Systemic Nickel Allergy Syndrome (SNAS): Taking Stock of Medical Nutrition Therapy SNAS and Nutrition

Nickel is a ubiquitous metal present in different products such as soil, food, and water. Being ubiquitous, it is difficult to avoid contact in everyday life. Moreover, it could be the cause for Nickel allergy, Allergic Contact Dermatitis, and Systemic Nickel Allergy Syndrome. The treatment of patients affected by Systemic Nickel Allergy Syndrome does not yet have a standard protocol. This narrative review proposes an overview of the current knowledge of Systemic Nickel Allergy Syndrome associated with symptomatology, diagnosis, and medical nutrition treatment-related care practices. The authors focus on the studies published in the last ten years with a focus on the Systemic Nickel Allergy Syndrome, its diagnosis, treatment, and the possible solutions. Despite the extensive research in this field, many questions remain regarding the medical treatment of patients with SNAS. Nickel free diets have been highly criticized because of low compliance. At the same time, SNAS remains common and continues to be a health problem in the general population. Clinicians should be aware of the potential chronicity of the disease, resulting in a decreased quality of life and societal and economic impacts. The authors conclude that further and broader studies, more rigorously conducted, are needed to address this issue.