The present invention relates to a screening method for the identification of new nitrobenzothiazinone drugs for the treatment of tuberculosis, which are not or are slowly transformed and inactivated by nitroreductase. The use of the nitroreductase NfnB from M. smegmatis in cancer therapy, and in bioremediation are comprised as well.
NITROREDUCTASE NfnB FROM Mycobacterium smegmatis
RICCARDI, GIOVANNA;MANINA, GIULIA;PASCA, MARIA ROSALIA
2008-01-01
Abstract
The present invention relates to a screening method for the identification of new nitrobenzothiazinone drugs for the treatment of tuberculosis, which are not or are slowly transformed and inactivated by nitroreductase. The use of the nitroreductase NfnB from M. smegmatis in cancer therapy, and in bioremediation are comprised as well.File in questo prodotto:
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