Sfoglia per Rivista
A model-based approach to extrapolate drug-drug interactions from rats to humans
2017-01-01 Piana, C.; Mazzei, P.; Smania, Giovanni; Magni, Paolo; Lecci, A.; Capriati, A.; Pellacani, A.
Model-based comparison of alternative study designs in paediatric trials
2015-01-01 Smania, Giovanni; Baiardi, P.; Cella, M.; Magni, Paolo
Modelling of protozoa dynamics and drug effects in a murine model of malaria infection
2012-01-01 Terranova, Nadia; M. B., Jimenez Diaz; I., Angulo Barturen; Magni, Paolo; O., Della Pasqua
Modelling the effect of Sunitinib given alone and in combination with CPT-11 on the tumor growth in xenografted mice
2015-01-01 Carrara, Letizia; Ribba, B.; Tod, M.; Wei, M.; You, B.; Freyer, G.; Magni, Paolo
Multiscale mechanistic models in Systems Pharmacology: development of a model describing Atorvastatin pharmacokinetics through integration of metabolic network in Physiologically Based Pharmacokinetic models
2017-01-01 Melillo, Nicola; Pasotti, Lorenzo; Magni, Paolo
Optimal design for informative protocols in xenograft tumor growth inhibition models
2015-01-01 Lestini, Giulia; Mentré, F.; Magni, Paolo
Optimal design of paediatric clinical trials: the Macitentan case study
2019-01-01 Bartolucci, R.; Magni, P.
Paediatric trial design optimization using prior knowledge in combination with modelling & simulations
2017-01-01 Borella, Elisa; Oosterholt, S.; Magni, Paolo; Della Pasqua, O.
A PBPK model for the study of Azathioprine pharmacokinetics in rats and prediction in humans
2018-01-01 Bartolucci, R.; Melillo, N.; Magni, P.
PCA-based modelling in antidepressant trials: a pre-mechanistic approach
2012-01-01 Marostica, Eleonora; Russu, Alberto; S., Zamuner; R., Gomeni; DE NICOLAO, Giuseppe
Pharmacokinetic Models for Drug and Metabolites Including First Pass Effects: A Priori and A Posteriori Identifiability Analysis
2019-01-01 Lavezzi, S. M.; Zhang, J.; Magni, P.; De Nicolao, G.; Iavarone, L.
A PK/PD model for tumor-in-host growth kinetics following administration of an antiangiogenic agent given alone or in combination regimens
2017-01-01 Tosca, ELENA MARIA; Rocchetti, M.; Magni, Paolo
PK/PD modeling of tumor growth inhibition after etoposide administration in vitro and to tumor-bearing rats
2015-01-01 Pigatto, M. C.; Roman, R. M.; Carrara, Letizia; Magni, Paolo; Dalla Costa, T.
PKPD modelling of MEN1611 anti-tumor effect in xenograft models to predict efficacy threshold concentrations in HER2-positive advanced or metastatic breast cancer patient population
2021-01-01 Tosca, E. M.; Borella, E.; Piana, C.; Fornari, C.; Bartolucci, R.; Mazzei, P.; Capriati, A.; Merlino, G.; Capano, S.; Laurent, D.; Pellacani, A.; Magni, P.
Population Pharmacokinetic Model of Ibrutinib, a BTK Inhibitor for the Treatment of B-cell malignancies
2013-01-01 Marostica, Eleonora; Juthamas, Sukbuntherng; David, Loury; Jan de, Jong; Xavier Woot de, Trixhe; An, Vermeulen; DE NICOLAO, Giuseppe; Danelle, James; Italo, Poggesi
Population state-space modelling of patient responses in antidepressant studies
2011-01-01 Marostica, Eleonora; Russu, Alberto; DE NICOLAO, Giuseppe; R., Gomeni
Predicting tumor volume doubling time and progression-free survival curves in cancer patients from patient-derived-xenograft (PDX) models: a translational model-based population approach
2023-01-01 Tosca, E. M.; Ronchi, D.; Cossali, M.; Zavetteri, M.; Rocchetti, M.; Magni, P.
Predictive assessments of pharmacokinetic alterations in subjects with renal disease
2015-01-01 Borella, Elisa; Poggesi, Italo; Magni, Paolo
Prospective Evaluation of a Model-Based approach to select Phase 1 Dosing Regimen for MEN1309/OBT076, a novel antibody drug conjugate (ADC) targeting Ly75 antigen for the treatment of CD205-positive metastatic solid tumours and Non-Hodgkin lymphoma
2019-01-01 Borella, E.; Mazzei, P.; Piana, C.; Tagliavini, A.; Magni, P.; Buontempo, S.; Tagliacozzi, D.; Fedi, V.; Capriati, A.; Pellacani, A.
Reduced food-intake and sarcopenia in animal models of cancer anorexia-cachexia syndrome: a Dynamic Energy Budget (DEB)-based modeling approach
2021-01-01 Tosca, E. M.; Montanaro, A.; Rocchetti, M.; Magni, P.
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