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Accompanied by other rare compounds, a new iridoid dimer, named kurdnestorianoside (1), showing an unprecedented secologanol con␣guration, has been isolated for the ␣rst time from the Kurdish medicinal plant Pterocephalus nestorianus, which is used in Kurdistan for treating oral diseases and in␣ammation. The structure of 1 was established from 1D- and 2D-NMR spectroscopic data. Kaempferol 3-O-[3,6-di-O-(E)-p-coumaroyl]-b-D- glucopyranoside (7) showed a remarkable antiproliferative activity against several human tumor cell lines.

A New Iridoid Dimer and Other Constituents from the Traditional Kurdish Plant Pterocephalus nestorianus Nábělek

ABDULLAH, FUAD OTHMAN ABDULLAH
;Clericuzio, Marco;Porta, Alessio;Vidari, Giovanni
2017-01-01

Abstract

Accompanied by other rare compounds, a new iridoid dimer, named kurdnestorianoside (1), showing an unprecedented secologanol con␣guration, has been isolated for the ␣rst time from the Kurdish medicinal plant Pterocephalus nestorianus, which is used in Kurdistan for treating oral diseases and in␣ammation. The structure of 1 was established from 1D- and 2D-NMR spectroscopic data. Kaempferol 3-O-[3,6-di-O-(E)-p-coumaroyl]-b-D- glucopyranoside (7) showed a remarkable antiproliferative activity against several human tumor cell lines.
2017
The Organic Chemistry/Polymer Science category includes resources concerned with the related fields of organic chemistry and polymer science. The organic chemistry resources deal with compounds of carbon with the exception of certain simple ones, such as the carbon oxides, carbonates, cyanides and cyanates (see Inorganic & Nuclear Chemistry). This category includes research on synthetic and natural organic compounds that may include other elements, such as hydrogen and oxygen, but also nitrogen, halogens, sulphur and phosphorous. Resources concerned with hydrocarbons, organic compounds containing only the elements carbon and hydrogen, are also included in this category. Examples are the alkanes, alkenes, alkynes and aromatics, such as benzene and naphthalene. Polymer science includes all resources dealing with the study, production and technology of polymers, which are compounds composed of very large molecules made up of repeating molecular units (monomers). Polymers may be natural substances, such as polysaccharides or proteins, or synthetic materials, such as nylon or polyethylene.
CHEMISTRY & BIODIVERSITY
sì
WOS:000397537300007
2-s2.0-85014512906
Esperti anonimi
Inglese
Internazionale
STAMPA
14
3
e1600281
8
27982513
Cytotoxic activities; Dipsacaceae; Iridoid dimers; Kurdish medicinal plant; Pterocephalus nestorianus; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Dipsacaceae; Drug Screening Assays, Antitumor; Flowers; Humans; Iridoids; Kaempferols; Magnetic Resonance Spectroscopy; Plants, Medicinal; Bioengineering; Biochemistry; Chemistry (all); Molecular Medicine; Molecular Biology
http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1612-1880
sì
5
info:eu-repo/semantics/article
262
Abdullah, FUAD OTHMAN ABDULLAH; Hussain, Faiq H. S.; Clericuzio, Marco; Porta, Alessio; Vidari, Giovanni
1 Contributo su Rivista::1.1 Articolo in rivista
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1.1 Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/1209714
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