The purpose of the work was to evaluate the effect of different gamma irradiation doses on PEGd,lPLA and PEG-PLGA multiblock copolymers. The behaviour of multiblock copolymers to irradiation was compared to that of PLA and PLGA polymers. The results show that the multiblock copolymers presented higher sensitivity to irradiation treatment with respect to PL, likely do to the presence of PEG in the matrix. The effect of gamma irradiation continues over a much longer period of time after irradiation has been performed.
GAMMA-IRRADIATION OF PEGd,lPLA AND PEG-PLGA MULTIBLOCK COPOLYMERS: I. EFFECT OF IRRADIATION DOSES
DORATI, ROSSELLA;COLONNA, CLAUDIA;SERRA, MASSIMO;GENTA, IDA;MODENA, TIZIANA;PAVANETTO, FRANCA;PERUGINI, PAOLA;CONTI, BICE
2008-01-01
Abstract
The purpose of the work was to evaluate the effect of different gamma irradiation doses on PEGd,lPLA and PEG-PLGA multiblock copolymers. The behaviour of multiblock copolymers to irradiation was compared to that of PLA and PLGA polymers. The results show that the multiblock copolymers presented higher sensitivity to irradiation treatment with respect to PL, likely do to the presence of PEG in the matrix. The effect of gamma irradiation continues over a much longer period of time after irradiation has been performed.File in questo prodotto:
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