GHERARDI, ERMANNO
GHERARDI, ERMANNO
DIPARTIMENTO DI MEDICINA MOLECOLARE
A G2/M cell cycle block in transformed cells by contact with normal neighbors.
2003-01-01 Allard, D; Stoker, M; Gherardi, Ermanno
A Mechanistic Basis for Converting a Growth-Factor Receptor Agonist to an Antagonist.
2007-01-01 Tolbert, D; Daugherty, J; Gao, Cf; Xie, X; Miranti, C; Gherardi, Ermanno; VANDE WOUDE, G; Xu, Eh
A new crystal form of the NK1 splice variant of HGF/SF demonstrates extensive hinge movement and suggests that the NK1 dimer originates by domain swapping.
2002-01-01 Watanabe, K; Chirgadze, Dy; Lietha, D; DE JONGE, Hugo; Blundell, Tl; Gherardi, Ermanno
A novel HGF/SF receptor (MET) agonist transiently delays the disease progression in an amyotrophic lateral sclerosis mouse model by promoting neuronal survival and dampening the immune dysregulation
2020-01-01 Vallarola, A.; Tortarolo, M.; De Gioia, R.; Iamele, L.; de Jonge, H.; de Nola, G.; Bovio, E.; Pasetto, L.; Bonetto, V.; Freschi, M.; Bendotti, C.; Gherardi, E.
A Novel Multipurpose Monoclonal Antibody for Evaluating Human c-Met Expression in Preclinical and Clinical Settings
2009-01-01 Beatrice S., Knudsen; Ping, Zhao; James, Resau; Sandra, Cottingham; Gherardi, Ermanno; Eric, Xu; Bree, Berghuis; Jennifer, Daugherty; Tessa, Grabinski; Jose, Toro; Troy, Giambernardi; R., Scot Skinner; Milton, Gross; Eric, Hudson; Eric, Kort; Ernst, Lengyel; Aviva, Ventura; Richard A., West; Qian, Xie; Rick, Hay; George Vande, Woude; Brian, Cao
A role of HGF/SF in neural induction and its expression in Hensen's node during gastrulation.
1995-01-01 Streit, A; Stern, Cd; Théry, C; Ireland, Gw; Aparicio, S; Sharpe, M; Gherardi, Ermanno
Affinity Maturation of Antibodies in the 2-Phenyl-5-Oxazolone System
2010-01-01 Scotti, Claudia; Pasquetto, MARIA VALENTINA; Gherardi, Ermanno
An approach to random mutagenesis of DNA using mixtures of triphosphate derivatives of nucleoside analogues.
1996-01-01 Zaccolo, ; Williams, Dm; Brown, Dm; Gherardi, Ermanno
Aromatic amino acids at the surface of InlB are essential for host cell invasion by Listeria monocytogenes.
2003-01-01 Gherardi, Ermanno; Machner, Mp; Frese, S; Schubert, Wd; Orian Rousseau, V; Wehland, J; Niemann, Hh; Heinz, D. w.
Characterisation of the SF/HGF gene promoter.
1995-01-01 PLASCHKE SCHLUTTER, A; Lowrick, O; Behrens, J; Gherardi, Ermanno; Birchmeier, W.
Characterization and structural determination of a new anti-MET function-blocking antibody with binding epitope distinct from the ligand binding domain
2017-01-01 Dicara, Danielle M.; Chirgadze, Dimitri Y.; Pope, Anthony R.; Karatt-Vellatt, Aneesh; Winter, Anja; Slavny, Peter; Van Den Heuvel, Joop; Parthiban, Kothai; Holland, Jane; Packman, Len C.; Mavria, Georgia; Hoffmann, Jens; Birchmeier, Walter; Gherardi, Ermanno; Mccafferty, John
Co-expression of the HGF/SF and c-met genes during early mouse embryongenesis precedes reciprocal expression in adjacent tissues during organogenesis
1996-01-01 Andermarcher, E; Surani, Ma; Gherardi, Ermanno
Computer-assisted mass spectrometric analysis of naturally occurring and artificially introduced cross-links in proteins and protein complexes.
2006-01-01 DE KONING, Lj; Kasper, Pt; Back, Jw; Nessen, Ma; Vanrobaeys, F; VAN BEEUMEN, J; Gherardi, Ermanno; DE KOSTER, Cg; DE JONG, L.
Coupling growth-factor engineering with nanotechnology for therapeutic angiogenesis
2010-01-01 R., Sinha Roy; S., Soni; R., Harfouche; P. R., Vasudevan; O., Holmes; DE JONGE, Hugo; A., Rowe; A., Paraskar; D. M., Hentschel; D., Chirgadze; T. L., Blundell; Gherardi, Ermanno; R. A., Mashelkar; S., Sengupta
Crystal structure of an engineered YopM-InlB hybrid protein
2014-01-01 Dennis, Breitsprecher; Gherardi, Ermanno; Willem M., Bleymüller; Hartmut H., Niemann
Crystal structure of the beta-chain of human hepatocyte growth factor-like/macrophage stimulating protein.
2005-01-01 Carafoli, F; Chirgadze, Dy; Blundell, Tl; Gherardi, Ermanno
Crystal structure of the NK1 fragment of HGF/SF suggests a novel mode for growth factor dimerization and receptor binding.
1999-01-01 Chirgadze, D; Hepple, Jh; Zhou, H; Byrd, Ra; Blundell, T; Gherardi, Ermanno
Crystal structures of NK1-heparin complexes reveal the basis for NK1 activity and enable engineering of potent agonists of the MET receptor.
2001-01-01 Lietha, D; Chirgadze, Dy; Mulloy, B; Blundell, Tl; Gherardi, Ermanno
Cyclooxygenase-2-selective nonsteroidal anti-inflammatory drugs inhibit
2004-01-01 Gherardi, Ermanno; Sengupta, S; Sellers, La; Cindrova, T; Skepper, J; Sasisekharan, R.
Developing antagonists for the Met-HGF/SF protein-protein interaction using a fragment-based approach
2016-01-01 Winter, Anja; Sigurdardottir, Anna G.; Dicara, Danielle; Valenti, Giovanni; Blundell, Tom L; Gherardi, Ermanno
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A G2/M cell cycle block in transformed cells by contact with normal neighbors. | 1-gen-2003 | Allard, D; Stoker, M; Gherardi, Ermanno | |
| A Mechanistic Basis for Converting a Growth-Factor Receptor Agonist to an Antagonist. | 1-gen-2007 | Tolbert, D; Daugherty, J; Gao, Cf; Xie, X; Miranti, C; Gherardi, Ermanno; VANDE WOUDE, G; Xu, Eh | |
| A new crystal form of the NK1 splice variant of HGF/SF demonstrates extensive hinge movement and suggests that the NK1 dimer originates by domain swapping. | 1-gen-2002 | Watanabe, K; Chirgadze, Dy; Lietha, D; DE JONGE, Hugo; Blundell, Tl; Gherardi, Ermanno | |
| A novel HGF/SF receptor (MET) agonist transiently delays the disease progression in an amyotrophic lateral sclerosis mouse model by promoting neuronal survival and dampening the immune dysregulation | 1-gen-2020 | Vallarola, A.; Tortarolo, M.; De Gioia, R.; Iamele, L.; de Jonge, H.; de Nola, G.; Bovio, E.; Pasetto, L.; Bonetto, V.; Freschi, M.; Bendotti, C.; Gherardi, E. | |
| A Novel Multipurpose Monoclonal Antibody for Evaluating Human c-Met Expression in Preclinical and Clinical Settings | 1-gen-2009 | Beatrice S., Knudsen; Ping, Zhao; James, Resau; Sandra, Cottingham; Gherardi, Ermanno; Eric, Xu; Bree, Berghuis; Jennifer, Daugherty; Tessa, Grabinski; Jose, Toro; Troy, Giambernardi; R., Scot Skinner; Milton, Gross; Eric, Hudson; Eric, Kort; Ernst, Lengyel; Aviva, Ventura; Richard A., West; Qian, Xie; Rick, Hay; George Vande, Woude; Brian, Cao | |
| A role of HGF/SF in neural induction and its expression in Hensen's node during gastrulation. | 1-gen-1995 | Streit, A; Stern, Cd; Théry, C; Ireland, Gw; Aparicio, S; Sharpe, M; Gherardi, Ermanno | |
| Affinity Maturation of Antibodies in the 2-Phenyl-5-Oxazolone System | 1-gen-2010 | Scotti, Claudia; Pasquetto, MARIA VALENTINA; Gherardi, Ermanno | |
| An approach to random mutagenesis of DNA using mixtures of triphosphate derivatives of nucleoside analogues. | 1-gen-1996 | Zaccolo, ; Williams, Dm; Brown, Dm; Gherardi, Ermanno | |
| Aromatic amino acids at the surface of InlB are essential for host cell invasion by Listeria monocytogenes. | 1-gen-2003 | Gherardi, Ermanno; Machner, Mp; Frese, S; Schubert, Wd; Orian Rousseau, V; Wehland, J; Niemann, Hh; Heinz, D. w. | |
| Characterisation of the SF/HGF gene promoter. | 1-gen-1995 | PLASCHKE SCHLUTTER, A; Lowrick, O; Behrens, J; Gherardi, Ermanno; Birchmeier, W. | |
| Characterization and structural determination of a new anti-MET function-blocking antibody with binding epitope distinct from the ligand binding domain | 1-gen-2017 | Dicara, Danielle M.; Chirgadze, Dimitri Y.; Pope, Anthony R.; Karatt-Vellatt, Aneesh; Winter, Anja; Slavny, Peter; Van Den Heuvel, Joop; Parthiban, Kothai; Holland, Jane; Packman, Len C.; Mavria, Georgia; Hoffmann, Jens; Birchmeier, Walter; Gherardi, Ermanno; Mccafferty, John | |
| Co-expression of the HGF/SF and c-met genes during early mouse embryongenesis precedes reciprocal expression in adjacent tissues during organogenesis | 1-gen-1996 | Andermarcher, E; Surani, Ma; Gherardi, Ermanno | |
| Computer-assisted mass spectrometric analysis of naturally occurring and artificially introduced cross-links in proteins and protein complexes. | 1-gen-2006 | DE KONING, Lj; Kasper, Pt; Back, Jw; Nessen, Ma; Vanrobaeys, F; VAN BEEUMEN, J; Gherardi, Ermanno; DE KOSTER, Cg; DE JONG, L. | |
| Coupling growth-factor engineering with nanotechnology for therapeutic angiogenesis | 1-gen-2010 | R., Sinha Roy; S., Soni; R., Harfouche; P. R., Vasudevan; O., Holmes; DE JONGE, Hugo; A., Rowe; A., Paraskar; D. M., Hentschel; D., Chirgadze; T. L., Blundell; Gherardi, Ermanno; R. A., Mashelkar; S., Sengupta | |
| Crystal structure of an engineered YopM-InlB hybrid protein | 1-gen-2014 | Dennis, Breitsprecher; Gherardi, Ermanno; Willem M., Bleymüller; Hartmut H., Niemann | |
| Crystal structure of the beta-chain of human hepatocyte growth factor-like/macrophage stimulating protein. | 1-gen-2005 | Carafoli, F; Chirgadze, Dy; Blundell, Tl; Gherardi, Ermanno | |
| Crystal structure of the NK1 fragment of HGF/SF suggests a novel mode for growth factor dimerization and receptor binding. | 1-gen-1999 | Chirgadze, D; Hepple, Jh; Zhou, H; Byrd, Ra; Blundell, T; Gherardi, Ermanno | |
| Crystal structures of NK1-heparin complexes reveal the basis for NK1 activity and enable engineering of potent agonists of the MET receptor. | 1-gen-2001 | Lietha, D; Chirgadze, Dy; Mulloy, B; Blundell, Tl; Gherardi, Ermanno | |
| Cyclooxygenase-2-selective nonsteroidal anti-inflammatory drugs inhibit | 1-gen-2004 | Gherardi, Ermanno; Sengupta, S; Sellers, La; Cindrova, T; Skepper, J; Sasisekharan, R. | |
| Developing antagonists for the Met-HGF/SF protein-protein interaction using a fragment-based approach | 1-gen-2016 | Winter, Anja; Sigurdardottir, Anna G.; Dicara, Danielle; Valenti, Giovanni; Blundell, Tom L; Gherardi, Ermanno |