In this report we have evaluated the sensitivity and specificity of IHA and ELISA for the detection of anti-amebic antibodies in the serum samples of 147 patients with poor mental and hygienic status hospitalized in mental institutions. Our data have demonstrated a positive agreement between ELISA and IHA on positive sera. The major drawback of IHA is the occurrence of false negative results, 13/82 sera negative in IHA (less than 1/128) are positive in the ELISA. Furthermore, the ELISA is useful for serological diagnosis of amebiasis in the laboratories of low endemic areas.

A comparison of IHA and ELISA tests in the detection of antibodies to entamoeba histolytica

Filice, G;Meroni, V;
1984-01-01

Abstract

In this report we have evaluated the sensitivity and specificity of IHA and ELISA for the detection of anti-amebic antibodies in the serum samples of 147 patients with poor mental and hygienic status hospitalized in mental institutions. Our data have demonstrated a positive agreement between ELISA and IHA on positive sera. The major drawback of IHA is the occurrence of false negative results, 13/82 sera negative in IHA (less than 1/128) are positive in the ELISA. Furthermore, the ELISA is useful for serological diagnosis of amebiasis in the laboratories of low endemic areas.
1984
The Clinical Immunology & Infectious Diseases category covers resources that focus on basic research in clinical and applied allergy, immunology, and infectious disease. Microbiology and virology resources are included in this category as are resources on HIV, AIDS, sexually transmitted diseases (STDs), and hospital infections.
no
Inglese
Locale
STAMPA
63
6
510
512
3
Antibodies; Entamoeba histolytica; Entamoebiasis; False Negative Reactions; Humans; Enzyme-Linked Immunosorbent Assay; Hemagglutination Tests; Immunoenzyme Techniques
5
info:eu-repo/semantics/article
262
Filice, G; Carnevale, G; Meroni, V; Barcella, M; Carosi, G
1 Contributo su Rivista::1.1 Articolo in rivista
none
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/1253826
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