Graves' disease is the most common cause of hyperthyroidism in iodine-replete areas. Although progress has been made in our understanding of the pathogenesis of the disease, no treatment targeting pathogenic mechanisms of the disease is presently available. Therapies for Graves' hyperthyroidism are largely imperfect because they are bound to either a high rate of relapsing hyperthyroidism (antithyroid drugs) or lifelong hypothyroidism (radioiodine treatment or thyroidectomy). Aim of the present article is to offer a practical guidance to the reader by providing evidence-based answers to frequently asked questions in clinical practice.

Management of hyperthyroidism due to Graves' disease: frequently asked questions and answers (if any).

Chiovato L
Writing – Review & Editing
;
2016-01-01

Abstract

Graves' disease is the most common cause of hyperthyroidism in iodine-replete areas. Although progress has been made in our understanding of the pathogenesis of the disease, no treatment targeting pathogenic mechanisms of the disease is presently available. Therapies for Graves' hyperthyroidism are largely imperfect because they are bound to either a high rate of relapsing hyperthyroidism (antithyroid drugs) or lifelong hypothyroidism (radioiodine treatment or thyroidectomy). Aim of the present article is to offer a practical guidance to the reader by providing evidence-based answers to frequently asked questions in clinical practice.
2016
Endocrinology, Nutrition & Metabolism is a cross-disciplinary category combining molecular, cellular and clinical science studies of the endocrine glands, and the regulation of cell, organ, and system function by the action of secreted hormones. Chemical/biological properties of hormones, and the pathogenesis and treatment of disorders associated with either source or target organs are also covered. Nutrition coverage includes biochemical characteristics of nutrients, physiology of absorption, biological trace elements, clinical nutrition and malnutrition, and the biomedicine of obesity. Specific areas of interest include reproductive endocrinology, pancreatic hormones and diabetes, regulation of bone formation and loss, and control of growth. Resources focusing on neuroendocrinology are excluded and are placed in the Neuroscience & Behavior category.
Esperti anonimi
Inglese
Internazionale
STAMPA
39
10
1105
1114
10
Agranulocytosis, Alemtuzumab, Childhood, Graves’ disease, Graves’ orbitopathy, Hyperthyroidism, Methimazole, Pregnancy, Propylthiouracil, Radioiodine, Thionamides, Thyroidectomy
3
info:eu-repo/semantics/article
262
Bartalena, L; Chiovato, L; Vitti, P
1 Contributo su Rivista::1.1 Articolo in rivista
none
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/1213906
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