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Spin-orbit coupling and beyond in Chiral-Induced Spin Selectivity

Chiral-Induced Spin Selectivity (CISS) describes the emergence of spin-polarized electron transport in chiral systems without magnetic fields—a remarkable effect in light-element materials with weak intrinsic spin–orbit coupling (SOC). This mini-review analyzes the microscopic origins of CISS, highlighting how molecular chirality, local electric fields, and dynamic distortions enhance effective SOC and drive spindependent transport. We critically assess existing models in terms of their s...

Evaluation of a smartphone application in controlling oral hygiene and orthodontic urgencies in pediatric patients with rapid palatal expander: randomized clinical trial

Background: The present randomized clinical trial aimed to evaluate the potential effects of an orthodontic smartphone application (Ortodontika) in addition to verbal instructions for the improvement of pediatric patients’ oral health and the reduction of orthodontic urgencies in the first 6 months of hyrax rapid palatal expander (RPE) treatment. Methods: Patients aged 6–14 years old were enrolled and modified gingival index (MGI), bleeding index (BI), and plaque index (PI) were recorded at t...

Evaluation of salivary pH in pediatric patients undergoing orthodontic treatment with rapid palatal expander: cross-sectional study

Background: Orthodontic appliances increase the difficulty of maintaining oral hygiene due to their size and complexity. This study aimed to evaluate salivary pH and buffer capacity in pediatric patients aged 6–14 years using the Saliva-Check Buffer test comparing two groups: patients who have completed dental treatments but have not yet started the orthodontic treatment (control group), and those who have been undergoing orthodontic treatment with rapid palatal expander (RPE) for at least si...

Homocysteine levels do not impact cognitive profile in frontotemporal dementia.

Background: This study aimed at investigating whether high plasma homocysteine (Hcy) levels affect specific cognitive functions in individuals with Frontotemporal Dementia (FTD). While Hcy is a well-established risk factor for cerebrovascular disorders and Alzheimer’s Disease, its role in other neurodegenerative dementias remains unclear. Furthermore, it is not known whether elevated Hcy levels contribute to a generalized cognitive decline or selectively impair specific cognitive domains. Thi...

Naphthalene diimide-naphthalimide dyads promote telomere damage by selectively targeting multimeric G-quadruplexes

G-quadruplex (G4) nucleic acid ligands have attracted significant attention as putative anticancer agents for selectively stabilizing telomeric structures. In our pursuit of targeting the most biologically relevant telomeric structures, we have investigated a new class of naphthalene diimide (NDI)-based ligands designed to bind multimeric G4s. The NDI unit covalently linked with one 1,8-naphthalimide (NI) moiety, results in ligands able to fold into a sandwich-like conformation fitting into t...

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