DEGIACOMI, GIULIA

DEGIACOMI, GIULIA  

DIPARTIMENTO DI BIOLOGIA E BIOTECNOLOGIE "LAZZARO SPALLANZANI"  

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Titolo Data di pubblicazione Autore(i) File
A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in Mycobacterium tuberculosis 1-gen-2021 Farjallah, Asma; Chiarelli, Laurent R; Forbak, Martin; Degiacomi, Giulia; Danel, Mathieu; Goncalves, Fernanda; Carayon, Chantal; Seguin, Cendrine; Fumagalli, Marco; Záhorszká, Monika; Vega, Elodie; Abid, Souhir; Grzegorzewicz, Anna; Jackson, Mary; Peixoto, Antonio; Korduláková, Jana; Pasca, Maria Rosalia; Lherbet, Christian; Chassaing, Stefan
A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK 1-gen-2018 Chiarelli, L; Mori, G; Orena, Bs; Esposito, M; Lane, T; de Lopes Jesus Ribeiro, Al; Degiacomi, G; Zemanova, J; Szadocka, S; Huszar, S; Palcekova, Z; Manfredi, M; Gosetti, F; Lelievre, J; Ballell, L; Kazakova, E; Makarov, V; Marengo, E; Mikusova, K; Cole, St; Riccardi, G; Ekins, S; Pasca, Mr
A New Benzothiazolthiazolidine Derivative, 11726172, Is Active In Vitro, In Vivo, and against Nonreplicating Cells of Mycobacterium tuberculosis 1-gen-2022 Salina, Elena G; Postiglione, Umberto; Chiarelli, Laurent R; Recchia, Deborah; Záhorszká, Monika; Lepioshkin, Alexander; Monakhova, Natalia; Pál, Adrian; Porta, Alessio; Zanoni, Giuseppe; Korduláková, Jana; Kazakova, Elena; Sassera, Davide; Pasca, Maria Rosalia; Makarov, Vadim; Degiacomi, Giulia
A phenotypic based target screening approach delivers new antitubercular CTP synthetase inhibitors 1-gen-2017 Esposito, Marta; Szadocka, Sára; Degiacomi, Giulia; Orena, BEATRICE SILVIA; Mori, Giorgia; Piano, Valentina; Boldrin, Francesca; Zemanova, Julia; Huszár, Stanislav; Barros, David; Ekins, Sean; Lelièvre, Joël; Manganelli, Riccardo; Mattevi, Andrea; Pasca, MARIA ROSALIA; Riccardi, Giovanna; Ballell, Lluis; Mikušová, Katarína; Chiarelli, Laurent
Age-related changes in PD-1 expression coincide with increased cytotoxic potential in Vδ2 T cells during infancy 1-gen-2021 Hsu, H.; Boudova, S.; Mvula, G.; Divala, T. H.; Rach, D.; Mungwira, R. G.; Boldrin, F.; Degiacomi, G.; Manganelli, R.; Laufer, M. K.; Cairo, C.
Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis 1-gen-2011 De Jesus Lopes Ribeiro, Al; Degiacomi, Giulia; Ewann, F; Buroni, Silvia; Incandela, Ml; Chiarelli, Laurent; Mori, G; Kim, J; Contreras Dominguez, M; Park, Ys; Han, Sj; Brodin, P; Valentini, Giovanna; Rizzi, M; Riccardi, Giovanna; Pasca, MARIA ROSALIA
Biological and structural characterization of theMycobacterium smegmatis nitroreductase NfnB, and its rolein benzothiazinone resistance 1-gen-2010 Manina, Giulia; Bellinzoni, M; Pasca, MARIA ROSALIA; Neres, J; Milano, Anna; DE JESUS LOPES RIBEIRO, Al; Buroni, Silvia; Škovierová, H; Dianišková, P; Mikušová, K; Marák, J; Makarov, V; Giganti, D; Haouz, A; Lucarelli, ANNA PAOLA; Degiacomi, Giulia; Piazza, Aurora; Chiarelli, Laurent; DE ROSSI, Edda; Salina, E; Cole, St; Alzari, Pm; Riccardi, Giovanna
CanB, a Druggable Cellular Target in Mycobacterium tuberculosis 1-gen-2023 Degiacomi, Giulia; Gianibbi, Beatrice; Recchia, Deborah; Stelitano, Giovanni; Truglio, Giuseppina Ivana; Marra, Paola; Stamilla, Alessandro; Makarov, Vadim; Chiarelli, Laurent Robert; Manetti, Fabrizio; Pasca, Maria Rosalia
Clinical Isolates of Mycobacterium tuberculosis in Four European Hospitals are Uniformly Susceptible to Benzothiazinones 1-gen-2010 Pasca, MARIA ROSALIA; Degiacomi, Giulia; Ribeiro, Al; Zara, Francesca; De Mori, P; Heym, B; Mirrione, M; Brerra, Roberto; Pagani, Laura; Pucillo, L; Troupioti, P; Makarov, V; Cole, St; Riccardi, Giovanna
Concomitant assessment of PD-1 and CD56 expression identifies subsets of resting cord blood Vδ2 T cells with disparate cytotoxic potential 1-gen-2024 Hsu, Haoting; Zanettini, Claudio; Coker, Modupe; Boudova, Sarah; Rach, David; Mvula, Godfrey; Divala, Titus H; Mungwira, Randy G; Boldrin, Francesca; Degiacomi, Giulia; Mazzabò, Laura Cioetto; Manganelli, Riccardo; Laufer, Miriam K; Zhang, Yuji; Marchionni, Luigi; Cairo, Cristiana
Decaprenylphosphoryl-beta-D-ribose 2’-epimerase from Mycobacterium tuberculosis is a magic drug target. 1-gen-2010 Buroni, Silvia; Manina, Giulia; Pasca, MARIA ROSALIA; DE JESUS LOPES RIBEIRO, ANA LUISA; Degiacomi, Giulia; DE ROSSI, Edda; Riccardi, Giovanna
Design and Synthesis of Pyrano[3,2-b]indolones Showing Antimycobacterial Activity 1-gen-2021 Monakhova, N.; Kordulakova, J.; Vocat, A.; Egorova, A.; Lepioshkin, A.; Salina, E. G.; Nosek, J.; Repkova, E.; Zemanova, J.; Jurdakova, H.; Gorova, R.; Roh, J.; Degiacomi, G.; Sammartino, J. C.; Pasca, M. R.; Cole, S. T.; Mikusova, K.; Makarov, V.
Design of Anti-infectious Agents from Lawsone in a Three-Component Reaction with Aldehydes and Isocyanides 1-gen-2022 Koumpoura, Christina L.; Nguyen, Michel; Bijani, Christian; Vendier, Laure; Salina, Elena G.; Buroni, Silvia; Degiacomi, Giulia; Cojean, Sandrine; Loiseau, Philippe M.; Benoit-Vical, Françoise; García-Sosa, Alfonso T.; Anne Robert, Null; Baltas, Michel
Distinct Effects of Moxifloxacin and Bedaquiline on Growing and 'Non-Culturable' Mycobacterium abscessus 1-gen-2023 Mulyukin, Andrey L; Recchia, Deborah; Kostrikina, Nadezhda A; Artyukhina, Maria V; Martini, Billy A; Stamilla, Alessandro; Degiacomi, Giulia; Salina, Elena G
Essentiality of mmpL3 and impact of its silencing on Mycobacterium tuberculosis gene expression 1-gen-2017 Degiacomi, G.; Benjak, A.; Madacki, J.; Boldrin, F.; Provvedi, R.; Palu, G.; Kordulakova, J.; Cole, S. T.; Manganelli, R.
Expanding the knowledge around antitubercular 5-(2-aminothiazol-4-yl)isoxazole-3-carboxamides: Hit-to-lead optimization and release of a novel antitubercular chemotype via scaffold derivatization 1-gen-2023 Girardini, Miriam; Ferlenghi, Francesca; Annunziato, Giannamaria; Degiacomi, Giulia; Papotti, Bianca; Marchi, Cinzia; Rasheed, Sari S; Contini, Anna; Pasca, Maria Rosalia; Vacondio, Federica; Evans, Joanna C; Dick, Thomas; Müller, Rolf; Costantino, Gabriele; Pieroni, Marco; Sammartino, José Camilla
Exploring the plasticity of the InhA substrate-binding site using new diaryl ether inhibitors 1-gen-2023 Tamhaev, R; Grosjean, E; Ahamed, H; Chebaiki, M; Rodriguez, F; Recchia, D; Degiacomi, G; Pasca, Mr; Maveyraud, L; Mourey, L; Lherbet, C
First triclosan-based macrocyclic inhibitors of InhA enzyme 1-gen-2020 Rodriguez, F; Saffon, N; Sammartino, Jc; Degiacomi, G; Pasca, Mr; Lherbet, C.
Functional investigation of the antitubercular drug target Decaprenylphosphoryl-β-D-ribofuranose-2-epimerase DprE1/DprE2 complex 1-gen-2022 Sammartino, Josè Camilla; Morici, Martino; Stelitano, Giovanni; Degiacomi, Giulia; Riccardi, Giovanna; Chiarelli, Laurent Roberto
GarA is an essential regulator of metabolism in mycobacterium tuberculosis 1-gen-2013 Ventura, M.; Rieck, B.; Boldrin, F.; Degiacomi, G.; Bellinzoni, M.; Barilone, N.; Alzaidi, F.; Alzari, P. M.; Manganelli, R.; O'Hare, H. M.