TORTORICI, MARCELLO
TORTORICI, MARCELLO
DIPARTIMENTO DI BIOLOGIA E BIOTECNOLOGIE "LAZZARO SPALLANZANI"
Expanding the druggable space of the LSD1/CoREST epigenetic target: new potential binding regions for drug-like molecules, peptides, protein partners, and chromatin.
2013-01-01 Robertson, Jc; Hurley, Nc; Tortorici, Marcello; Ciossani, Giuseppe; Borrello, Mt; Vellore, Na; Ganesan, A; Mattevi, Andrea; Baron, R.
Interplay among nucleosomal DNA, histone tails, and corepressor CoREST underlies LSD1-mediated H3 demethylation.
2015-01-01 Pilotto, Simona; Speranzini, Valentina; Tortorici, Marcello; Durand, D; Fish, A; Valente, S; Forneris, Federico; Mai, Antonello; Sixma, Tk; Vachette, P; Mattevi, Andrea
Molecular Insights into Human Monoamine Oxidase B Inhibition by the Glitazone Antidiabetes Drugs
2012-01-01 Binda, Claudia; Aldeco, M; Geldenhuys, Wj; Tortorici, Marcello; Mattevi, Andrea; Edmondson, De
Molecular Mimicry and Ligand Recognition in Binding and Catalysis by the Histone Demethylase LSD1-CoREST Complex
2011-01-01 Baron, R; Binda, Claudia; Tortorici, Marcello; Mccammon, Ja; Mattevi, Andrea
Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities.
2014-01-01 Rotili, D; Tomassi, S; Conte, M; Benedetti, R; Tortorici, Marcello; Ciossani, Giuseppe; Valente, S; Marrocco, B; Labella, D; Novellino, E; Mattevi, Andrea; Altucci, L; Tumber, A; Yapp, C; King, On; Hopkinson, Rj; Kawamura, A; Schofield, Cj; Mai, A.
Phosphorylation of neuronal Lysine-Specific Demethylase 1LSD1/KDM1A impairs transcriptional repression by regulating interaction with CoREST and histone deacetylases HDAC1/2.
2013-01-01 Toffolo, E; Rusconi, F; Paganini, L; Tortorici, Marcello; Pilotto, Simona; Heise, C; Verpelli, C; Tedeschi, G; Maffioli, E; Sala, C; Mattevi, Andrea; Battaglioli, E.
Protein Recognition by Short Peptide Reversible Inhibitors of the Chromatin-Modifying LSD1/CoREST Lysine Demethylase.
2013-01-01 Tortorici, Marcello; Borrello, Mt; Tardugno, M; Chiarelli, Laurent; Pilotto, Simona; Ciossani, Giuseppe; Vellore, Na; Bailey, Sg; Cowan, J; O'Connell, M; Crabb, Sj; Packham, G; Mai, A; Baron, R; Ganesan, A; Mattevi, Andrea
Synthesis, biological activity and mechanistic insights of 1-substituted cyclopropylamine derivatives: a novel class of irreversible inhibitors of histone demethylase KDM1A.
2014-01-01 Vianello, P; Botrugno, Oa; Cappa, A; Ciossani, Giuseppe; Dessanti, P; Mai, A; Mattevi, Andrea; Meroni, G; Minucci, S; Thaler, F; Tortorici, Marcello; Trifiró, P; Valente, S; Villa, M; Varasi, M; Mercurio, C.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Expanding the druggable space of the LSD1/CoREST epigenetic target: new potential binding regions for drug-like molecules, peptides, protein partners, and chromatin. | 1-gen-2013 | Robertson, Jc; Hurley, Nc; Tortorici, Marcello; Ciossani, Giuseppe; Borrello, Mt; Vellore, Na; Ganesan, A; Mattevi, Andrea; Baron, R. | |
| Interplay among nucleosomal DNA, histone tails, and corepressor CoREST underlies LSD1-mediated H3 demethylation. | 1-gen-2015 | Pilotto, Simona; Speranzini, Valentina; Tortorici, Marcello; Durand, D; Fish, A; Valente, S; Forneris, Federico; Mai, Antonello; Sixma, Tk; Vachette, P; Mattevi, Andrea | |
| Molecular Insights into Human Monoamine Oxidase B Inhibition by the Glitazone Antidiabetes Drugs | 1-gen-2012 | Binda, Claudia; Aldeco, M; Geldenhuys, Wj; Tortorici, Marcello; Mattevi, Andrea; Edmondson, De | |
| Molecular Mimicry and Ligand Recognition in Binding and Catalysis by the Histone Demethylase LSD1-CoREST Complex | 1-gen-2011 | Baron, R; Binda, Claudia; Tortorici, Marcello; Mccammon, Ja; Mattevi, Andrea | |
| Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities. | 1-gen-2014 | Rotili, D; Tomassi, S; Conte, M; Benedetti, R; Tortorici, Marcello; Ciossani, Giuseppe; Valente, S; Marrocco, B; Labella, D; Novellino, E; Mattevi, Andrea; Altucci, L; Tumber, A; Yapp, C; King, On; Hopkinson, Rj; Kawamura, A; Schofield, Cj; Mai, A. | |
| Phosphorylation of neuronal Lysine-Specific Demethylase 1LSD1/KDM1A impairs transcriptional repression by regulating interaction with CoREST and histone deacetylases HDAC1/2. | 1-gen-2013 | Toffolo, E; Rusconi, F; Paganini, L; Tortorici, Marcello; Pilotto, Simona; Heise, C; Verpelli, C; Tedeschi, G; Maffioli, E; Sala, C; Mattevi, Andrea; Battaglioli, E. | |
| Protein Recognition by Short Peptide Reversible Inhibitors of the Chromatin-Modifying LSD1/CoREST Lysine Demethylase. | 1-gen-2013 | Tortorici, Marcello; Borrello, Mt; Tardugno, M; Chiarelli, Laurent; Pilotto, Simona; Ciossani, Giuseppe; Vellore, Na; Bailey, Sg; Cowan, J; O'Connell, M; Crabb, Sj; Packham, G; Mai, A; Baron, R; Ganesan, A; Mattevi, Andrea | |
| Synthesis, biological activity and mechanistic insights of 1-substituted cyclopropylamine derivatives: a novel class of irreversible inhibitors of histone demethylase KDM1A. | 1-gen-2014 | Vianello, P; Botrugno, Oa; Cappa, A; Ciossani, Giuseppe; Dessanti, P; Mai, A; Mattevi, Andrea; Meroni, G; Minucci, S; Thaler, F; Tortorici, Marcello; Trifiró, P; Valente, S; Villa, M; Varasi, M; Mercurio, C. |