Bacteriology has embraced the next-generation sequencing revolution, swiftly moving from the time of single genome sequencing to the age of genomic epidemiology. Hundreds and now even thousands of genomes are being sequenced for single bacterial species, allowing unprecedented levels of resolution and insight in the evolution and epidemic diffusion of the main bacterial pathogens. Here, we present a review of some of the most recent and groundbreaking studies in this field.

Bacterial genomic epidemiology, from local outbreak characterization to species-history reconstruction

GAIARSA, STEFANO;DE MARCO, LEONE;COMANDATORE, FRANCESCO;SASSERA, DAVIDE
2015-01-01

Abstract

Bacteriology has embraced the next-generation sequencing revolution, swiftly moving from the time of single genome sequencing to the age of genomic epidemiology. Hundreds and now even thousands of genomes are being sequenced for single bacterial species, allowing unprecedented levels of resolution and insight in the evolution and epidemic diffusion of the main bacterial pathogens. Here, we present a review of some of the most recent and groundbreaking studies in this field.
2015
Microbiology covers the biology and biochemistry of microorganisms, bacterial, viral, and parasitic, as well as the medical implications and treatments of the subset of these organisms known to cause disease in humans and/or animals. Biotechnology applications of microorganisms for basic science or clinical use are also covered. Resources that emphasize immune response to pathogens and its modulation by clinical intervention are excluded and are covered in the Immunology category.
Esperti anonimi
Inglese
Internazionale
STAMPA
109
7
319
327
9
Bacteria; Carbapenem-resistant Enterobacteriaceae; Genomic epidemiology; Mycobacterium tuberculosis; Next-generation sequencing; Salmonella Typhi; Staphylococcus aureus; Streptococcus pneumoniae
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768628/
no
6
info:eu-repo/semantics/article
262
Gaiarsa, Stefano; DE MARCO, Leone; Comandatore, Francesco; Marone, P; Bandi, C; Sassera, Davide
1 Contributo su Rivista::1.1 Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/1179163
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