Immunotherapy may represent an available method in addition to the traditional therapeutic approaches. Starting from 1991, we set up a cellular model of lymphocytes obtained from peripheral blood of healthy patients treated with interleukin-2 (IL-2) in order to study the role of IL-2 in regulating lymphocytes activation. The lymphocytes responding to IL-2 treatment, named lymphokineactivated killer (LAK) cells, have a killer non MHC restricted activity, and are able to kill autologous and allogenic glioma cells.

Immunobiological and experimental aspects of malignant astrocytoma: a review.

NANO, ROSANNA;CAPELLI, ENRICA;FACOETTI, ANGELICA;
2009-01-01

Abstract

Immunotherapy may represent an available method in addition to the traditional therapeutic approaches. Starting from 1991, we set up a cellular model of lymphocytes obtained from peripheral blood of healthy patients treated with interleukin-2 (IL-2) in order to study the role of IL-2 in regulating lymphocytes activation. The lymphocytes responding to IL-2 treatment, named lymphokineactivated killer (LAK) cells, have a killer non MHC restricted activity, and are able to kill autologous and allogenic glioma cells.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11571/146710
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