Irradiation of the 6,8-difluoroquinolone antibiotic lomefloxacin causes selective heterolytic defluorination from position 8 and leads to products rationalized as arising from the cation either via nucleophile addition or intramolecular carbene C–H insertion and hydrogen transfer.
The photochemistry of lomefloxacin. An aromatic carbene as the key intermediate in both photodecomposition and photocarcinogenesis
FASANI, ELISA;MELLA, MARIELLA;FAGNONI, MAURIZIO;ALBINI, ANGELO
1997-01-01
Abstract
Irradiation of the 6,8-difluoroquinolone antibiotic lomefloxacin causes selective heterolytic defluorination from position 8 and leads to products rationalized as arising from the cation either via nucleophile addition or intramolecular carbene C–H insertion and hydrogen transfer.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
