In November 2021, a 65-year-old man was admitted to our hospital with acute pulmonary oedema. He had a two-year history of erosive rheumatoid arthritis (RA), positive for both rheumatoid factor and anti-citrullinated protein antibodies, and without any sign of extra-articular involvement, including cutaneous vasculitis or subcutaneous nodules. His clinical history was negative apart from well-controlled hypertension. The patient, who was initially refractory to methotrexate, was started on an anti-tumour necrosis factor-α (anti-TNF-α) monoclonal antibody (golimumab) in November 2018, reaching sustained remission with no side effects. The patient presented with orthopnoea, cyanosis, and diaphoresis.
A case of a rheumatoid nodule on the aortic valve in a patient with rheumatoid arthritis in sustained remission with anti-TNFα
De Stefano, L
;Pelizza, J;Ferracane, G;Piccin, V;Montecucco, C;Bugatti, S
2023-01-01
Abstract
In November 2021, a 65-year-old man was admitted to our hospital with acute pulmonary oedema. He had a two-year history of erosive rheumatoid arthritis (RA), positive for both rheumatoid factor and anti-citrullinated protein antibodies, and without any sign of extra-articular involvement, including cutaneous vasculitis or subcutaneous nodules. His clinical history was negative apart from well-controlled hypertension. The patient, who was initially refractory to methotrexate, was started on an anti-tumour necrosis factor-α (anti-TNF-α) monoclonal antibody (golimumab) in November 2018, reaching sustained remission with no side effects. The patient presented with orthopnoea, cyanosis, and diaphoresis.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
