The subject of the present invention are cyclic compounds, in particular having azabicycloalkane structures of general formula (I) a process for their preparation, and their use as intermediates in the synthesis of biologically active peptidomimetic compounds containing the sequence RGD (Arg-Gly-Asp).

PEPTIDO-MIMETIC COMPOUNDS CONTAINING RGD SEQUENCE USEFUL AS INTEGRIN INHIBITORS

COLOMBO, LINO;DI GIACOMO, MARCELLO
2004-01-01

Abstract

The subject of the present invention are cyclic compounds, in particular having azabicycloalkane structures of general formula (I) a process for their preparation, and their use as intermediates in the synthesis of biologically active peptidomimetic compounds containing the sequence RGD (Arg-Gly-Asp).
2004
The Organic Chemistry/Polymer Science category includes resources concerned with the related fields of organic chemistry and polymer science. The organic chemistry resources deal with compounds of carbon with the exception of certain simple ones, such as the carbon oxides, carbonates, cyanides and cyanates (see Inorganic & Nuclear Chemistry). This category includes research on synthetic and natural organic compounds that may include other elements, such as hydrogen and oxygen, but also nitrogen, halogens, sulphur and phosphorous. Resources concerned with hydrocarbons, organic compounds containing only the elements carbon and hydrogen, are also included in this category. Examples are the alkanes, alkenes, alkynes and aromatics, such as benzene and naphthalene. Polymer science includes all resources dealing with the study, production and technology of polymers, which are compounds composed of very large molecules made up of repeating molecular units (monomers). Polymers may be natural substances, such as polysaccharides or proteins, or synthetic materials, such as nylon or polyethylene.
WO2005007654
Università Degli Studi di Milano
integrin; integrin inhibitors; cyclic compounds; azabicycloalkane; peptido-mimetic compounds; RGD
Tematica Ex SIR: metodica generale per la sintesi di lattami biciclici, mimetici dell?unit` i, i+1 di reverse turns (Classif. Ex SIR:Brevetto Italiano ) Brevetto depositato il 18 luglio 2003 (MI2003A 001476)
6 Brevetti::6.1 Brevetto
none
Scolastico, Carlo; Colombo, Lino; Manzoni, Leonardo; Colombo, Matteo; DI GIACOMO, Marcello
info:eu-repo/semantics/patent
285
5
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/15814
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