The present invention is based on the finding that a camelid single domain antibody (sdAb) can be engineered for providing it with asparaginolytic activity; the obtained sdASNase molecule proved to be unexpectedly active and stable and could be targeted onto cancer cells by an antibody.

Targeted single domain antibodies with catalytic activity (T-CAN)

Claudia Scotti
;
Maristella Maggi
2018-01-01

Abstract

The present invention is based on the finding that a camelid single domain antibody (sdAb) can be engineered for providing it with asparaginolytic activity; the obtained sdASNase molecule proved to be unexpectedly active and stable and could be targeted onto cancer cells by an antibody.
2018
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/1294766
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