the etiologic diagnosis of pediatric chronic urticaria is quite challenging, as a minority of cases can be associated to specific triggers. Thus, more than 50% of chronic urticaria in children are labeled as idiopathic. Several evidences supported an autoimmune pathogenesis in 30-40% of patients with idiopathic (or spontaneous) chronic urticaria in adults, where the diagnosis of Autoimmune Chronic Urticaria should include in vivo and in vitro tests, revealing the presence of autoantibodies against high-affinity IgE receptors mainly, as stated by the majority of guidelines.
Spontaneous (Autoimmune?) Chronic Urticaria in children: current evidences, diagnostic pitfalls and therapeutical management
MARSEGLIA, GIAN LUIGI;DE AMICI, MARA
2016-01-01
Abstract
the etiologic diagnosis of pediatric chronic urticaria is quite challenging, as a minority of cases can be associated to specific triggers. Thus, more than 50% of chronic urticaria in children are labeled as idiopathic. Several evidences supported an autoimmune pathogenesis in 30-40% of patients with idiopathic (or spontaneous) chronic urticaria in adults, where the diagnosis of Autoimmune Chronic Urticaria should include in vivo and in vitro tests, revealing the presence of autoantibodies against high-affinity IgE receptors mainly, as stated by the majority of guidelines.File in questo prodotto:
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