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A new, sensitive and versatile assay for quantitative determination of α-fluoro-β-alanine (AFBA) in human urine by using the reversed-phase ultrahigh performance-tandem mass spectrometry (rp-UHPLC–MS/MS) system

Lonati, Davide;Locatelli, Carlo A.;Pastoris, Ornella;COTTICA, DANILO
2018-01-01
2018
Pharmacology & Toxicology includes all aspects of pharmacology, toxicology, and pharmaceutics. Of particular importance are cellular and molecular pharmacology, drug design and metabolism, mechanisms of drug action, drug delivery, natural products, xenobiotics, and clinical therapeutics. Toxicology coverage considers cellular and molecular effects of harmful substances, environmental toxicology, occupational exposure, and clinical toxicology. Drug bulletins, drug updates, and pharmaceutical newsletters are excluded as are resources on pharmaceutical engineering. Medicinal chemistry, or synthesis and chemical analysis of pharmaceuticals are placed in the Chemistry & Analysis category.
TOXICOLOGY LETTERS
sì
WOS:000454045100226
2-s2.0-85054810924
Esperti anonimi
Inglese
Internazionale
ELETTRONICO
298
164
170
7
30315949
AFBA urinary excretion; Occupational exposure; rp-UHPLC–MS/MS; Validation study; α-Fluoro-β-alanine (AFBA); Antineoplastic Agents; Biotransformation; Calibration; Capecitabine; Fluorouracil; Humans; Occupational Exposure; Occupational Health; Reference Standards; Reproducibility of Results; Risk Assessment; Urinalysis; beta-Alanine; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Health Personnel; Tandem Mass Spectrometry; Toxicology
www.elsevier.com/locate/toxlet
no
10
info:eu-repo/semantics/article
262
Sottani, Cristina; Grignani, Elena; Zarattin, Laura; Santorelli, Donatella; Studioso, Emanuele; Lonati, Davide; Locatelli, Carlo A.; Pastoris, Ornella...espandi
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1.1 Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/1258226
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