C–H alkylations of purine nucleosides were achieved by means of user-friendly nickel catalysis with ample substrate scope and high levels of chemo, site and regio control, which among others enabled the direct fluorescent labeling of purines in terms of late stage diversification.
Nickel-catalyzed C-H activation of purine bases with alkyl halides
Ghorai, Debasish;Zanoni, GiuseppeConceptualization
;Ackermann, Lutz
Project Administration
2017-01-01
Abstract
C–H alkylations of purine nucleosides were achieved by means of user-friendly nickel catalysis with ample substrate scope and high levels of chemo, site and regio control, which among others enabled the direct fluorescent labeling of purines in terms of late stage diversification.File in questo prodotto:
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Nickel-Catalyzed C‒H Activation of Purine Bases with Alkyl Halides.pdf
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