Editorial comment Jiang et al have investigated in vitro the functional characteristics of different point mutations identified in patients with CPVT: their study is not the first of this kind, yet it brings novel insight and provides new arguments that help addressing controversial aspects in the field. In this editorial we will examine the areas of debate in the understanding of CPVT and will discuss the data reported by Jiang et al in the context of the leading speculations that have been elaborated to account for arrhythmogenesis in CPVT.

Intracellular calcium handling dysfunction and arrhythmogenesis: a new challenge for the electrophysiologist

PRIORI, SILVIA GIULIANA;Napolitano Carlo
2005-01-01

Abstract

Editorial comment Jiang et al have investigated in vitro the functional characteristics of different point mutations identified in patients with CPVT: their study is not the first of this kind, yet it brings novel insight and provides new arguments that help addressing controversial aspects in the field. In this editorial we will examine the areas of debate in the understanding of CPVT and will discuss the data reported by Jiang et al in the context of the leading speculations that have been elaborated to account for arrhythmogenesis in CPVT.
2005
Cardiovascular & Hematology Research covers all levels of investigation into the normal and pathogenic functions of the heart, vasculature, and soluble blood components. Cell biology of vascular tissue and formed elements of blood, biochemical regulation of thrombosis, therapeutic strategies for treatment of cardiac and vascular diseases are also considered. Resources on hematologic oncology are excluded and are placed in the Oncogenesis & Cancer Research category.
Sì, ma tipo non specificato
Inglese
Internazionale
STAMPA
97
11
1077
1079
Tematica Ex SIR: Patogenesi molecolare della tachicardia Ventricolare polimorfa catecolaminergica (CPVT) secondaria a mutazioni del gene CASQ2 (Classif. Ex SIR:Articoli su riviste ISI )
Dysfunction; Arrhythmogenesis; Electrophysiologist
http://www.ncbi.nlm.nih.gov/pubmed/16306448
1
info:eu-repo/semantics/article
262
Priori, SILVIA GIULIANA; Napolitano, Carlo
1 Contributo su Rivista::1.1 Articolo in rivista
none
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/132028
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