SITA-SWAP and SITA-SAP in glaucoma suspects

Purpose To compare the ability of Standard and Short-Wavelength Automated Perimetry to point out early functional defects in glaucoma suspects picked up using imaging tests such as GDx-VCC and HRT-III Methods Randomly selected 90 eyes of 90 patients screened on the basis of clinical suspicion of having early glaucoma, were submitted to a complete ophthalmic examination including GDx and HRT. Moorfields regression analysis(MRA), cup shape measure (CSM), rim area (RA) for HRT-III and nerve fiber indicator (NFI), superior and inferior TSNIT average for GDx-VCC were taken into account. If at least one of the parameters was found out of the normal limits, a 24-2 SITA-SAP and SITA-SWAP tests. Mean defect (MD), pattern standard deviation (PSD), number of points significantly depressed <5% and <1% in the pattern deviation plot and test duration for SAP and SWAP were compared using the Wilcoxon signed rank test and Bland and Altman plot. Media opacities >1 according to LOCS-III were excluded Results According to the results of the Wilcoxon test SWAP gave a significantly larger MD and PSD defect than SAP (p<0.01) and a larger number of depressed points with p<1%(p<0.01). SWAP test duration was shorter than SAP(p<0.01). These results were not confirmed by Bland and Altman plot that could not point out significant differences between the parameters provided by SWAP and SAP Conclusion In patients with suspicion of early glaucomatous damage given by imaging techniques (GDx-VCC and HRT-III), SITA-SWAP is not able to identify a functional loss in all cases. The SITA applied to SWAP can improve the ability of the perimetric test to pick up early defects involving short-wavelength sensitive ganglion cells at least in some patients and in a shorter test time than SITA-SAP