The results of this study suggest that acrylamide may be effective per se in causing peripheral nervous system damage in rats after repeated exposure to toxic doses (25-50 mg/gkg/day) whereas other toxic effects of this agent, such as reproductive toxicity appear to be mediated by the metabolite glycidamide.
Comparative studies on the neuro- and reproductive toxicity of acrylamide and its epoxide metabolite glycidamide in the rat.
MANZO, LUIGI;
1992-01-01
Abstract
The results of this study suggest that acrylamide may be effective per se in causing peripheral nervous system damage in rats after repeated exposure to toxic doses (25-50 mg/gkg/day) whereas other toxic effects of this agent, such as reproductive toxicity appear to be mediated by the metabolite glycidamide.File in questo prodotto:
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