Interestingly, after JAK2, our observation on allelic imbalance of CALR mutations describes the second such case involved in MPN pathogenesis. It remains to be seen whether other cancer-associated loci exhibit biases in the acquisition of somatic mutations similar to JAK2 and CALR in MPN.
Allelic imbalance in CALR somatic mutagenesis
RUMI, ELISA;CAZZOLA, MARIO;
2015-01-01
Abstract
Interestingly, after JAK2, our observation on allelic imbalance of CALR mutations describes the second such case involved in MPN pathogenesis. It remains to be seen whether other cancer-associated loci exhibit biases in the acquisition of somatic mutations similar to JAK2 and CALR in MPN.File in questo prodotto:
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