By combining the same active ingredient in a form which is readily soluble in water or aqueous liquids and in a delayed and programmable release form in the same solid pharmaceutical form for oral administration, preferably in the form of a double-layered tablet, high plasma levels are obtained immediately after administration which lead to a consequently rapid therapeutic effect and the maintenance of high plasma levels over a prolonged period after administration. The two forms of active ingredient are accompanied by suitable adjuvants and excipients which are capable of causing the rapid disintegration of the layer containing the active ingredient in a readily soluble form and the delayed release of the active ingredient in the delayed release form.

Solid pharmaceutical form for oral useComprising combined rapid and slow release layers

CONTE, UBALDO;MAGGI, LAURETTA;
1995-01-01

Abstract

By combining the same active ingredient in a form which is readily soluble in water or aqueous liquids and in a delayed and programmable release form in the same solid pharmaceutical form for oral administration, preferably in the form of a double-layered tablet, high plasma levels are obtained immediately after administration which lead to a consequently rapid therapeutic effect and the maintenance of high plasma levels over a prolonged period after administration. The two forms of active ingredient are accompanied by suitable adjuvants and excipients which are capable of causing the rapid disintegration of the layer containing the active ingredient in a readily soluble form and the delayed release of the active ingredient in the delayed release form.
1995
Chemistry & Analysis covers research on natural and laboratory syntheses, chemical structure, structure-function relationship, isolation and analyses of biologically significant molecules, medicinal and food chemistry. Technical material describing crucial chemical methods in biochemical analysis and research is also placed in this category. Resources covering general biochemistry and natural metabolic pathways are excluded.
EP833618B1
Lauretta Maggi
ELETTRONICO
Inglese
Internazionale
SOLID PHARMACEUTICAL FORM; ORAL USE; RAPID AND SLOW RELEASE
Patent granted by European patent Office and also in the following countries: EP0833618 (B1) WO9641617 (A1) PT833618 (E) ITMI951223 (A1) ES2174073 (T3) DE69620606 (T2) CA2224267 (A1) AT215816 (T)
6 Brevetti::6.1 Brevetto
none
Conte, Ubaldo; Maggi, Lauretta; Reiner, Alberto
info:eu-repo/semantics/patent
285
3
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/202460
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