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The possible neuroprotective effects of classic and new antiepileptic drugs on the electrophysiological changes induced by in vitro ischemia on striatal neurons were investigated. In particular, the aim of the study was to correlate the putative neuroprotective effects with the action of these drugs on fast sodium (Na+) and high-voltage-activated (HVA) calcium (Ca2+) currents.

Multiple mechanisms underlying the neuroprotective effects of antiepileptic drugs against in vitro ischemia

Pisani A;
2006-01-01

Abstract

The possible neuroprotective effects of classic and new antiepileptic drugs on the electrophysiological changes induced by in vitro ischemia on striatal neurons were investigated. In particular, the aim of the study was to correlate the putative neuroprotective effects with the action of these drugs on fast sodium (Na+) and high-voltage-activated (HVA) calcium (Ca2+) currents.
2006
STROKE
no
WOS:000237053900044
2-s2.0-33646701918
Esperti anonimi
Inglese
Internazionale
STAMPA
37
5
1319
1326
8
16574927
Rats; Animals; Carbamazepine; Excitatory Postsynaptic Potentials; Fructose; Potassium; Brain Ischemia; Electrophysiology; Valproic Acid; Calcium Signaling; Anticonvulsants; Ion Transport
https://www.ahajournals.org/doi/10.1161/01.STR.0000217303.22856.38?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub++0pubmed&
no
9
info:eu-repo/semantics/article
262
Costa, C; Martella, G; Picconi, B; Prosperetti, C; Pisani, A; Di Filippo, M; Pisani, F; Bernardi, G; Calabresi, P
1 Contributo su Rivista::1.1 Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/1353577
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