The results of this study suggest that acrylamide may be effective per se in causing peripheral nervous system damage in rats after repeated exposure to toxic doses (25-50 mg/gkg/day) whereas other toxic effects of this agent, such as reproductive toxicity appear to be mediated by the metabolite glycidamide.

Comparative studies on the neuro- and reproductive toxicity of acrylamide and its epoxide metabolite glycidamide in the rat.

MANZO, LUIGI;
1992

Abstract

The results of this study suggest that acrylamide may be effective per se in causing peripheral nervous system damage in rats after repeated exposure to toxic doses (25-50 mg/gkg/day) whereas other toxic effects of this agent, such as reproductive toxicity appear to be mediated by the metabolite glycidamide.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11571/110853
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