.; Magni, P.
In vitro-in vivo correlation (IVIVC) population modeling for the in silico bioequivalence of a long-acting release formulation of Progesterone
2018-01-01 Tosca, E. M.; De Nicolao, G.; Rochetti, M.; Magni, P.; Perez, E.; Nieto, C.; Bettica, P.; Moscoso del Prado, J.
Integrating Reinforcement Learning and PK-PD modelling to enable precision dosing: a multi-objective optimization for the treatment of Polycithemia Vera patients with Givinostat
2023-01-01 De Carlo, A.; Tosca, E. M.; Magni, P.
Integration of response, tolerability and dropout in flexible-dose trials: a case study in depression
2011-01-01 Russu, Alberto; Marostica, Eleonora; DE NICOLAO, Giuseppe; A. C., Hooker; Poggesi, Italo; R., Gomeni; S., Zamuner
Landscape on technical and conceptual requirements in Drug/Disease Modelling & Simulation
2012-01-01 G., Vlasakakis; E., Comets; A., Drescher; I., Gueorguieva; Magni, Paolo; Terranova, Nadia; O., Della Pasqua; E. C., de Lange; C., Kloft
Mathematical models of tumor growth inhibition in xenograft mice after administration of anticancer agents given in combination
2013-01-01 Terranova, Nadia; Germani, MASSIMILIANO ENRICO; DEL BENE, Francesca; Magni, Paolo
Mechanistic multi-scale systems pharmacokinetics model applied for the anticancer drug Gemcitabine in pancreatic cancer
2017-01-01 Garcia Cremades, M.; Melillo, Nicola; Magni, Paolo; Troconiz, I. F.
Methods and tools for multiscale modelling in Systems Pharmacology: a review
2016-01-01 Borella, Elisa; Carrara, Letizia; Lavezzi, SILVIA MARIA; Massaiu, Ilaria; Sauta, Elisabetta; Tosca, ELENA MARIA; Vitali, Francesca; Zucca, Susanna; Pasotti, Lorenzo; DE NICOLAO, Giuseppe; Magni, Paolo
Model Description Language (MDL) - a standard for model communication and interoperability
2016-01-01 Smith, Mk; Moodie, S; Bizzotto, R; Blaudez, E; Borella, Elisa; Carrara, Letizia; Chan, P; Chenel, M; Comets, E; Gieschke, R; Harling, K; Harnisch, L; Hartung, N; Hooker, A; Karlsson, Mo; Kaye, R; Kloft, C; Kokash, N; Lavielle, M; Magni, Paolo; Mari, A; Mentre, F; Muselle, C; Nordgren, R; Nyberg, H; Parra Guillen, Zp; Pasotti, Lorenzo; Rode Kristensen, N; Smith, G; Swat, Mj; Terranova, Nadia; Yvon, F; Holford, NICHOLAS HUGH GEORGE
Model-based analysis of patient-derived organoids for evaluating anticancer drugs
2023-01-01 Ronchi, D.; Tosca, E. M.; De Siervi, S.; Turato, C.; Lolicato, M. G.; Magni, P.
A model-based approach to extrapolate drug-drug interactions from rats to humans
2017-01-01 Piana, C.; Mazzei, P.; Smania, Giovanni; Magni, Paolo; Lecci, A.; Capriati, A.; Pellacani, A.
Model-based comparison of alternative study designs in paediatric trials
2015-01-01 Smania, Giovanni; Baiardi, P.; Cella, M.; Magni, Paolo
Modeling tumor growth inhibition in Glioblastoma spheroids after exposure to RC-106, a novel sigma receptors modulator
2024-01-01 Aiello, L.; Tosca, E. M.; Ronchi, D.; Ceccarelli, G.; Listro, R.; Collina, S.; Magni, P.
Modelling of protozoa dynamics and drug effects in a murine model of malaria infection
2012-01-01 Terranova, Nadia; M. B., Jimenez Diaz; I., Angulo Barturen; Magni, Paolo; O., Della Pasqua
Modelling the effect of Sunitinib given alone and in combination with CPT-11 on the tumor growth in xenografted mice
2015-01-01 Carrara, Letizia; Ribba, B.; Tod, M.; Wei, M.; You, B.; Freyer, G.; Magni, Paolo
Multiscale mechanistic models in Systems Pharmacology: development of a model describing Atorvastatin pharmacokinetics through integration of metabolic network in Physiologically Based Pharmacokinetic models
2017-01-01 Melillo, Nicola; Pasotti, Lorenzo; Magni, Paolo
Optimal design for informative protocols in xenograft tumor growth inhibition models
2015-01-01 Lestini, Giulia; Mentré, F.; Magni, Paolo
Optimal design of paediatric clinical trials: the Macitentan case study
2019-01-01 Bartolucci, R.; Magni, P.
Paediatric trial design optimization using prior knowledge in combination with modelling & simulations
2017-01-01 Borella, Elisa; Oosterholt, S.; Magni, Paolo; Della Pasqua, O.
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
Global sensitivity analysis of a physiologically based pulmonary absorption model | 1-gen-2019 | Melillo, N.; Grandoni, S.; Cesari, N.; Brogin, G.; Puccini, P.; Magni, P. | |
Impact of sampling procedure on individual pharmacokinetic parameter estimation methods | 1-gen-2024 | Cuquerella-Gilabert, M.; Sanchez Herrero, S.; Merino Sanjuan, M.; Tosca, E. M.; Mangas Sanjuan, V.; Magni, P. | |
In vitro-in vivo correlation (IVIVC) population modeling for the in silico bioequivalence of a long-acting release formulation of Progesterone | 1-gen-2018 | Tosca, E. M.; De Nicolao, G.; Rochetti, M.; Magni, P.; Perez, E.; Nieto, C.; Bettica, P.; Moscoso del Prado, J. | |
Integrating Reinforcement Learning and PK-PD modelling to enable precision dosing: a multi-objective optimization for the treatment of Polycithemia Vera patients with Givinostat | 1-gen-2023 | De Carlo, A.; Tosca, E. M.; Magni, P. | |
Integration of response, tolerability and dropout in flexible-dose trials: a case study in depression | 1-gen-2011 | Russu, Alberto; Marostica, Eleonora; DE NICOLAO, Giuseppe; A. C., Hooker; Poggesi, Italo; R., Gomeni; S., Zamuner | |
Landscape on technical and conceptual requirements in Drug/Disease Modelling & Simulation | 1-gen-2012 | G., Vlasakakis; E., Comets; A., Drescher; I., Gueorguieva; Magni, Paolo; Terranova, Nadia; O., Della Pasqua; E. C., de Lange; C., Kloft | |
Mathematical models of tumor growth inhibition in xenograft mice after administration of anticancer agents given in combination | 1-gen-2013 | Terranova, Nadia; Germani, MASSIMILIANO ENRICO; DEL BENE, Francesca; Magni, Paolo | |
Mechanistic multi-scale systems pharmacokinetics model applied for the anticancer drug Gemcitabine in pancreatic cancer | 1-gen-2017 | Garcia Cremades, M.; Melillo, Nicola; Magni, Paolo; Troconiz, I. F. | |
Methods and tools for multiscale modelling in Systems Pharmacology: a review | 1-gen-2016 | Borella, Elisa; Carrara, Letizia; Lavezzi, SILVIA MARIA; Massaiu, Ilaria; Sauta, Elisabetta; Tosca, ELENA MARIA; Vitali, Francesca; Zucca, Susanna; Pasotti, Lorenzo; DE NICOLAO, Giuseppe; Magni, Paolo | |
Model Description Language (MDL) - a standard for model communication and interoperability | 1-gen-2016 | Smith, Mk; Moodie, S; Bizzotto, R; Blaudez, E; Borella, Elisa; Carrara, Letizia; Chan, P; Chenel, M; Comets, E; Gieschke, R; Harling, K; Harnisch, L; Hartung, N; Hooker, A; Karlsson, Mo; Kaye, R; Kloft, C; Kokash, N; Lavielle, M; Magni, Paolo; Mari, A; Mentre, F; Muselle, C; Nordgren, R; Nyberg, H; Parra Guillen, Zp; Pasotti, Lorenzo; Rode Kristensen, N; Smith, G; Swat, Mj; Terranova, Nadia; Yvon, F; Holford, NICHOLAS HUGH GEORGE | |
Model-based analysis of patient-derived organoids for evaluating anticancer drugs | 1-gen-2023 | Ronchi, D.; Tosca, E. M.; De Siervi, S.; Turato, C.; Lolicato, M. G.; Magni, P. | |
A model-based approach to extrapolate drug-drug interactions from rats to humans | 1-gen-2017 | Piana, C.; Mazzei, P.; Smania, Giovanni; Magni, Paolo; Lecci, A.; Capriati, A.; Pellacani, A. | |
Model-based comparison of alternative study designs in paediatric trials | 1-gen-2015 | Smania, Giovanni; Baiardi, P.; Cella, M.; Magni, Paolo | |
Modeling tumor growth inhibition in Glioblastoma spheroids after exposure to RC-106, a novel sigma receptors modulator | 1-gen-2024 | Aiello, L.; Tosca, E. M.; Ronchi, D.; Ceccarelli, G.; Listro, R.; Collina, S.; Magni, P. | |
Modelling of protozoa dynamics and drug effects in a murine model of malaria infection | 1-gen-2012 | Terranova, Nadia; M. B., Jimenez Diaz; I., Angulo Barturen; Magni, Paolo; O., Della Pasqua | |
Modelling the effect of Sunitinib given alone and in combination with CPT-11 on the tumor growth in xenografted mice | 1-gen-2015 | Carrara, Letizia; Ribba, B.; Tod, M.; Wei, M.; You, B.; Freyer, G.; Magni, Paolo | |
Multiscale mechanistic models in Systems Pharmacology: development of a model describing Atorvastatin pharmacokinetics through integration of metabolic network in Physiologically Based Pharmacokinetic models | 1-gen-2017 | Melillo, Nicola; Pasotti, Lorenzo; Magni, Paolo | |
Optimal design for informative protocols in xenograft tumor growth inhibition models | 1-gen-2015 | Lestini, Giulia; Mentré, F.; Magni, Paolo | |
Optimal design of paediatric clinical trials: the Macitentan case study | 1-gen-2019 | Bartolucci, R.; Magni, P. | |
Paediatric trial design optimization using prior knowledge in combination with modelling & simulations | 1-gen-2017 | Borella, Elisa; Oosterholt, S.; Magni, Paolo; Della Pasqua, O. |
Legenda icone
- file ad accesso aperto
- file disponibili sulla rete interna
- file disponibili agli utenti autorizzati
- file disponibili solo agli amministratori
- file sotto embargo
- nessun file disponibile