Sfoglia per Rivista
Population Pharmacokinetic Model of Ibrutinib, a BTK Inhibitor for the Treatment of B-cell malignancies
2013-01-01 Marostica, Eleonora; Juthamas, Sukbuntherng; David, Loury; Jan de, Jong; Xavier Woot de, Trixhe; An, Vermeulen; DE NICOLAO, Giuseppe; Danelle, James; Italo, Poggesi
Population state-space modelling of patient responses in antidepressant studies
2011-01-01 Marostica, Eleonora; Russu, Alberto; DE NICOLAO, Giuseppe; R., Gomeni
Predicting tumor volume doubling time and progression-free survival curves in cancer patients from patient-derived-xenograft (PDX) models: a translational model-based population approach
2023-01-01 Tosca, E. M.; Ronchi, D.; Cossali, M.; Zavetteri, M.; Rocchetti, M.; Magni, P.
Predictive assessments of pharmacokinetic alterations in subjects with renal disease
2015-01-01 Borella, Elisa; Poggesi, Italo; Magni, Paolo
Prospective Evaluation of a Model-Based approach to select Phase 1 Dosing Regimen for MEN1309/OBT076, a novel antibody drug conjugate (ADC) targeting Ly75 antigen for the treatment of CD205-positive metastatic solid tumours and Non-Hodgkin lymphoma
2019-01-01 Borella, E.; Mazzei, P.; Piana, C.; Tagliavini, A.; Magni, P.; Buontempo, S.; Tagliacozzi, D.; Fedi, V.; Capriati, A.; Pellacani, A.
Reduced food-intake and sarcopenia in animal models of cancer anorexia-cachexia syndrome: a Dynamic Energy Budget (DEB)-based modeling approach
2021-01-01 Tosca, E. M.; Montanaro, A.; Rocchetti, M.; Magni, P.
Second order Markov modelling of HAMD responses in depression trials
2012-01-01 Marostica, Eleonora; Russu, Alberto; S., Zamuner; R., Gomeni; DE NICOLAO, Giuseppe
Second-order indirect response modelling of complex biomarker dynamics
2013-01-01 A., Russu; Marostica, Eleonora; DE NICOLAO, Giuseppe; I., Poggesi
Steady-state equivalence of drug- and biomarker driven models in tumor growth experiments
2014-01-01 Sardu, MARIA LUISA; Poggesi, Italo; DE NICOLAO, Giuseppe
Translational model-based approach to assist the dose-range selection of an antibody-drug conjugate entering Phase I
2017-01-01 Mazzei, P.; Smania, Giovanni; Piana, C.; Magni, Paolo; Binaschi, M.; Bigioni, M.; Merlino, G.; Bugianesi, R.; Chirulli, V.; Simonelli, C.; Capriati, A.; Pellacani, A.
A tumor-in-host Dynamic Energy Budget (DEB)-based paradigm for preclinical to clinical translation: predictions of tumor-in-host growth dynamics
2021-01-01 Tosca, E. M.; Castellano, S.; Ronchi, D.; Rocchetti, M.; Magni, P.
A Two-Stages Global Sensitivity Analysis in presence of correlated inputs: Application on a Tumor-in-host-growth Inhibition model based on the Dynamic Energy Budget theory
2022-01-01 De Carlo, A.; Tosca, E. M.; Melillo, N.; Magni, P.
Variance based Global Sensitivity Analysis of a Physiological Absorption model for compounds in different BCS classes
2018-01-01 Melillo, N.; Aarons, L.; Magni, P.; Darwich, A. S.
Which data are necessary to build a WB-PBPK model that accurately predicts exposure in the lung? A case study using Ethambutol for tuberculosis treatment
2017-01-01 Carrara, Letizia; Magni, Paolo; Teutonico, D.; Della Pasqua, O.; Kloprogge, F.
Legenda icone
- file ad accesso aperto
- file disponibili sulla rete interna
- file disponibili agli utenti autorizzati
- file disponibili solo agli amministratori
- file sotto embargo
- nessun file disponibile