In this paper we present FRP (Flow Rate Profiler), an instrument for measuring the blood velocity by means of ultrasound-based techniques. The velocity is directly related to the shear-rate, which is in turn proportional to the shear-stress, a parameter expressing the pressure exerted by the blood on the vessel walls. The knowledge of this value is important in medicine to establish the state of the vessels, directly related to vascular diseases. FRP provides a non-invasive measure of the blood velocity by exploiting the red corpuscles property of diffusing ultrasound waves: in practice blood velocity is determined by a cross-correlation technique, which analyses the time shift between correlated subsequent echo waves, instead of frequency shift characteristic of the Doppler technique. The acquired data are then processed on a Personal Computer by means of mathematical techniques based on the evaluation of the correlation function, giving a reconstructed velocity profile and showing a good adherence with experimental data, since the average error is nearly the 10%. The reconstructed profile is displayed to the operator, who can follow the vessel status in real-time. A few comparisons between the reconstructed and the experimental profiles are also presented, together with a study on a small set of patients suffering from artery hypertension.

Flow Rate Profiler: an instrument to measure blood velocity profiles

LOMBARDI, REMO ANGELO;DANESE, GIOVANNI;LEPORATI, FRANCESCO
2001-01-01

Abstract

In this paper we present FRP (Flow Rate Profiler), an instrument for measuring the blood velocity by means of ultrasound-based techniques. The velocity is directly related to the shear-rate, which is in turn proportional to the shear-stress, a parameter expressing the pressure exerted by the blood on the vessel walls. The knowledge of this value is important in medicine to establish the state of the vessels, directly related to vascular diseases. FRP provides a non-invasive measure of the blood velocity by exploiting the red corpuscles property of diffusing ultrasound waves: in practice blood velocity is determined by a cross-correlation technique, which analyses the time shift between correlated subsequent echo waves, instead of frequency shift characteristic of the Doppler technique. The acquired data are then processed on a Personal Computer by means of mathematical techniques based on the evaluation of the correlation function, giving a reconstructed velocity profile and showing a good adherence with experimental data, since the average error is nearly the 10%. The reconstructed profile is displayed to the operator, who can follow the vessel status in real-time. A few comparisons between the reconstructed and the experimental profiles are also presented, together with a study on a small set of patients suffering from artery hypertension.
2001
Cardiovascular & Hematology Research covers all levels of investigation into the normal and pathogenic functions of the heart, vasculature, and soluble blood components. Cell biology of vascular tissue and formed elements of blood, biochemical regulation of thrombosis, therapeutic strategies for treatment of cardiac and vascular diseases are also considered. Resources on hematologic oncology are excluded and are placed in the Oncogenesis & Cancer Research category.
Sì, ma tipo non specificato
Inglese
Internazionale
STAMPA
39
2
143
150
articolo accettato come eccellente
Instruments and methods; Data acquisition; Ultrasounds
3
info:eu-repo/semantics/article
262
Lombardi, REMO ANGELO; Danese, Giovanni; Leporati, Francesco
1 Contributo su Rivista::1.1 Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/137696
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