Camps et al. describe a cell population that blocks fat turnover in the skeletal muscle by single-cell analysis. Furthermore, they show that this population acts through GDF10 secretion and is reduced in dystrophic muscle. This could be an essential turning point in the progressive deterioration of muscular dystrophy patients.

Interstitial Cell Remodeling Promotes Aberrant Adipogenesis in Dystrophic Muscles

Sampaolesi M.
Writing – Review & Editing
2020-01-01

Abstract

Camps et al. describe a cell population that blocks fat turnover in the skeletal muscle by single-cell analysis. Furthermore, they show that this population acts through GDF10 secretion and is reduced in dystrophic muscle. This could be an essential turning point in the progressive deterioration of muscular dystrophy patients.
2020
Esperti anonimi
Inglese
Internazionale
ELETTRONICO
31
5
107597
adipogenesis; GDF10; interstitial stromal cells; muscular dystrophy; single-cell transcriptomics; skeletal muscle
19
info:eu-repo/semantics/article
262
Camps, J.; Breuls, N.; Sifrim, A.; Giarratana, N.; Corvelyn, M.; Danti, L.; Grosemans, H.; Vanuytven, S.; Thiry, I.; Belicchi, M.; Meregalli, M.; Plat...espandi
1 Contributo su Rivista::1.1 Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/1340279
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