This study examined the developmental toxicity of styrene, an important occupational chemical, and its metabolite, styrene oxide. Two in vitro culture systems, micromass cell culture and whole embryo culture, were used. Styrene oxide produced considerable toxicity in both cell culture systems whereas styrene alone had minimal effects even when tested at high concentrations.

Effects of styrene oxide on differentiation and viability of rodent embryo cultures

MANZO, LUIGI;
1994-01-01

Abstract

This study examined the developmental toxicity of styrene, an important occupational chemical, and its metabolite, styrene oxide. Two in vitro culture systems, micromass cell culture and whole embryo culture, were used. Styrene oxide produced considerable toxicity in both cell culture systems whereas styrene alone had minimal effects even when tested at high concentrations.
1994
The Pharmacology/Toxicology category covers resources on all aspects of clinical pharmacology and toxicology including psycho-pharmacology, pharmacokinetics, pharmacotherapy, drug monitoring and drug safety, chemotherapy, clinical and hospital pharmacy, and clinical trials.
Sì, ma tipo non specificato
Internazionale
STAMPA
128
25
35
11
Studio condotto in collaborazione con University of Washington, Seattle WA USA.
Styrene; styrene oxide; embryotoxicity; reproductive toxicity; in vitro
5
info:eu-repo/semantics/article
262
Gregotti, C; Kirby, Z; Manzo, Luigi; Costa, Lg; Faustman, E. M.
1 Contributo su Rivista::1.1 Articolo in rivista
none
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/110841
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