Sfoglia per Autore
Promiscuous Targets for Antitubercular Drug Discovery: The Paradigm of DprE1 and MmpL3
2020-01-01 Degiacomi, Giulia; Belardinelli, Juan Manuel; Pasca, Maria Rosalia; De Rossi, Edda; Riccardi, Giovanna; Chiarelli, Laurent R
First triclosan-based macrocyclic inhibitors of InhA enzyme
2020-01-01 Rodriguez, F; Saffon, N; Sammartino, Jc; Degiacomi, G; Pasca, Mr; Lherbet, C.
Rv0579 Is Involved in the Resistance to the TP053 Antitubercular Prodrug
2020-01-01 Mori, G; Silvia Orena, B; Chiarelli, Lr; Degiacomi, G; Riabova, O; Sammartino, Jc; Makarov, V; Riccardi, G; Pasca, M
Design and Synthesis of Pyrano[3,2-b]indolones Showing Antimycobacterial Activity
2021-01-01 Monakhova, N.; Kordulakova, J.; Vocat, A.; Egorova, A.; Lepioshkin, A.; Salina, E. G.; Nosek, J.; Repkova, E.; Zemanova, J.; Jurdakova, H.; Gorova, R.; Roh, J.; Degiacomi, G.; Sammartino, J. C.; Pasca, M. R.; Cole, S. T.; Mikusova, K.; Makarov, V.
Age-related changes in PD-1 expression coincide with increased cytotoxic potential in Vδ2 T cells during infancy
2021-01-01 Hsu, H.; Boudova, S.; Mvula, G.; Divala, T. H.; Rach, D.; Mungwira, R. G.; Boldrin, F.; Degiacomi, G.; Manganelli, R.; Laufer, M. K.; Cairo, C.
The antimalarial mefloquine shows activity against mycobacterium abscessus, inhibiting mycolic acid metabolism
2021-01-01 Degiacomi, G.; Chiarelli, L. R.; Recchia, D.; Petricci, E.; Gianibbi, B.; Fiscarelli, E. V.; Fattorini, L.; Manetti, F.; Pasca, M. R.
A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in Mycobacterium tuberculosis
2021-01-01 Farjallah, Asma; Chiarelli, Laurent R; Forbak, Martin; Degiacomi, Giulia; Danel, Mathieu; Goncalves, Fernanda; Carayon, Chantal; Seguin, Cendrine; Fumagalli, Marco; Záhorszká, Monika; Vega, Elodie; Abid, Souhir; Grzegorzewicz, Anna; Jackson, Mary; Peixoto, Antonio; Korduláková, Jana; Pasca, Maria Rosalia; Lherbet, Christian; Chassaing, Stefan
Nitric oxide-releasing compounds for the treatment of lung infections
2021-01-01 Chiarelli, Lr; Degiacomi, G; Egorova, A; Makarov, V; Pasca, Mr.
Pyridine-2-thiol 1-oxide derivatives and their use for treatment of mammalian infections caused by Mycobacterium or fungi
2022-01-01 Pasca, Mr; Degiacomi, G; Riabova, O; Makarov, V
Design of Anti-infectious Agents from Lawsone in a Three-Component Reaction with Aldehydes and Isocyanides
2022-01-01 Koumpoura, Christina L.; Nguyen, Michel; Bijani, Christian; Vendier, Laure; Salina, Elena G.; Buroni, Silvia; Degiacomi, Giulia; Cojean, Sandrine; Loiseau, Philippe M.; Benoit-Vical, Françoise; García-Sosa, Alfonso T.; Anne Robert, Null; Baltas, Michel
The Veterinary Anti-Parasitic Selamectin Is a Novel Inhibitor of the Mycobacterium tuberculosis DprE1 Enzyme
2022-01-01 Ezquerra-Aznarez, J. M.; Degiacomi, G.; Gasparovic, H.; Stelitano, G.; Sammartino, J. C.; Kordulakova, J.; Governa, P.; Manetti, F.; Pasca, M. R.; Chiarelli, L. R.; Ramon-Garcia, S.
New Drugs and Novel Cellular Targets against Tuberculosis
2022-01-01 Degiacomi, Giulia; Makarov, Vadim; Pasca, Maria Rosalia; Chiarelli, Laurent Roberto
A New Benzothiazolthiazolidine Derivative, 11726172, Is Active In Vitro, In Vivo, and against Nonreplicating Cells of Mycobacterium tuberculosis
2022-01-01 Salina, Elena G; Postiglione, Umberto; Chiarelli, Laurent R; Recchia, Deborah; Záhorszká, Monika; Lepioshkin, Alexander; Monakhova, Natalia; Pál, Adrian; Porta, Alessio; Zanoni, Giuseppe; Korduláková, Jana; Kazakova, Elena; Sassera, Davide; Pasca, Maria Rosalia; Makarov, Vadim; Degiacomi, Giulia
Functional investigation of the antitubercular drug target Decaprenylphosphoryl-β-D-ribofuranose-2-epimerase DprE1/DprE2 complex
2022-01-01 Sammartino, Josè Camilla; Morici, Martino; Stelitano, Giovanni; Degiacomi, Giulia; Riccardi, Giovanna; Chiarelli, Laurent Roberto
CanB, a Druggable Cellular Target in Mycobacterium tuberculosis
2023-01-01 Degiacomi, Giulia; Gianibbi, Beatrice; Recchia, Deborah; Stelitano, Giovanni; Truglio, Giuseppina Ivana; Marra, Paola; Stamilla, Alessandro; Makarov, Vadim; Chiarelli, Laurent Robert; Manetti, Fabrizio; Pasca, Maria Rosalia
Mycobacterium abscessus Infections in Cystic Fibrosis Individuals: A Review on Therapeutic Options
2023-01-01 Recchia, Deborah; Stelitano, Giovanni; Stamilla, Alessandro; Gutierrez, Damaris L; Degiacomi, Giulia; Chiarelli, Laurent R; Pasca, Maria Rosalia
Implementing best practices on data generation and reporting of Mycobacterium tuberculosis in vitro assays within the ERA4TB consortium
2023-01-01 van Wijk, Rob C; Lucía, Ainhoa; Sudhakar, Pavan Kumar; Sonnenkalb, Lindsay; Gaudin, Cyril; Hoffmann, Eik; Dremierre, Bérénice; Aguilar-Ayala, Diana Angélica; Molin, Michael Dal; Rybniker, Jan; de Giorgi, Stefano; Cioetto-Mazzabò, Laura; Segafreddo, Greta; Manganelli, Riccardo; Degiacomi, Giulia; Recchia, Deborah; Pasca, Maria Rosalia; Simonsson, Ulrika S H; Ramón-García, Santiago
Exploring the plasticity of the InhA substrate-binding site using new diaryl ether inhibitors
2023-01-01 Tamhaev, R; Grosjean, E; Ahamed, H; Chebaiki, M; Rodriguez, F; Recchia, D; Degiacomi, G; Pasca, Mr; Maveyraud, L; Mourey, L; Lherbet, C
Distinct Effects of Moxifloxacin and Bedaquiline on Growing and 'Non-Culturable' Mycobacterium abscessus
2023-01-01 Mulyukin, Andrey L; Recchia, Deborah; Kostrikina, Nadezhda A; Artyukhina, Maria V; Martini, Billy A; Stamilla, Alessandro; Degiacomi, Giulia; Salina, Elena G
Expanding the knowledge around antitubercular 5-(2-aminothiazol-4-yl)isoxazole-3-carboxamides: Hit-to-lead optimization and release of a novel antitubercular chemotype via scaffold derivatization
2023-01-01 Girardini, Miriam; Ferlenghi, Francesca; Annunziato, Giannamaria; Degiacomi, Giulia; Papotti, Bianca; Marchi, Cinzia; Rasheed, Sari S; Contini, Anna; Pasca, Maria Rosalia; Vacondio, Federica; Evans, Joanna C; Dick, Thomas; Müller, Rolf; Costantino, Gabriele; Pieroni, Marco; Sammartino, José Camilla
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Promiscuous Targets for Antitubercular Drug Discovery: The Paradigm of DprE1 and MmpL3 | 1-gen-2020 | Degiacomi, Giulia; Belardinelli, Juan Manuel; Pasca, Maria Rosalia; De Rossi, Edda; Riccardi, Giovanna; Chiarelli, Laurent R | |
| First triclosan-based macrocyclic inhibitors of InhA enzyme | 1-gen-2020 | Rodriguez, F; Saffon, N; Sammartino, Jc; Degiacomi, G; Pasca, Mr; Lherbet, C. | |
| Rv0579 Is Involved in the Resistance to the TP053 Antitubercular Prodrug | 1-gen-2020 | Mori, G; Silvia Orena, B; Chiarelli, Lr; Degiacomi, G; Riabova, O; Sammartino, Jc; Makarov, V; Riccardi, G; Pasca, M | |
| Design and Synthesis of Pyrano[3,2-b]indolones Showing Antimycobacterial Activity | 1-gen-2021 | Monakhova, N.; Kordulakova, J.; Vocat, A.; Egorova, A.; Lepioshkin, A.; Salina, E. G.; Nosek, J.; Repkova, E.; Zemanova, J.; Jurdakova, H.; Gorova, R.; Roh, J.; Degiacomi, G.; Sammartino, J. C.; Pasca, M. R.; Cole, S. T.; Mikusova, K.; Makarov, V. | |
| Age-related changes in PD-1 expression coincide with increased cytotoxic potential in Vδ2 T cells during infancy | 1-gen-2021 | Hsu, H.; Boudova, S.; Mvula, G.; Divala, T. H.; Rach, D.; Mungwira, R. G.; Boldrin, F.; Degiacomi, G.; Manganelli, R.; Laufer, M. K.; Cairo, C. | |
| The antimalarial mefloquine shows activity against mycobacterium abscessus, inhibiting mycolic acid metabolism | 1-gen-2021 | Degiacomi, G.; Chiarelli, L. R.; Recchia, D.; Petricci, E.; Gianibbi, B.; Fiscarelli, E. V.; Fattorini, L.; Manetti, F.; Pasca, M. R. | |
| A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in Mycobacterium tuberculosis | 1-gen-2021 | Farjallah, Asma; Chiarelli, Laurent R; Forbak, Martin; Degiacomi, Giulia; Danel, Mathieu; Goncalves, Fernanda; Carayon, Chantal; Seguin, Cendrine; Fumagalli, Marco; Záhorszká, Monika; Vega, Elodie; Abid, Souhir; Grzegorzewicz, Anna; Jackson, Mary; Peixoto, Antonio; Korduláková, Jana; Pasca, Maria Rosalia; Lherbet, Christian; Chassaing, Stefan | |
| Nitric oxide-releasing compounds for the treatment of lung infections | 1-gen-2021 | Chiarelli, Lr; Degiacomi, G; Egorova, A; Makarov, V; Pasca, Mr. | |
| Pyridine-2-thiol 1-oxide derivatives and their use for treatment of mammalian infections caused by Mycobacterium or fungi | 1-gen-2022 | Pasca, Mr; Degiacomi, G; Riabova, O; Makarov, V | |
| Design of Anti-infectious Agents from Lawsone in a Three-Component Reaction with Aldehydes and Isocyanides | 1-gen-2022 | Koumpoura, Christina L.; Nguyen, Michel; Bijani, Christian; Vendier, Laure; Salina, Elena G.; Buroni, Silvia; Degiacomi, Giulia; Cojean, Sandrine; Loiseau, Philippe M.; Benoit-Vical, Françoise; García-Sosa, Alfonso T.; Anne Robert, Null; Baltas, Michel | |
| The Veterinary Anti-Parasitic Selamectin Is a Novel Inhibitor of the Mycobacterium tuberculosis DprE1 Enzyme | 1-gen-2022 | Ezquerra-Aznarez, J. M.; Degiacomi, G.; Gasparovic, H.; Stelitano, G.; Sammartino, J. C.; Kordulakova, J.; Governa, P.; Manetti, F.; Pasca, M. R.; Chiarelli, L. R.; Ramon-Garcia, S. | |
| New Drugs and Novel Cellular Targets against Tuberculosis | 1-gen-2022 | Degiacomi, Giulia; Makarov, Vadim; Pasca, Maria Rosalia; Chiarelli, Laurent Roberto | |
| A New Benzothiazolthiazolidine Derivative, 11726172, Is Active In Vitro, In Vivo, and against Nonreplicating Cells of Mycobacterium tuberculosis | 1-gen-2022 | Salina, Elena G; Postiglione, Umberto; Chiarelli, Laurent R; Recchia, Deborah; Záhorszká, Monika; Lepioshkin, Alexander; Monakhova, Natalia; Pál, Adrian; Porta, Alessio; Zanoni, Giuseppe; Korduláková, Jana; Kazakova, Elena; Sassera, Davide; Pasca, Maria Rosalia; Makarov, Vadim; Degiacomi, Giulia | |
| Functional investigation of the antitubercular drug target Decaprenylphosphoryl-β-D-ribofuranose-2-epimerase DprE1/DprE2 complex | 1-gen-2022 | Sammartino, Josè Camilla; Morici, Martino; Stelitano, Giovanni; Degiacomi, Giulia; Riccardi, Giovanna; Chiarelli, Laurent Roberto | |
| CanB, a Druggable Cellular Target in Mycobacterium tuberculosis | 1-gen-2023 | Degiacomi, Giulia; Gianibbi, Beatrice; Recchia, Deborah; Stelitano, Giovanni; Truglio, Giuseppina Ivana; Marra, Paola; Stamilla, Alessandro; Makarov, Vadim; Chiarelli, Laurent Robert; Manetti, Fabrizio; Pasca, Maria Rosalia | |
| Mycobacterium abscessus Infections in Cystic Fibrosis Individuals: A Review on Therapeutic Options | 1-gen-2023 | Recchia, Deborah; Stelitano, Giovanni; Stamilla, Alessandro; Gutierrez, Damaris L; Degiacomi, Giulia; Chiarelli, Laurent R; Pasca, Maria Rosalia | |
| Implementing best practices on data generation and reporting of Mycobacterium tuberculosis in vitro assays within the ERA4TB consortium | 1-gen-2023 | van Wijk, Rob C; Lucía, Ainhoa; Sudhakar, Pavan Kumar; Sonnenkalb, Lindsay; Gaudin, Cyril; Hoffmann, Eik; Dremierre, Bérénice; Aguilar-Ayala, Diana Angélica; Molin, Michael Dal; Rybniker, Jan; de Giorgi, Stefano; Cioetto-Mazzabò, Laura; Segafreddo, Greta; Manganelli, Riccardo; Degiacomi, Giulia; Recchia, Deborah; Pasca, Maria Rosalia; Simonsson, Ulrika S H; Ramón-García, Santiago | |
| Exploring the plasticity of the InhA substrate-binding site using new diaryl ether inhibitors | 1-gen-2023 | Tamhaev, R; Grosjean, E; Ahamed, H; Chebaiki, M; Rodriguez, F; Recchia, D; Degiacomi, G; Pasca, Mr; Maveyraud, L; Mourey, L; Lherbet, C | |
| Distinct Effects of Moxifloxacin and Bedaquiline on Growing and 'Non-Culturable' Mycobacterium abscessus | 1-gen-2023 | Mulyukin, Andrey L; Recchia, Deborah; Kostrikina, Nadezhda A; Artyukhina, Maria V; Martini, Billy A; Stamilla, Alessandro; Degiacomi, Giulia; Salina, Elena G | |
| Expanding the knowledge around antitubercular 5-(2-aminothiazol-4-yl)isoxazole-3-carboxamides: Hit-to-lead optimization and release of a novel antitubercular chemotype via scaffold derivatization | 1-gen-2023 | Girardini, Miriam; Ferlenghi, Francesca; Annunziato, Giannamaria; Degiacomi, Giulia; Papotti, Bianca; Marchi, Cinzia; Rasheed, Sari S; Contini, Anna; Pasca, Maria Rosalia; Vacondio, Federica; Evans, Joanna C; Dick, Thomas; Müller, Rolf; Costantino, Gabriele; Pieroni, Marco; Sammartino, José Camilla |
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