COLOMBO, GIORGIO

COLOMBO, GIORGIO  

DIPARTIMENTO DI CHIMICA  

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Risultati 1 - 20 di 253 (tempo di esecuzione: 0.1 secondi).
Titolo Data di pubblicazione Autore(i) File
2 `-O-Alkyl Derivatives and 5 `-Analogues of 5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (AICAR) as Potential Hsp90 Inhibitors 1-gen-2009 Bracci, Antonio; Colombo, Giorgio; Ronchetti, Fiamma; Compostella, Federica
3D-QSAR-Assisted Design, Synthesis, and Evaluation of Novobiocin Analogues 1-gen-2013 Zhao, Huiping; Moroni, Elisabetta; Yan, Bin; Colombo, Giorgio; Blagg, Brian S. J.
A Computational Assay of Estrogen Receptor alpha Antagonists Reveals the Key Common Structural Traits of Drugs Effectively Fighting Refractory Breast Cancers 1-gen-2018 Pavlin, Matic; Spinello, Angelo; Pennati, Marzia; Zaffaroni, Nadia; Gobbi, Silvia; Bisi, Alessandra; Colombo, Giorgio; Magistrato, Alessandra
A decoy set for the thermostable subdomain from chicken villin headpiece, comparison of different free energy estimators 1-gen-2005 Fogolari, F; Tosatto, Sce; Colombo, G
A dynamic perspective on the molecular recognition of chitooligosaccharide ligands by hevein domains 1-gen-2005 Colombo, G; Meli, M; Canada, J; Asensio, Jl; Jimenez-Barbero, J
A Fe2+-dependent self-inhibited state influences the druggability of human collagen lysyl hydroxylase (LH/PLOD) enzymes 1-gen-2022 Scietti, Luigi; Moroni, Elisabetta; Mattoteia, Daiana; Fumagalli, Marco; De Marco, Matteo; Negro, Lisa; Chiapparino, Antonella; Serapian, Stefano A.; De Giorgi, Francesca; Faravelli, Silvia; Colombo, Giorgio; Forneris, Federico
A Hamiltonian Replica Exchange Molecular Dynamics (MD) Method for the Study of Folding, Based on the Analysis of the Stabilization Determinants of Proteins 1-gen-2013 Meli, Massimiliano; Colombo, Giorgio
A Local Allosteric Network in Heat Shock Protein 70 (Hsp70) Links Inhibitor Binding to Enzyme Activity and Distal Protein-Protein Interactions 1-gen-2018 Rinaldi, Silvia; Assimon, Victoria A.; Young, Zapporah T.; Morra, Giulia; Shao, Hao; Taylor, Isabelle R.; Gestwicki, Jason E.; Colombo, Giorgio
A Molecular Dynamics Study of the Interaction of D-Peptide Amyloid Inhibitors with Their Target Sequence Reveals a Potential Inhibitory Pharmacophore Conformation 1-gen-2008 Esteras-Chopo, Alexandra; Morra, Giulia; Moroni, Elisabetta; Serrano, Luis; de la Paz Manuela, Lopez; Colombo, Giorgio
A Multiscale Approach to Characterize the Early Aggregation Steps of the Amyloid-Forming Peptide GNNQQNY from the Yeast Prion Sup-35 1-gen-2011 Nasica-Labouze, Jessica; Meli, Massimiliano; Derreumaux, Philippe; Colombo, Giorgio; Rousseau, Normand
A protease-resistant Escherichia coli asparaginase with outstanding stability and enhanced anti-leukaemic activity in vitro 1-gen-2017 Maggi, Maristella; Mittelman Steven, D.; Parmentier Jean, Hugues; Colombo, Giorgio; Meli, Massimiliano; Whitmire Jeannette, Marie; Merrell D., Scott; Whitelegge, Julian; Scotti, Claudia
A Structure-Based Strategy for Epitope Discovery in Burkholderia pseudomallei OppA Antigen 1-gen-2013 Lascaux, Patricia; Peri, Claudio; Ferrer-Navarro, Mario; Gourlay Louise, J; Gori, Alessandro; Conchillo-Sole, Oscar; Rinchai, Darawan; Lertmemongkolchai, Ganjana; Longhi, Renato; Daura, Xavier; Colombo, Giorgio; Bolognesi, Martino
Ab initio protein structure prediction with a dipeptide-assembly evolutionary algorithm 1-gen-2007 Bazzoli, A; Colombo, G; Tettamanzi, A
Activation of Hsp90 Enzymatic Activity and Conformational Dynamics through Rationally Designed Allosteric Ligands 1-gen-2015 Sattin, Sara; Tao, Jiahui; Vettoretti, Gerolamo; Moroni, Elisabetta; Pennati, Marzia; Lopergolo, Alessia; Morelli, Laura; Bugatti, Antonella; Zuehlke, Abbey; Moses, Mike; Prince, Thomas; Kijima, Toshiki; Beebe, Kristin; Rusnati, Marco; Neckers, Len; Zaffaroni, Nadia; Agard David, A; Bernardi, Anna; Colombo, Giorgio
ADAMDEC1 maintains a growth factor signaling loop in cancer stem cells 1-gen-2019 Jimenez-Pascual, A.; Hale, J. S.; Kordowski, A.; Pugh, J.; Silver, D. J.; Bayik, D.; Roversi, G.; Alban, T. J.; Rao, S.; Chen, R.; Mcintyre, T. M.; Colombo, G.; Taraboletti, G.; Holmberg, K. O.; Forsberg-Nilsson, K.; Lathia, J. D.; Siebzehnrubl, F. A.
AICAR: A rational identified small molecule targeting Hsp90 chaperone function in cancer cells 1-gen-2006 Pennati, M; Meli, M; Curto, M; Daidone, Mg; Plescia, J; Toba, S; Altieri, Dc; Zaffaroni, N; Colombo, G
All-atom folding simulations of the villin headpiece from stochastically selected coarse-grained structures 1-gen-2004 De Mori, Gms; Micheletti, C; Colombo, G
Allosteric modulators of Hsp90 and Hsp70: Dynamics meets Function through Structure-Based Drug Design 1-gen-2018 Ferraro, M; D'Annessa, I; Moroni, E; Morra, G; Paladino, A; Rinaldi, S; Compostella, F; Colombo, G
Allosteric Regulation Points Control the Conformational Dynamics of the Molecular Chaperone Hsp90 1-gen-2016 Rehn, Alexandra; Moroni, Elisabetta; Zierer Bettina, K; Tippel, Franziska; Morra, Giulia; John, Christine; Richter, Klaus; Colombo, Giorgio; Buchner, Johannes
AlphaFold predicted structure of the Hsp90-like domains of the neurodegeneration linked protein sacsin reveals key residues for ATPase activity 1-gen-2022 Perna, Laura; Castelli, Matteo; Frasnetti, Elena; Romano, Lisa E L; Colombo, Giorgio; Prodromou, Chrisostomos; Chapple, J Paul