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The first genetic, in vivo, and in vitro evidences that YrxA is the regulator of NAD de novo biosynthesis in Bacillus subtilis are hereby reported. The protein is essential to the transcription repression of the divergent operons nadBCA and nifS-yrxA in the presence of nicotinic acid and binds to their shared operator-promoter region.

YrxA is the transcriptional regulator that represses de novo NAD biosynthesis in Bacillus subtilis

ROSSOLILLO, PAOLA;MARINONI, ILARIA;GALLI, ELISA;ALBERTINI, ALESSANDRA
2005-01-01

Abstract

The first genetic, in vivo, and in vitro evidences that YrxA is the regulator of NAD de novo biosynthesis in Bacillus subtilis are hereby reported. The protein is essential to the transcription repression of the divergent operons nadBCA and nifS-yrxA in the presence of nicotinic acid and binds to their shared operator-promoter region.
2005
Molecular Biology & Genetics considers all aspects of basic and applied genetics, including molecular genetics, prokaryotic and eukaryotic gene expression, mechanisms of mutagenesis, structure, function and regulation of genetic material. Also included are resources concerned with clinical genetics, patterns of inheritance, genetic cause, and screening and treatment of disease. Resources dealing specifically with developmentally regulated gene expression, or with signal transduction pathways that modulate gene expression at the cellular level are excluded and are covered in the Cell and Developmental Biology category.
JOURNAL OF BACTERIOLOGY
sì
WOS:000232509500034
2-s2.0-26444568675
Esperti anonimi
Inglese
Internazionale
STAMPA
187
20
7155
7160
6
Tematica Ex SIR: Regolazione dell'espressione genica in Bacillus subtilis (Classif. Ex SIR:Articoli su riviste ISI ).
BACILLUS SUBTILIS; TRANSCRIPTIONAL REGULATION; NAD; DE NOVO SYNTHESIS
http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=1251630&blobtype=pdf
5
info:eu-repo/semantics/article
262
Rossolillo, Paola; Marinoni, Ilaria; Galli, Elisa; Colosimo, A; Albertini, Alessandra
1 Contributo su Rivista::1.1 Articolo in rivista
none
1.1 Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/109958
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