Recent studies suggest that liver inflammation in chronic hepatitis C virus (HCV) infection is controlled by several methanisms, including host regulatory immune responess and viral polypeptides interacting with cells involved in innate and adaptive immunity. This article provides an overview about current thinking on host-pathogen symbiotic relationship in HCV infection and its significance with respect to pathogenesis. Special emphasis is given to regulatory T-cell stubsets which have recently received attention and which are thought to plasy a major role in persistent viral infections such as HCV.
Viral and host immune regulatory mechanisms in HCV infection
MONDELLI, MARIO UMBERTO;
2006-01-01
Abstract
Recent studies suggest that liver inflammation in chronic hepatitis C virus (HCV) infection is controlled by several methanisms, including host regulatory immune responess and viral polypeptides interacting with cells involved in innate and adaptive immunity. This article provides an overview about current thinking on host-pathogen symbiotic relationship in HCV infection and its significance with respect to pathogenesis. Special emphasis is given to regulatory T-cell stubsets which have recently received attention and which are thought to plasy a major role in persistent viral infections such as HCV.File in questo prodotto:
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