DEGIACOMI, GIULIA

DEGIACOMI, GIULIA  

DIPARTIMENTO DI BIOLOGIA E BIOTECNOLOGIE "LAZZARO SPALLANZANI"  

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Age-related changes in PD-1 expression coincide with increased cytotoxic potential in Vδ2 T cells during infancy 1-gen-2021 Hsu, H.; Boudova, S.; Mvula, G.; Divala, T. H.; Rach, D.; Mungwira, R. G.; Boldrin, F.; Degiacomi, G.; Manganelli, R.; Laufer, M. K.; Cairo, C.
Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis 1-gen-2011 De Jesus Lopes Ribeiro, Al; Degiacomi, Giulia; Ewann, F; Buroni, Silvia; Incandela, Ml; Chiarelli, Laurent; Mori, G; Kim, J; Contreras Dominguez, M; Park, Ys; Han, Sj; Brodin, P; Valentini, Giovanna; Rizzi, M; Riccardi, Giovanna; Pasca, MARIA ROSALIA
The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis 1-gen-2017 Rosado, L. A.; Wahni, K.; Degiacomi, G.; Pedre, B.; Young, D.; De la Rubia, A. G.; Boldrin, F.; Martens, E.; Marcos-Pascual, L.; Sancho-Vaello, E.; Albesa-Jove, D.; Provvedi, R.; Martin, C.; Makarov, V.; Versees, W.; Verniest, G.; Guerin, M. E.; Mateos, L. M.; Manganelli, R.; Messens, J.
The antimalarial mefloquine shows activity against mycobacterium abscessus, inhibiting mycolic acid metabolism 1-gen-2021 Degiacomi, G.; Chiarelli, L. R.; Recchia, D.; Petricci, E.; Gianibbi, B.; Fiscarelli, E. V.; Fattorini, L.; Manetti, F.; Pasca, M. R.
Biological and structural characterization of theMycobacterium smegmatis nitroreductase NfnB, and its rolein benzothiazinone resistance 1-gen-2010 Manina, Giulia; Bellinzoni, M; Pasca, MARIA ROSALIA; Neres, J; Milano, Anna; DE JESUS LOPES RIBEIRO, Al; Buroni, Silvia; Škovierová, H; Dianišková, P; Mikušová, K; Marák, J; Makarov, V; Giganti, D; Haouz, A; Lucarelli, ANNA PAOLA; Degiacomi, Giulia; Piazza, Aurora; Chiarelli, Laurent; DE ROSSI, Edda; Salina, E; Cole, St; Alzari, Pm; Riccardi, Giovanna
Clinical Isolates of Mycobacterium tuberculosis in Four European Hospitals are Uniformly Susceptible to Benzothiazinones 1-gen-2010 Pasca, MARIA ROSALIA; Degiacomi, Giulia; Ribeiro, Al; Zara, Francesca; De Mori, P; Heym, B; Mirrione, M; Brerra, Roberto; Pagani, Laura; Pucillo, L; Troupioti, P; Makarov, V; Cole, St; Riccardi, Giovanna
A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in Mycobacterium tuberculosis 1-gen-2021 Farjallah, Asma; Chiarelli, Laurent R; Forbak, Martin; Degiacomi, Giulia; Danel, Mathieu; Goncalves, Fernanda; Carayon, Chantal; Seguin, Cendrine; Fumagalli, Marco; Záhorszká, Monika; Vega, Elodie; Abid, Souhir; Grzegorzewicz, Anna; Jackson, Mary; Peixoto, Antonio; Korduláková, Jana; Pasca, Maria Rosalia; Lherbet, Christian; Chassaing, Stefan
Decaprenylphosphoryl-beta-D-ribose 2’-epimerase from Mycobacterium tuberculosis is a magic drug target. 1-gen-2010 Buroni, Silvia; Manina, Giulia; Pasca, MARIA ROSALIA; DE JESUS LOPES RIBEIRO, ANA LUISA; Degiacomi, Giulia; DE ROSSI, Edda; Riccardi, Giovanna
Design and Synthesis of Pyrano[3,2-b]indolones Showing Antimycobacterial Activity 1-gen-2021 Monakhova, N.; Kordulakova, J.; Vocat, A.; Egorova, A.; Lepioshkin, A.; Salina, E. G.; Nosek, J.; Repkova, E.; Zemanova, J.; Jurdakova, H.; Gorova, R.; Roh, J.; Degiacomi, G.; Sammartino, J. C.; Pasca, M. R.; Cole, S. T.; Mikusova, K.; Makarov, V.
Design of Anti-infectious Agents from Lawsone in a Three-Component Reaction with Aldehydes and Isocyanides 1-gen-2022 Koumpoura, Christina L.; Nguyen, Michel; Bijani, Christian; Vendier, Laure; Salina, Elena G.; Buroni, Silvia; Degiacomi, Giulia; Cojean, Sandrine; Loiseau, Philippe M.; Benoit-Vical, Françoise; García-Sosa, Alfonso T.; Anne Robert, Null; Baltas, Michel
Essentiality of mmpL3 and impact of its silencing on Mycobacterium tuberculosis gene expression 1-gen-2017 Degiacomi, G.; Benjak, A.; Madacki, J.; Boldrin, F.; Provvedi, R.; Palu, G.; Kordulakova, J.; Cole, S. T.; Manganelli, R.
First triclosan-based macrocyclic inhibitors of InhA enzyme 1-gen-2020 Rodriguez, F; Saffon, N; Sammartino, Jc; Degiacomi, G; Pasca, Mr; Lherbet, C.
Functional investigation of the antitubercular drug target Decaprenylphosphoryl-β-D-ribofuranose-2-epimerase DprE1/DprE2 complex 1-gen-2022 Sammartino, Josè Camilla; Morici, Martino; Stelitano, Giovanni; Degiacomi, Giulia; Riccardi, Giovanna; Chiarelli, Laurent Roberto
GarA is an essential regulator of metabolism in mycobacterium tuberculosis 1-gen-2013 Ventura, M.; Rieck, B.; Boldrin, F.; Degiacomi, G.; Bellinzoni, M.; Barilone, N.; Alzaidi, F.; Alzari, P. M.; Manganelli, R.; O'Hare, H. M.
In vitro Study of Bedaquiline Resistance in Mycobacterium tuberculosis Multi-Drug Resistant Clinical Isolates. 1-gen-2020 Degiacomi, G; Sammartino, Jc; Sinigiani, V; Marra, P; Urbani, A; Pasca, Mr.
Micrococcin P1 – A bactericidal thiopeptide active against Mycobacterium tuberculosis 1-gen-2016 Degiacomi, G.; Personne, Y.; Mondesert, G.; Ge, X.; Mandava, C. S.; Hartkoorn, R. C.; Boldrin, F.; Goel, P.; Peisker, K.; Benjak, A.; Barrio, M. B.; Ventura, M.; Brown, A. C.; Leblanc, V.; Bauer, A.; Sanyal, S.; Cole, S. T.; Lagrange, S.; Parish, T.; Manganelli, R.
A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK 1-gen-2018 Chiarelli, L; Mori, G; Orena, Bs; Esposito, M; Lane, T; de Lopes Jesus Ribeiro, Al; Degiacomi, G; Zemanova, J; Szadocka, S; Huszar, S; Palcekova, Z; Manfredi, M; Gosetti, F; Lelievre, J; Ballell, L; Kazakova, E; Makarov, V; Marengo, E; Mikusova, K; Cole, St; Riccardi, G; Ekins, S; Pasca, Mr
Mycobacterium abscessus, an Emerging and Worrisome Pathogen among Cystic Fibrosis Patients. 1-gen-2019 Degiacomi, G; Sammartino, Jc; Chiarelli, Lr; Riabova, O; Makarov, V; Pasca, Mr.
A New Benzothiazolthiazolidine Derivative, 11726172, Is Active In Vitro, In Vivo, and against Nonreplicating Cells of Mycobacterium tuberculosis 1-gen-2022 Salina, Elena G; Postiglione, Umberto; Chiarelli, Laurent R; Recchia, Deborah; Záhorszká, Monika; Lepioshkin, Alexander; Monakhova, Natalia; Pál, Adrian; Porta, Alessio; Zanoni, Giuseppe; Korduláková, Jana; Kazakova, Elena; Sassera, Davide; Pasca, Maria Rosalia; Makarov, Vadim; Degiacomi, Giulia
New insights into the mechanism of action of the thienopyrimidine antitubercular prodrug TP053 1-gen-2020 Chiarelli, Lr; Salina, Eg; Mori, G; Azhikina, T; Riabova, O; Lepioshkin, A; Grigorov, A; Forbak, M; Madacki, J; Orena, Bs; Manfredi, M; Gosetti, F; Buzzi, A; Degiacomi, G; Sammartino, Jc; Marengo, E; Korduláková, J; Riccardi, G; Mikušová, K; Makarov, V; Pasca, Mr.