The present invention relates to a mutation of the catalytic domain of a NADPH oxidase (NOX) and the use thereof to facilitate crystal structure determination, and to the corresponding mutated form of NOX and the use thereof to design and produce chemical scaffolds for the generation of NOX ligands effective in different diseases.
MUTATED FORM OF NADPH OXIDASES
MATTEVI Andrea;NENCI Simone;MAGNANI Francesca
2016-01-01
Abstract
The present invention relates to a mutation of the catalytic domain of a NADPH oxidase (NOX) and the use thereof to facilitate crystal structure determination, and to the corresponding mutated form of NOX and the use thereof to design and produce chemical scaffolds for the generation of NOX ligands effective in different diseases.File in questo prodotto:
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