The first genetic, in vivo, and in vitro evidences that YrxA is the regulator of NAD de novo biosynthesis in Bacillus subtilis are hereby reported. The protein is essential to the transcription repression of the divergent operons nadBCA and nifS-yrxA in the presence of nicotinic acid and binds to their shared operator-promoter region.
YrxA is the transcriptional regulator that represses de novo NAD biosynthesis in Bacillus subtilis
ROSSOLILLO, PAOLA;MARINONI, ILARIA;GALLI, ELISA;ALBERTINI, ALESSANDRA
2005-01-01
Abstract
The first genetic, in vivo, and in vitro evidences that YrxA is the regulator of NAD de novo biosynthesis in Bacillus subtilis are hereby reported. The protein is essential to the transcription repression of the divergent operons nadBCA and nifS-yrxA in the presence of nicotinic acid and binds to their shared operator-promoter region.File in questo prodotto:
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