Individuals seeking help from prodromal services may have been experiencing attenuated psychotic features and psychosocial impairments for a long period prior to referral. The effect of an extended duration of these untreated 'at risk' symptoms on patients' long-term functional outcome was assessed in a 12-month longitudinal observational study (n=49). A longer duration of untreated 'at risk' symptoms was correlated with a reduced improvement in Global Assessment of Functioning scores after 12 months (β=-0.375, P=0.008). This effect was independent of age and gender and may have implications for the improvement of treatment strategies in pre-psychotic phases.

Duration of untreated prodromal symptoms and 12-month functional outcome of individuals at risk of psychosis

Fusar-Poli P.;
2009-01-01

Abstract

Individuals seeking help from prodromal services may have been experiencing attenuated psychotic features and psychosocial impairments for a long period prior to referral. The effect of an extended duration of these untreated 'at risk' symptoms on patients' long-term functional outcome was assessed in a 12-month longitudinal observational study (n=49). A longer duration of untreated 'at risk' symptoms was correlated with a reduced improvement in Global Assessment of Functioning scores after 12 months (β=-0.375, P=0.008). This effect was independent of age and gender and may have implications for the improvement of treatment strategies in pre-psychotic phases.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/1313596
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