In this study, ethanol promoted apoptotic cell death of cultured cerebellar neurons by selectively inhibiting the neurotrophic effect of NMDA and carbachol. This finding may have implications for the toxicity of prenatal ethanol exposure on the developing cerebellum.

Ethanol selectively interferes with the trophic action of NMDA and carbachol on cultured cerebellar granule cells undergoing apoptosis

MANZO, LUIGI
1999-01-01

Abstract

In this study, ethanol promoted apoptotic cell death of cultured cerebellar neurons by selectively inhibiting the neurotrophic effect of NMDA and carbachol. This finding may have implications for the toxicity of prenatal ethanol exposure on the developing cerebellum.
1999
The Pharmacology/Toxicology category covers resources on all aspects of clinical pharmacology and toxicology including psycho-pharmacology, pharmacokinetics, pharmacotherapy, drug monitoring and drug safety, chemotherapy, clinical and hospital pharmacy, and clinical trials.
Sì, ma tipo non specificato
Inglese
Internazionale
111
279
289
11
Studio condotto in collaborazione con University of Washington, Seattle WA USA
Ethanol; neurotoxicity; cerebellum; NMDA; apoptosis
5
info:eu-repo/semantics/article
262
Castoldi, Af; Barni, S; Randine, G; Costa, Lg; Manzo, Luigi
1 Contributo su Rivista::1.1 Articolo in rivista
none
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/110964
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