PASCA, MARIA ROSALIA
PASCA, MARIA ROSALIA
DIPARTIMENTO DI BIOLOGIA E BIOTECNOLOGIE "LAZZARO SPALLANZANI"
2-Aminooxazole as a Novel Privileged Scaffold in Antitubercular Medicinal Chemistry.
2020-01-01 Azzali, E; Girardini, M; Annunziato, G; Pavone, M; Vacondio, F; Mori, G; Pasca, Mr; Costantino, G; Pieroni, M.
2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1.
2015-01-01 Neres, J; Hartkoorn, Rc; Chiarelli, Laurent; Gadupudi, R; Pasca, MARIA ROSALIA; Mori, Giorgia; Venturelli, A; Savina, S; Makarov, V; Kolly, Gs; Molteni, E; Binda, Claudia; Dhar, N; Ferrari, S; Brodin, P; Delorme, V; Landry, V; de Jesus Lopes Ribeiro, Al; Farina, D; Saxena, P; Pojer, F; Carta, A; Luciani, R; Porta, Alessio; Zanoni, G; DE ROSSI, Edda; Costi, Mp; Riccardi, Giovanna; Cole, S. T.
4-Aminoquinolone Piperidine Amides: Non-Covalent Inhibitors of DprE1 with Long Residence Time and Potent Antimycobacterial Activity.
2014-01-01 Naik, M; Humnabadkar, V; Tantry, Sj; Panda, M; Narayan, A; Guptha, S; Panduga, V; Manjrekar, P; Jena, Lk; Koushik, K; Shanbhag, G; Jatheendranath, S; M. R., M.; Gorai, G; Bathula, C; Rudrapatna, S; Achar, V; Sharma, S; Ambady, A; Hegde, N; Mahadevaswamy, J; Kaur, P; Sambandamurthy, Vk; Awasthy, D; Narayanan, C; Ravishankar, S; Madhavapeddi, P; Reddy, J; Kr, P; Saralaya, R; Chatterji, M; Whiteaker, J; Mclaughlin, R; Chiarelli, Laurent; Riccardi, Giovanna; Pasca, MARIA ROSALIA; Binda, Claudia; Neres, Jp; Dhar, N; Signorino Gelo, F; Mckinney, J; Ramachandran, V; Shandil, R; Tommasi, R; Iyer, Ps; Narayanan, S; Hosagrahara, V; Kavanagh, S; Dinesh, N; Ghorpade, S. R.
A census of RND superfamily proteins in the Burkholderia genus.
2013-01-01 Perrin, E; Fondi, M; Papaleo, Mc; Maida, I; Emiliani, G; Buroni, Silvia; Pasca, MARIA ROSALIA; Riccardi, Giovanna; Fani, R.
A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in Mycobacterium tuberculosis
2021-01-01 Farjallah, Asma; Chiarelli, Laurent R; Forbak, Martin; Degiacomi, Giulia; Danel, Mathieu; Goncalves, Fernanda; Carayon, Chantal; Seguin, Cendrine; Fumagalli, Marco; Záhorszká, Monika; Vega, Elodie; Abid, Souhir; Grzegorzewicz, Anna; Jackson, Mary; Peixoto, Antonio; Korduláková, Jana; Pasca, Maria Rosalia; Lherbet, Christian; Chassaing, Stefan
A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK
2018-01-01 Chiarelli, L; Mori, G; Orena, Bs; Esposito, M; Lane, T; de Lopes Jesus Ribeiro, Al; Degiacomi, G; Zemanova, J; Szadocka, S; Huszar, S; Palcekova, Z; Manfredi, M; Gosetti, F; Lelievre, J; Ballell, L; Kazakova, E; Makarov, V; Marengo, E; Mikusova, K; Cole, St; Riccardi, G; Ekins, S; Pasca, Mr
A New Benzothiazolthiazolidine Derivative, 11726172, Is Active In Vitro, In Vivo, and against Nonreplicating Cells of Mycobacterium tuberculosis
2022-01-01 Salina, Elena G; Postiglione, Umberto; Chiarelli, Laurent R; Recchia, Deborah; Záhorszká, Monika; Lepioshkin, Alexander; Monakhova, Natalia; Pál, Adrian; Porta, Alessio; Zanoni, Giuseppe; Korduláková, Jana; Kazakova, Elena; Sassera, Davide; Pasca, Maria Rosalia; Makarov, Vadim; Degiacomi, Giulia
A pharmaceutical combination for the treatment of lung infections in subjects with cystic fibrosis
2024-01-01 Pasca, Mr; Ramon-Garcia, S; Munoz-Munoz, L; Makarov, V.
A phenotypic based target screening approach delivers new antitubercular CTP synthetase inhibitors
2017-01-01 Esposito, Marta; Szadocka, Sára; Degiacomi, Giulia; Orena, BEATRICE SILVIA; Mori, Giorgia; Piano, Valentina; Boldrin, Francesca; Zemanova, Julia; Huszár, Stanislav; Barros, David; Ekins, Sean; Lelièvre, Joël; Manganelli, Riccardo; Mattevi, Andrea; Pasca, MARIA ROSALIA; Riccardi, Giovanna; Ballell, Lluis; Mikušová, Katarína; Chiarelli, Laurent
AN EFFECTIVE NEW DRUG TARGET FOR THE TREATMENT OF TUBERCULOSIS
2008-01-01 Riccardi, Giovanna; Manina, Giulia; Pasca, MARIA ROSALIA
Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis
2011-01-01 De Jesus Lopes Ribeiro, Al; Degiacomi, Giulia; Ewann, F; Buroni, Silvia; Incandela, Ml; Chiarelli, Laurent; Mori, G; Kim, J; Contreras Dominguez, M; Park, Ys; Han, Sj; Brodin, P; Valentini, Giovanna; Rizzi, M; Riccardi, Giovanna; Pasca, MARIA ROSALIA
Analyzing the role of RND efflux transporters in Burkholderia cenocepacia: a proteomic analysis.
2011-01-01 Papaleo, M. C.; Gamberi, T.; Fondi, M.; Maida, I.; Perrin, E.; Emiliani, G.; Buroni, Silvia; Bazzini, S.; Udine, Claudia; Pasca, MARIA ROSALIA; DE ROSSI, Edda; Modesti, A.; Longo, F.; Emiliani, G.; Fondi, M.; Perrin, E.; Decorosi, F.; Viti, C.; Giovannetti, L.; Leoni, L.; Riccardi, Giovanna; Fani, R.
Assessment of three Resistance-Nodulation-Cell Division drug efflux transporters of Burkholderia cenocepacia in intrinsic antibiotic resistance
2009-01-01 Buroni, Silvia; Pasca, MARIA ROSALIA; Flannagan, R. S.; Bazzini, S.; Milano, Anna; Bertani, I.; Venturi, V.; Valvano, M. A.; Riccardi, Giovanna
Azole drug resistance in Mycobacterium tuberculosis
2007-01-01 Provvedi, R.; Pasca, MARIA ROSALIA; Milano, Anna; Lucarelli, ANNA PAOLA; Manina, Giulia; Manganelli, R.; Riccardi, Giovanna
Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5-MmpL5 efflux system
2009-01-01 Milano, Anna; Pasca, MARIA ROSALIA; Provvedi, R.; Lucarelli, ANNA PAOLA; Manina, Giulia; DE JESUS LOPES RIBEIRO, A. L.; Manganelli, R.; Riccardi, Giovanna
Benzothiazinones Are Suicide Inhibitors of Mycobacterial Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase DprE1.
2012-01-01 Trefzer, C; Skovierová, H; Buroni, Silvia; Bobovská, A; Nenci, Simone; Molteni, Elisabetta; Pojer, F; Pasca, MARIA ROSALIA; Makarov, V; Cole, St; Riccardi, Giovanna; Mikušová, K; Johnsson, K.
Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis
2009-01-01 Makarov, V; Manina, Giulia; Mikusova, K; Möllmann, U; Ryabova, O; SAINT JOANIS, B; Dhar, N; Pasca, MARIA ROSALIA; Buroni, Silvia; Lucarelli, ANNA PAOLA; Milano, Anna; DE ROSSI, Edda; Belanova, M; Bobovska, A; Dianiskova, P; Kordulakova, J; Sala, C; Fullam, E; Schneider, P; Mckinney, Jd; Brodin, P; Christophe, T; Waddell, S; Butcher, P; Albrethsen, J; Rosenkrands, I; Brosch, R; Nandi, V; Bharath, S; Gaonkar, S; Shandil, Rk; Balasubramanian, V; Balganesh, T; Tyagi, S; Grosset, J; Riccardi, Giovanna; Cole, S. T.
Biological and structural characterization of theMycobacterium smegmatis nitroreductase NfnB, and its rolein benzothiazinone resistance
2010-01-01 Manina, Giulia; Bellinzoni, M; Pasca, MARIA ROSALIA; Neres, J; Milano, Anna; DE JESUS LOPES RIBEIRO, Al; Buroni, Silvia; Škovierová, H; Dianišková, P; Mikušová, K; Marák, J; Makarov, V; Giganti, D; Haouz, A; Lucarelli, ANNA PAOLA; Degiacomi, Giulia; Piazza, Aurora; Chiarelli, Laurent; DE ROSSI, Edda; Salina, E; Cole, St; Alzari, Pm; Riccardi, Giovanna
Bombas de eflujo como trasportadores de membrana implicados en resistencia a antibióticos en micobacterias
2005-01-01 Ramon Garcia, Santiago; Mick, Virginie; Buroni, Silvia; Arcesi, Fabio; Guglierame, Paola; Pasca, MARIA ROSALIA; Martin, Carlos; DE ROSSI, Edda; Ainsa, Jose
CanB, a Druggable Cellular Target in Mycobacterium tuberculosis
2023-01-01 Degiacomi, Giulia; Gianibbi, Beatrice; Recchia, Deborah; Stelitano, Giovanni; Truglio, Giuseppina Ivana; Marra, Paola; Stamilla, Alessandro; Makarov, Vadim; Chiarelli, Laurent Robert; Manetti, Fabrizio; Pasca, Maria Rosalia
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 2-Aminooxazole as a Novel Privileged Scaffold in Antitubercular Medicinal Chemistry. | 1-gen-2020 | Azzali, E; Girardini, M; Annunziato, G; Pavone, M; Vacondio, F; Mori, G; Pasca, Mr; Costantino, G; Pieroni, M. | |
| 2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1. | 1-gen-2015 | Neres, J; Hartkoorn, Rc; Chiarelli, Laurent; Gadupudi, R; Pasca, MARIA ROSALIA; Mori, Giorgia; Venturelli, A; Savina, S; Makarov, V; Kolly, Gs; Molteni, E; Binda, Claudia; Dhar, N; Ferrari, S; Brodin, P; Delorme, V; Landry, V; de Jesus Lopes Ribeiro, Al; Farina, D; Saxena, P; Pojer, F; Carta, A; Luciani, R; Porta, Alessio; Zanoni, G; DE ROSSI, Edda; Costi, Mp; Riccardi, Giovanna; Cole, S. T. | |
| 4-Aminoquinolone Piperidine Amides: Non-Covalent Inhibitors of DprE1 with Long Residence Time and Potent Antimycobacterial Activity. | 1-gen-2014 | Naik, M; Humnabadkar, V; Tantry, Sj; Panda, M; Narayan, A; Guptha, S; Panduga, V; Manjrekar, P; Jena, Lk; Koushik, K; Shanbhag, G; Jatheendranath, S; M. R., M.; Gorai, G; Bathula, C; Rudrapatna, S; Achar, V; Sharma, S; Ambady, A; Hegde, N; Mahadevaswamy, J; Kaur, P; Sambandamurthy, Vk; Awasthy, D; Narayanan, C; Ravishankar, S; Madhavapeddi, P; Reddy, J; Kr, P; Saralaya, R; Chatterji, M; Whiteaker, J; Mclaughlin, R; Chiarelli, Laurent; Riccardi, Giovanna; Pasca, MARIA ROSALIA; Binda, Claudia; Neres, Jp; Dhar, N; Signorino Gelo, F; Mckinney, J; Ramachandran, V; Shandil, R; Tommasi, R; Iyer, Ps; Narayanan, S; Hosagrahara, V; Kavanagh, S; Dinesh, N; Ghorpade, S. R. | |
| A census of RND superfamily proteins in the Burkholderia genus. | 1-gen-2013 | Perrin, E; Fondi, M; Papaleo, Mc; Maida, I; Emiliani, G; Buroni, Silvia; Pasca, MARIA ROSALIA; Riccardi, Giovanna; Fani, R. | |
| A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in Mycobacterium tuberculosis | 1-gen-2021 | Farjallah, Asma; Chiarelli, Laurent R; Forbak, Martin; Degiacomi, Giulia; Danel, Mathieu; Goncalves, Fernanda; Carayon, Chantal; Seguin, Cendrine; Fumagalli, Marco; Záhorszká, Monika; Vega, Elodie; Abid, Souhir; Grzegorzewicz, Anna; Jackson, Mary; Peixoto, Antonio; Korduláková, Jana; Pasca, Maria Rosalia; Lherbet, Christian; Chassaing, Stefan | |
| A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK | 1-gen-2018 | Chiarelli, L; Mori, G; Orena, Bs; Esposito, M; Lane, T; de Lopes Jesus Ribeiro, Al; Degiacomi, G; Zemanova, J; Szadocka, S; Huszar, S; Palcekova, Z; Manfredi, M; Gosetti, F; Lelievre, J; Ballell, L; Kazakova, E; Makarov, V; Marengo, E; Mikusova, K; Cole, St; Riccardi, G; Ekins, S; Pasca, Mr | |
| A New Benzothiazolthiazolidine Derivative, 11726172, Is Active In Vitro, In Vivo, and against Nonreplicating Cells of Mycobacterium tuberculosis | 1-gen-2022 | Salina, Elena G; Postiglione, Umberto; Chiarelli, Laurent R; Recchia, Deborah; Záhorszká, Monika; Lepioshkin, Alexander; Monakhova, Natalia; Pál, Adrian; Porta, Alessio; Zanoni, Giuseppe; Korduláková, Jana; Kazakova, Elena; Sassera, Davide; Pasca, Maria Rosalia; Makarov, Vadim; Degiacomi, Giulia | |
| A pharmaceutical combination for the treatment of lung infections in subjects with cystic fibrosis | 1-gen-2024 | Pasca, Mr; Ramon-Garcia, S; Munoz-Munoz, L; Makarov, V. | |
| A phenotypic based target screening approach delivers new antitubercular CTP synthetase inhibitors | 1-gen-2017 | Esposito, Marta; Szadocka, Sára; Degiacomi, Giulia; Orena, BEATRICE SILVIA; Mori, Giorgia; Piano, Valentina; Boldrin, Francesca; Zemanova, Julia; Huszár, Stanislav; Barros, David; Ekins, Sean; Lelièvre, Joël; Manganelli, Riccardo; Mattevi, Andrea; Pasca, MARIA ROSALIA; Riccardi, Giovanna; Ballell, Lluis; Mikušová, Katarína; Chiarelli, Laurent | |
| AN EFFECTIVE NEW DRUG TARGET FOR THE TREATMENT OF TUBERCULOSIS | 1-gen-2008 | Riccardi, Giovanna; Manina, Giulia; Pasca, MARIA ROSALIA | |
| Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis | 1-gen-2011 | De Jesus Lopes Ribeiro, Al; Degiacomi, Giulia; Ewann, F; Buroni, Silvia; Incandela, Ml; Chiarelli, Laurent; Mori, G; Kim, J; Contreras Dominguez, M; Park, Ys; Han, Sj; Brodin, P; Valentini, Giovanna; Rizzi, M; Riccardi, Giovanna; Pasca, MARIA ROSALIA | |
| Analyzing the role of RND efflux transporters in Burkholderia cenocepacia: a proteomic analysis. | 1-gen-2011 | Papaleo, M. C.; Gamberi, T.; Fondi, M.; Maida, I.; Perrin, E.; Emiliani, G.; Buroni, Silvia; Bazzini, S.; Udine, Claudia; Pasca, MARIA ROSALIA; DE ROSSI, Edda; Modesti, A.; Longo, F.; Emiliani, G.; Fondi, M.; Perrin, E.; Decorosi, F.; Viti, C.; Giovannetti, L.; Leoni, L.; Riccardi, Giovanna; Fani, R. | |
| Assessment of three Resistance-Nodulation-Cell Division drug efflux transporters of Burkholderia cenocepacia in intrinsic antibiotic resistance | 1-gen-2009 | Buroni, Silvia; Pasca, MARIA ROSALIA; Flannagan, R. S.; Bazzini, S.; Milano, Anna; Bertani, I.; Venturi, V.; Valvano, M. A.; Riccardi, Giovanna | |
| Azole drug resistance in Mycobacterium tuberculosis | 1-gen-2007 | Provvedi, R.; Pasca, MARIA ROSALIA; Milano, Anna; Lucarelli, ANNA PAOLA; Manina, Giulia; Manganelli, R.; Riccardi, Giovanna | |
| Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5-MmpL5 efflux system | 1-gen-2009 | Milano, Anna; Pasca, MARIA ROSALIA; Provvedi, R.; Lucarelli, ANNA PAOLA; Manina, Giulia; DE JESUS LOPES RIBEIRO, A. L.; Manganelli, R.; Riccardi, Giovanna | |
| Benzothiazinones Are Suicide Inhibitors of Mycobacterial Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase DprE1. | 1-gen-2012 | Trefzer, C; Skovierová, H; Buroni, Silvia; Bobovská, A; Nenci, Simone; Molteni, Elisabetta; Pojer, F; Pasca, MARIA ROSALIA; Makarov, V; Cole, St; Riccardi, Giovanna; Mikušová, K; Johnsson, K. | |
| Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis | 1-gen-2009 | Makarov, V; Manina, Giulia; Mikusova, K; Möllmann, U; Ryabova, O; SAINT JOANIS, B; Dhar, N; Pasca, MARIA ROSALIA; Buroni, Silvia; Lucarelli, ANNA PAOLA; Milano, Anna; DE ROSSI, Edda; Belanova, M; Bobovska, A; Dianiskova, P; Kordulakova, J; Sala, C; Fullam, E; Schneider, P; Mckinney, Jd; Brodin, P; Christophe, T; Waddell, S; Butcher, P; Albrethsen, J; Rosenkrands, I; Brosch, R; Nandi, V; Bharath, S; Gaonkar, S; Shandil, Rk; Balasubramanian, V; Balganesh, T; Tyagi, S; Grosset, J; Riccardi, Giovanna; Cole, S. T. | |
| Biological and structural characterization of theMycobacterium smegmatis nitroreductase NfnB, and its rolein benzothiazinone resistance | 1-gen-2010 | Manina, Giulia; Bellinzoni, M; Pasca, MARIA ROSALIA; Neres, J; Milano, Anna; DE JESUS LOPES RIBEIRO, Al; Buroni, Silvia; Škovierová, H; Dianišková, P; Mikušová, K; Marák, J; Makarov, V; Giganti, D; Haouz, A; Lucarelli, ANNA PAOLA; Degiacomi, Giulia; Piazza, Aurora; Chiarelli, Laurent; DE ROSSI, Edda; Salina, E; Cole, St; Alzari, Pm; Riccardi, Giovanna | |
| Bombas de eflujo como trasportadores de membrana implicados en resistencia a antibióticos en micobacterias | 1-gen-2005 | Ramon Garcia, Santiago; Mick, Virginie; Buroni, Silvia; Arcesi, Fabio; Guglierame, Paola; Pasca, MARIA ROSALIA; Martin, Carlos; DE ROSSI, Edda; Ainsa, Jose | |
| CanB, a Druggable Cellular Target in Mycobacterium tuberculosis | 1-gen-2023 | Degiacomi, Giulia; Gianibbi, Beatrice; Recchia, Deborah; Stelitano, Giovanni; Truglio, Giuseppina Ivana; Marra, Paola; Stamilla, Alessandro; Makarov, Vadim; Chiarelli, Laurent Robert; Manetti, Fabrizio; Pasca, Maria Rosalia |