The main scope of this Special issue was to gain understanding on how tissues and organs are arranged into integrative hierarchical levels of complexity, fromthemolecular to themorphological organization. To understand the underlying complexity of the relationships among these levels during morphogenesis or in the adult we must learn how to resolve single-cell spatial relationships in the three-dimensional (3D) organization of tissues, organs, and even of the whole organisms. Each paper in this “Frontiers” special issue contributes to deepen our understanding on the dynamics and mechanisms of development and differentiation in the complexity of the 3D architecture of embryos, intact organs, or organoids.
Editorial: 3D Modeling of Mammalian Embryos and Organs
Garagna S
;Zuccotti M
2021-01-01
Abstract
The main scope of this Special issue was to gain understanding on how tissues and organs are arranged into integrative hierarchical levels of complexity, fromthemolecular to themorphological organization. To understand the underlying complexity of the relationships among these levels during morphogenesis or in the adult we must learn how to resolve single-cell spatial relationships in the three-dimensional (3D) organization of tissues, organs, and even of the whole organisms. Each paper in this “Frontiers” special issue contributes to deepen our understanding on the dynamics and mechanisms of development and differentiation in the complexity of the 3D architecture of embryos, intact organs, or organoids.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
