Interaction of chemicals with cerebral neurotransmitters, neurotransmitter receptors, and second messengers are often accompanied by similar changes in non-neural tissues and peripheral blood cells. Based on this notion, methods using easily accessible cells such as peripheral blood lymphocytes and platelets can be used as indirect biomarkers of chemically-induced neurotoxicity.

Mechanisms of neurotoxicity. Applications to human biomonitoring

MANZO, LUIGI;
1995-01-01

Abstract

Interaction of chemicals with cerebral neurotransmitters, neurotransmitter receptors, and second messengers are often accompanied by similar changes in non-neural tissues and peripheral blood cells. Based on this notion, methods using easily accessible cells such as peripheral blood lymphocytes and platelets can be used as indirect biomarkers of chemically-induced neurotoxicity.
1995
The Pharmacology/Toxicology category covers resources on all aspects of clinical pharmacology and toxicology including psycho-pharmacology, pharmacokinetics, pharmacotherapy, drug monitoring and drug safety, chemotherapy, clinical and hospital pharmacy, and clinical trials.
Sì, ma tipo non specificato
Inglese
Internazionale
77
63
72
10
Studio condotto in collaborazione con Karolinska Institute Stockholm e University of Washington, Seattle WA USA.
Biomarkers; platelet monoamine oxidase B; lymphocyte muscarinic receptors; neurotoxicity.
6
info:eu-repo/semantics/article
262
Manzo, Luigi; Castoldi, Af; Coccini, T; Rossi, Ad; Nicotera, P; Costa, L. G.
1 Contributo su Rivista::1.1 Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/110843
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