Obesity is associated with a low-grade inflammatory state, and adipocyte hyperplasia/hypertrophy. Obesity inhibits the "browning" of white adipose tissue. Cannabinoid receptor 2 (CB2) agonists reduce food intake and induce anti-obesity effect in mice. A common missense CB2-variant, Q63R, causes CB2 reduced function.
Cannabinoid receptor 2 as anti-obesity target: inflammation, fat storage and browning modulation
PERRONE, MARIA LUCIA;LOCATELLI, FRANCO;
2016-01-01
Abstract
Obesity is associated with a low-grade inflammatory state, and adipocyte hyperplasia/hypertrophy. Obesity inhibits the "browning" of white adipose tissue. Cannabinoid receptor 2 (CB2) agonists reduce food intake and induce anti-obesity effect in mice. A common missense CB2-variant, Q63R, causes CB2 reduced function.File in questo prodotto:
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