Aim. Hybrid repair of aortic arch pathologies consisting in supra-aortic trunks re-routing and arch endograft exclusion, has been shown, in selected patients, to be a feasible and attractive alternative to the conventional open surgery. The aim of this study was to compare the technical and clinical outcomes recorded in the different anatomical settings of endografting for aortic arch disease. Methods. Between January 1999 and October 2008, 292 patients were treated for diseases of thoracic aorta with stent-graft at our Institution; the aortic arch was involved in 106 cases (92 males, mean age 70.6±10.7. Patients were divided into 3 groups according to Ishimaru's classification, zone "0" 22 cases, zone "1" 23 cases, zone "2": 61 cases. Seventy cases were treated with an hybrid approach that consisted in supraortic vessels debranching and successive endovascular exclusion of the aortic arch pathology. Results. Zone "0": proximal neck length after debranching was 43.9±5.6 mm. Initial clinical success 82%: 3 deaths (stroke), 1 type Ia endoleak. At a mean follow-up of 24.7±17 months the midterm clinical success was 86%. Zone "1": proximal neck length: 29±5 mm. Initial clinical success 83%: 0 deaths, 4 type Ia endoleaks. At a mean follow-up of 20.1±16 months the midterm clinical success was 91%. Zone "2": proximal neck length after debranching was 30.4±5.0 mm, clinical success was 90.2%: 1 death, 4 type I endoleaks. At a mean follow-up of 33.4±19.2 months the midterm clinical success was 95.1%: 3 type I endoleak spontaneous resolutions, 1 conversion. Conclusions. Hybrid treatment of aortic arch pathologies is technically feasible with reasonable morbidity and mortality rates at short and midterm follow-up. Total de-branching of the arch for "zone 0" aneurysms allowed to obtain a longer proximal aortic landing zone with lower incidence of endoleak, however a higher risk of cerebrovascular accident was observed. The relatively high incidence of adverse events in "zone 1" could be associated to a shorter proximal neck, therefore this landing zone is reserved for patients unfit for sternotomy.

Midterm results of endovascular treatment of aortic arch

MARONE, ENRICO MARIA;
2010-01-01

Abstract

Aim. Hybrid repair of aortic arch pathologies consisting in supra-aortic trunks re-routing and arch endograft exclusion, has been shown, in selected patients, to be a feasible and attractive alternative to the conventional open surgery. The aim of this study was to compare the technical and clinical outcomes recorded in the different anatomical settings of endografting for aortic arch disease. Methods. Between January 1999 and October 2008, 292 patients were treated for diseases of thoracic aorta with stent-graft at our Institution; the aortic arch was involved in 106 cases (92 males, mean age 70.6±10.7. Patients were divided into 3 groups according to Ishimaru's classification, zone "0" 22 cases, zone "1" 23 cases, zone "2": 61 cases. Seventy cases were treated with an hybrid approach that consisted in supraortic vessels debranching and successive endovascular exclusion of the aortic arch pathology. Results. Zone "0": proximal neck length after debranching was 43.9±5.6 mm. Initial clinical success 82%: 3 deaths (stroke), 1 type Ia endoleak. At a mean follow-up of 24.7±17 months the midterm clinical success was 86%. Zone "1": proximal neck length: 29±5 mm. Initial clinical success 83%: 0 deaths, 4 type Ia endoleaks. At a mean follow-up of 20.1±16 months the midterm clinical success was 91%. Zone "2": proximal neck length after debranching was 30.4±5.0 mm, clinical success was 90.2%: 1 death, 4 type I endoleaks. At a mean follow-up of 33.4±19.2 months the midterm clinical success was 95.1%: 3 type I endoleak spontaneous resolutions, 1 conversion. Conclusions. Hybrid treatment of aortic arch pathologies is technically feasible with reasonable morbidity and mortality rates at short and midterm follow-up. Total de-branching of the arch for "zone 0" aneurysms allowed to obtain a longer proximal aortic landing zone with lower incidence of endoleak, however a higher risk of cerebrovascular accident was observed. The relatively high incidence of adverse events in "zone 1" could be associated to a shorter proximal neck, therefore this landing zone is reserved for patients unfit for sternotomy.
2010
Medical Research, Diagnosis & Treatment contains studies of existing and developing diagnostic and therapeutic techniques, as well as specific classes of clinical intervention. Resources in this category emphasize the difference between normal and disease states, with the ultimate goal of more effective diagnosis and intervention. Specific areas of interest include pathology and histochemical analysis of tissue, clinical chemistry and biochemical analysis of medical samples, diagnostic imaging, radiology and radiation, surgical research, anesthesiology and anesthesia, transplantation, artificial tissues, and medical implants. Resources focused on the disease, diagnosis, and treatment of specific organs or physiological systems are excluded and are covered in the Medical Research: Organs & Systems category.
Inglese
Nazionale
17
3
177
187
11
Aneurysms; Aorta, thoracic; Aortic arch syndromes
https://www.scopus.com/inward/record.uri?eid=2-s2.0-78649336413&partnerID=40&md5=8c0a289aa5009baa8bc5094045d177db
6
info:eu-repo/semantics/article
262
Bertoglio, L.; Civilini, E.; Marone, ENRICO MARIA; Tshomba, Y.; Melissano, G.; Chiesa, R.
1 Contributo su Rivista::1.1 Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/1153522
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