TRAVELLI, CRISTINA

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TRAVELLI, CRISTINA

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DIPARTIMENTO DI SCIENZE DEL FARMACO

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A nicotinamide phosphoribosyltransferase–GAPDH interaction sustains the stress-induced NMN/NAD+ salvage pathway in the nucleus

2020-01-01 Grolla, A. A.; Miggiano, R.; Marino, D. D.; Bianchi, M.; Gori, A.; Orsomando, G.; Gaudino, F.; Galli, U.; Grosso, E. D.; Mazzola, F.; Angeletti, C.; Guarneri, M.; Torretta, S.; Calabro, M.; Boumya, S.; Fan, X.; Colombo, G.; Travelli, C.; Rocchio, F.; Aronica, E.; Wohlschlegel, J. A.; Deaglio, S.; Rizzi, M.; Genazzani, A. A.; Garavaglia, S.

A novel potent nicotinamide phosphoribosyltransferase inhibitor synthesized via click chemistry

2010-01-01 Colombano, G.; Travelli, C.; Galli, U.; Caldarelli, A.; Chini, M. G.; Canonico, P. L.; Sorba, G.; Bifulco, G.; Tron, G. C.; Genazzani, A. A.

Autophagy and inflammation an intricate affair in the management of obesity and metabolic disorders: evidence for novel pharmacological strategies?

2024-01-01 Friuli, M.; Sepe, C.; Panza, E.; Travelli, C.; Paterniti, I.; Romano, A.

Characterization of NAD uptake in mammalian cells

2008-01-01 Billington, R. A.; Travelli, C.; Ercolano, E.; Galli, U.; Roman, C. B.; Grolla, A. A.; Canonico, P. L.; Condorelli, F.; Genazzani, A. A.

Data on metabolic stability, aqueous solubility and CYP inhibition of novel triazole-based nicotinamide phosphoribosyltransferase (NAMPT) inhibitors

2020-01-01 Aprile, S.; Galli, U.; Tron, G. C.; Del Grosso, E.; Travelli, C.; Grosa, G.

Design, synthesis, and biological evaluation of combretabenzodiazepines: A novel class of anti-tubulin agents

2015-01-01 Galli, U.; Travelli, C.; Aprile, S.; Arrigoni, E.; Torretta, S.; Grosa, G.; Massarotti, A.; Sorba, G.; Canonico, P. L.; Genazzani, A. A.; Tron, G. C.

Discovery of Highly Potent Benzimidazole Derivatives as Indoleamine 2,3-Dioxygenase-1 (IDO1) Inhibitors: From Structure-Based Virtual Screening to in Vivo Pharmacodynamic Activity

2020-01-01 Serafini, M.; Torre, E.; Aprile, S.; Grosso, E. D.; Gesu, A.; Griglio, A.; Colombo, G.; Travelli, C.; Paiella, S.; Adamo, A.; Orecchini, E.; Coletti, A.; Pallotta, M. T.; Ugel, S.; Massarotti, A.; Pirali, T.; Fallarini, S.

eNAMPT/TLR4 inflammatory cascade activation is a key contributor to SLE Lung vasculitis and alveolar hemorrhage

2023-01-01 Tumurkhuu, Gantsetseg; Casanova, Nancy G.; Kempf, Carrie L.; Ercan Laguna, Duygu; Camp, Sara M.; Dagvadorj, Jargalsaikhan; Song, Jin H.; Reyes Hernon, Vivian; Travelli, Cristina; Montano, Erica N.; Yu, Jeong Min; Ishimori, Mariko; Wallace, Daniel J.; Sammani, Saad; Jefferies, Caroline; Garcia, Joe G. N.

Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) neutralization counteracts T cell immune evasion in breast cancer

2023-01-01 Travelli, C.; Colombo, G.; Aliotta, M.; Fagiani, F.; Fava, N.; De Sanctis, R.; Grolla, A. A.; Garcia, J. G. N.; Clemente, N.; Portararo, P.; Costanza, M.; Condorelli, F.; Colombo, M. P.; Sangaletti, S.; Genazzani, A. A.

Extracellular nicotinamide phosphoribosyltransferase boosts IFNγ-induced macrophage polarization independently of TLR4

2022-01-01 Colombo, G.; Travelli, C.; Porta, C.; Genazzani, A. A.

Extracellular nicotinamide phosphoribosyltransferase, a new cancer metabokine

2016-01-01 Grolla, A. A.; Travelli, C.; Genazzani, A. A.; Sethi, J. K.

Identification of a novel NAMPT inhibitor by combinatorial click chemistry and chemical refinement

2015-01-01 Theeramunkong, S.; Galli, U.; Grolla, A. A.; Caldarelli, A.; Travelli, C.; Massarotti, A.; Troiani, M. P.; Alisi, M. A.; Orsomando, G.; Genazzani, A. A.; Tron, G. C.

Identification of novel aza-analogs of TN-16 as disrupters of microtubule dynamics through a multicomponent reaction

2023-01-01 Foroutan, A.; Corazzari, M.; Grolla, A. A.; Colombo, G.; Travelli, C.; Genazzani, A. A.; Theeramunkong, S.; Galli, U.; Tron, G. C.

Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity

2017-01-01 Travelli, C.; Aprile, S.; Rahimian, R.; Grolla, A. A.; Rogati, F.; Bertolotti, M.; Malagnino, F.; Di Paola, R.; Impellizzeri, D.; Fusco, R.; Mercalli, V.; Massarotti, A.; Stortini, G.; Terrazzino, S.; Del Grosso, E.; Fakhfouri, G.; Troiani, M. P.; Alisi, M. A.; Grosa, G.; Sorba, G.; Canonico, P. L.; Orsomando, G.; Cuzzocrea, S.; Genazzani, A. A.; Galli, U.; Tron, G. C.

Identification of potent triazolylpyridine nicotinamide phosphoribosyltransferase (NAMPT) inhibitors bearing a 1,2,3-triazole tail group

2019-01-01 Travelli, C.; Aprile, S.; Mattoteia, D.; Colombo, G.; Clemente, N.; Scanziani, E.; Terrazzino, S.; Alisi, M. A.; Polenzani, L.; Grosa, G.; Genazzani, A. A.; Tron, G. C.; Galli, U.

Increased plasma nicotinamide phosphoribosyltransferase is associated with a hyperproliferative phenotype and restrains disease progression in MPN-associated myelofibrosis

2016-01-01 Rosti, V.; Campanelli, R.; Massa, M.; Viarengo, G.; Villani, L.; Poletto, V.; Bonetti, E.; Catarsi, P.; Magrini, U.; Grolla, A. A.; Travelli, C.; Genazzani, A. A.; Barosi, G.

Insight Into Nicotinamide Adenine Dinucleotide Homeostasis as a Targetable Metabolic Pathway in Colorectal Cancer

2021-01-01 Colombo, G.; Gelardi, E. L. M.; Balestrero, F. C.; Moro, M.; Travelli, C.; Genazzani, A. A.

Involvement of eNAMPT/TLR4 inflammatory signaling in progression of non-alcoholic fatty liver disease, steatohepatitis, and fibrosis

2023-01-01 Sun, B. L.; Sun, X.; Kempf, C. L.; Song, J. H.; Casanova, N. G.; Camp, S. M.; Reyeshernon, V.; Fallon, M.; Bime, C.; Martin, D. R.; Travelli, C.; Zhang, D. D.; Garcia, J.

Medicinal chemistry of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors

2013-01-01 Galli, U.; Travelli, C.; Massarotti, A.; Fakhfouri, G.; Rahimian, R.; Tron, G. C.; Genazzani, A. A.

Metabolic regulation of suppressive myeloid cells in cancer

2017-01-01 Sica, A.; Strauss, L.; Consonni, F. M.; Travelli, C.; Genazzani, A.; Porta, C.

Titolo	Data di pubblicazione	Autore(i)
A nicotinamide phosphoribosyltransferase–GAPDH interaction sustains the stress-induced NMN/NAD+ salvage pathway in the nucleus	1-gen-2020	Grolla, A. A.; Miggiano, R.; Marino, D. D.; Bianchi, M.; Gori, A.; Orsomando, G.; Gaudino, F.; Galli, U.; Grosso, E. D.; Mazzola, F.; Angeletti, C.; Guarneri, M.; Torretta, S.; Calabro, M.; Boumya, S.; Fan, X.; Colombo, G.; Travelli, C.; Rocchio, F.; Aronica, E.; Wohlschlegel, J. A.; Deaglio, S.; Rizzi, M.; Genazzani, A. A.; Garavaglia, S.
A novel potent nicotinamide phosphoribosyltransferase inhibitor synthesized via click chemistry	1-gen-2010	Colombano, G.; Travelli, C.; Galli, U.; Caldarelli, A.; Chini, M. G.; Canonico, P. L.; Sorba, G.; Bifulco, G.; Tron, G. C.; Genazzani, A. A.
Autophagy and inflammation an intricate affair in the management of obesity and metabolic disorders: evidence for novel pharmacological strategies?	1-gen-2024	Friuli, M.; Sepe, C.; Panza, E.; Travelli, C.; Paterniti, I.; Romano, A.
Characterization of NAD uptake in mammalian cells	1-gen-2008	Billington, R. A.; Travelli, C.; Ercolano, E.; Galli, U.; Roman, C. B.; Grolla, A. A.; Canonico, P. L.; Condorelli, F.; Genazzani, A. A.
Data on metabolic stability, aqueous solubility and CYP inhibition of novel triazole-based nicotinamide phosphoribosyltransferase (NAMPT) inhibitors	1-gen-2020	Aprile, S.; Galli, U.; Tron, G. C.; Del Grosso, E.; Travelli, C.; Grosa, G.
Design, synthesis, and biological evaluation of combretabenzodiazepines: A novel class of anti-tubulin agents	1-gen-2015	Galli, U.; Travelli, C.; Aprile, S.; Arrigoni, E.; Torretta, S.; Grosa, G.; Massarotti, A.; Sorba, G.; Canonico, P. L.; Genazzani, A. A.; Tron, G. C.
Discovery of Highly Potent Benzimidazole Derivatives as Indoleamine 2,3-Dioxygenase-1 (IDO1) Inhibitors: From Structure-Based Virtual Screening to in Vivo Pharmacodynamic Activity	1-gen-2020	Serafini, M.; Torre, E.; Aprile, S.; Grosso, E. D.; Gesu, A.; Griglio, A.; Colombo, G.; Travelli, C.; Paiella, S.; Adamo, A.; Orecchini, E.; Coletti, A.; Pallotta, M. T.; Ugel, S.; Massarotti, A.; Pirali, T.; Fallarini, S.
eNAMPT/TLR4 inflammatory cascade activation is a key contributor to SLE Lung vasculitis and alveolar hemorrhage	1-gen-2023	Tumurkhuu, Gantsetseg; Casanova, Nancy G.; Kempf, Carrie L.; Ercan Laguna, Duygu; Camp, Sara M.; Dagvadorj, Jargalsaikhan; Song, Jin H.; Reyes Hernon, Vivian; Travelli, Cristina; Montano, Erica N.; Yu, Jeong Min; Ishimori, Mariko; Wallace, Daniel J.; Sammani, Saad; Jefferies, Caroline; Garcia, Joe G. N.
Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) neutralization counteracts T cell immune evasion in breast cancer	1-gen-2023	Travelli, C.; Colombo, G.; Aliotta, M.; Fagiani, F.; Fava, N.; De Sanctis, R.; Grolla, A. A.; Garcia, J. G. N.; Clemente, N.; Portararo, P.; Costanza, M.; Condorelli, F.; Colombo, M. P.; Sangaletti, S.; Genazzani, A. A.
Extracellular nicotinamide phosphoribosyltransferase boosts IFNγ-induced macrophage polarization independently of TLR4	1-gen-2022	Colombo, G.; Travelli, C.; Porta, C.; Genazzani, A. A.
Extracellular nicotinamide phosphoribosyltransferase, a new cancer metabokine	1-gen-2016	Grolla, A. A.; Travelli, C.; Genazzani, A. A.; Sethi, J. K.
Identification of a novel NAMPT inhibitor by combinatorial click chemistry and chemical refinement	1-gen-2015	Theeramunkong, S.; Galli, U.; Grolla, A. A.; Caldarelli, A.; Travelli, C.; Massarotti, A.; Troiani, M. P.; Alisi, M. A.; Orsomando, G.; Genazzani, A. A.; Tron, G. C.
Identification of novel aza-analogs of TN-16 as disrupters of microtubule dynamics through a multicomponent reaction	1-gen-2023	Foroutan, A.; Corazzari, M.; Grolla, A. A.; Colombo, G.; Travelli, C.; Genazzani, A. A.; Theeramunkong, S.; Galli, U.; Tron, G. C.
Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity	1-gen-2017	Travelli, C.; Aprile, S.; Rahimian, R.; Grolla, A. A.; Rogati, F.; Bertolotti, M.; Malagnino, F.; Di Paola, R.; Impellizzeri, D.; Fusco, R.; Mercalli, V.; Massarotti, A.; Stortini, G.; Terrazzino, S.; Del Grosso, E.; Fakhfouri, G.; Troiani, M. P.; Alisi, M. A.; Grosa, G.; Sorba, G.; Canonico, P. L.; Orsomando, G.; Cuzzocrea, S.; Genazzani, A. A.; Galli, U.; Tron, G. C.
Identification of potent triazolylpyridine nicotinamide phosphoribosyltransferase (NAMPT) inhibitors bearing a 1,2,3-triazole tail group	1-gen-2019	Travelli, C.; Aprile, S.; Mattoteia, D.; Colombo, G.; Clemente, N.; Scanziani, E.; Terrazzino, S.; Alisi, M. A.; Polenzani, L.; Grosa, G.; Genazzani, A. A.; Tron, G. C.; Galli, U.
Increased plasma nicotinamide phosphoribosyltransferase is associated with a hyperproliferative phenotype and restrains disease progression in MPN-associated myelofibrosis	1-gen-2016	Rosti, V.; Campanelli, R.; Massa, M.; Viarengo, G.; Villani, L.; Poletto, V.; Bonetti, E.; Catarsi, P.; Magrini, U.; Grolla, A. A.; Travelli, C.; Genazzani, A. A.; Barosi, G.
Insight Into Nicotinamide Adenine Dinucleotide Homeostasis as a Targetable Metabolic Pathway in Colorectal Cancer	1-gen-2021	Colombo, G.; Gelardi, E. L. M.; Balestrero, F. C.; Moro, M.; Travelli, C.; Genazzani, A. A.
Involvement of eNAMPT/TLR4 inflammatory signaling in progression of non-alcoholic fatty liver disease, steatohepatitis, and fibrosis	1-gen-2023	Sun, B. L.; Sun, X.; Kempf, C. L.; Song, J. H.; Casanova, N. G.; Camp, S. M.; Reyeshernon, V.; Fallon, M.; Bime, C.; Martin, D. R.; Travelli, C.; Zhang, D. D.; Garcia, J.
Medicinal chemistry of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors	1-gen-2013	Galli, U.; Travelli, C.; Massarotti, A.; Fakhfouri, G.; Rahimian, R.; Tron, G. C.; Genazzani, A. A.
Metabolic regulation of suppressive myeloid cells in cancer	1-gen-2017	Sica, A.; Strauss, L.; Consonni, F. M.; Travelli, C.; Genazzani, A.; Porta, C.